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Metabolic gene expression changes in astrocytes in Multiple Sclerosis cerebral cortex are indicative of immune-mediated signaling

Autor: Pierre J. Magistretti, Igor Allaman, Nicole Schaeren-Wiemers, Melanie Gentner, J. Tschopp, Thomas Zeis, Kate Schroder

Publikováno v: Brain Behavior and Immunity
Brain behavior and immunity
Brain, Behavior, and Immunity, vol. 48, pp. 313-325

Emerging as an important correlate of neurological dysfunction in Multiple Sclerosis (MS), extended focal and diffuse gray matter abnormalities have been found and linked to clinical manifestations such as seizures, fatigue and cognitive dysfunction.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4564e8745efac7fd001abb08a1b033ae

[Loco-regional complications of pharyngitis: the example of Lemierre's syndrome]

Autor: J, Tschopp, C, Chuard

Publikováno v: Revue medicale suisse. 11(489)

Pharyngitis is a common cause of consultation in ambulatory medicine. Although it is benign in most cases, serious complications may happen and must be recognized quickly. Lemierre's syndrome is one of them. It consists in the association of thrombos

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5544e88b1a8a1ceb40fff8c88477b8b5
https://pubmed.ncbi.nlm.nih.gov/26638515

Th17 (PP-014)

Autor: A. E. Hauser, H. Wu, E. Esplugues, M. Tsuruoka, W. Niedbala, J. Elia, S. Tsuyoshi, B. Cai, V. Flamand, S. Iwamoto, M. Hirashima, S. Tanaka, H. L. Qian, H. Kai, C. Yu, A. Yoshimura, A. Yamauchi, J. Masuyama, Y. Kang, J. M. Wilson, J. Rohrer, T. Tanaka, M. Weinstein, F. Tsuji, D. Chuang, Y. Xiao, S. Yamada, E. A. M. Veraar, S. Wu, Yoh-ichi Tagawa, T. Kamiyama, S. M. Vieira, M. Tajima, S. Huber, J. C. Alves-Filho, F. Suzuki, J. Rabenstein, M. Kadowaki, K. Masuko, C. Liu, I. Debock, S. Oomizu, A. Chu, H. Aono, J. Kang, J. Lastovicka, K. Ishihara, A. Sediva, T. Arikawa, N. Malhotra, S. Miuznoe, B. Oh, X. Wang, F. Zhu, H. Yasuhara, J. M. Coquet, S. Lee, I. Matumoto, D. Wakita, T. Koga, Katsuko Sudo, K. Matsushima, S. Saijo, F. Q. Cunha, U. A. K. Betz, A. Ikejiri, H. Park, S. Y. Fukada, J. Yoon, H. Uga, O. Beretta, D. Noguchi, C. Chu, M. Roecken, H. Sepulveda, B. A. Wu-Hsieh, T. Matsuda, T. Okazawa, S. Kim, H. Hirota, H. Kitamura, Y. Liu, D. N. Herndon, T. Town, F. Liu, A. Yazdi, T. Niki, H. Lee, C. Deng, M. Kono, S. Feske, N. Ueda, R. Horvath, T. Sumida, G. Licandro, T. Nishimura, M. Harada, S. Koyasu, P. B. Ernst, M. Murakami, T. Sato, M. Suico, S. Black, M. Kanayama, Kazuo Sugane, C. Kitabayashi, K. Ghoreschi, C. Matsumoto, R. A. Flavell, T. Atsumi, M. G. Jeschke, E. A. O'Donnell, M. Nishihara, J. Borst, M. Kobayashi, Z. Lining, R. Spreafico, J. Morimoto, H. Ogura, A. Haberman, T. Kaisho, M. Pétein, N. Gagliani, T. Fukada, A. Miyazaki, J. Tschopp, G. van der Horst, J. Soh, S. Park, Yoichiroh Iwakura, T. Hu, S. Delbauve, Q. Wang, J. Ma, D. C. Gruenert, A. Mitani, Y. Miyamoto, S. Ikeda, P. Ricciardi-Castagnoli, S. Iwai, H. Watanabe, E. Huseby, T. Uede, S. Suzuki, C. McCarl, S. Hida, K. Ichiyama, I. Glocova, I. Azuma, S. Hojyo, K. Oguchi, F. Y. Liew, A. Mortellaro, J. Yu, M. Goldman, S. Nakae, A. Polouckova, J. Brueck, W. Ohashi, R. Spisek, M. Ikeda, T. Hirano, A. Inatsu, O. Kim, C. Conforti-Andreoni, M. Yanagida, S. Khalil, Masaya Takamoto, M. Festing, M. Mamura, S. Miaw, H. Kurata, M. Kanamoto, S. Nagai, U. Ikeda

Publikováno v: International Immunology. 22:i96-i101

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::88215d3af015208cab10445f1625ca06
https://doi.org/10.1093/intimm/dxq101

Activation of the NALP3 inflammasome is triggered by low intracellular potassium concentration

Autor: J. Tschopp, Fabio Martinon, Virginie Pétrilli, Annick Mayor, Papin S, Catherine Dostert

Publikováno v: Cell Death & Differentiation. 14:1583-1589

Inflammasomes are Nod-like receptor(NLR)- and caspase-1-containing cytoplasmic multiprotein complexes, which upon their assembly, process and activate the proinflammatory cytokines interleukin (IL)-1beta and IL-18. The inflammasomes harboring the NLR

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9620478eaa16270aae61799fc36d441d
https://doi.org/10.1038/sj.cdd.4402195