Zobrazeno 1 - 10
of 2 452
pro vyhledávání: '"J, Tremblay"'
Publikováno v:
Quality Advancement in Nursing Education, Vol 10, Iss 2 (2024)
Externí odkaz:
https://doaj.org/article/76d545cdeb074ad2897e4b7c163aa765
Publikováno v:
Endocrines, Vol 4, Iss 3, Pp 573-594 (2023)
Leydig cells, located in the testis interstitial space, are the primary source of testosterone in males. Testosterone plays critical roles in both reproductive and metabolic functions and therefore is essential for male health. Steroidogenesis must b
Externí odkaz:
https://doaj.org/article/1c4d34b603294e1d8a5d8c3fe8eee1cb
Publikováno v:
Current Research in Toxicology, Vol 6, Iss , Pp 100147- (2024)
Ethylene dimethanesulfonate (EDS) is a molecule with known selective cytotoxicity on adult Leydig cells. A single intraperitoneal injection in rats but not mice, leads to male androgen deprivation and infertility. In vitro studies using rat and mouse
Externí odkaz:
https://doaj.org/article/e849b22db65d43169701bcac2fb3aa23
Autor:
Robert Lodge, Zaikun Xu, Mckenna Eklund, Christina Stürzel, Frank Kirchhoff, Michel J. Tremblay, Tom C. Hobman, Éric A. Cohen
Publikováno v:
mBio, Vol 14, Iss 5 (2023)
ABSTRACT The type 1 interferon-regulated E3 ubiquitin ligase MARCH1 reduces surface expression of HIV-1 envelope glycoproteins (Env) and their packaging into nascent virions, a condition that restricts viral infectivity. However, how HIV-1 counters t
Externí odkaz:
https://doaj.org/article/d691c612579c4ccfb0b25dd7e74b1bb7
Publikováno v:
Journal of Applied Economics, Vol 25, Iss 1, Pp 731-740 (2022)
An owner of a firm may choose to hire an unbiased CEO or one with confidence bias. We develop a model that demonstrates that the owner’s optimal choice depends on whether the firm and rival choice variables are strategic substitutes or strategic co
Externí odkaz:
https://doaj.org/article/423c46745eae4ccabceecfeaf74962d3
Publikováno v:
Endocrines, Vol 3, Iss 3, Pp 460-475 (2022)
Leydig cells produce androgens which are essential for male sex differentiation and reproductive functions. Steroidogenesis, as well as expression of several genes in Leydig cells, are stimulated by LH/cAMP and repressed by AMP/AMPK. One of those gen
Externí odkaz:
https://doaj.org/article/13056404c4264497be7c3f065dce90a5
Autor:
Lipsitz, Michael, J. Tremblay, Mark
Publikováno v:
American Economic Journal: Microeconomics; Nov2024, Vol. 16 Issue 4, p112-153, 42p
Publikováno v:
Endocrines, Vol 3, Iss 1, Pp 16-28 (2022)
Members of the pre-B-cell leukemia transcription factor (PBX) family of homeoproteins are mainly known for their involvement in hematopoietic cell differentiation and in the development of leukemia. The four PBX proteins, PBX1, PBX2, PBX3 and PBX4, b
Externí odkaz:
https://doaj.org/article/e0588305bfdc45a790e4ae584edf81f0
Publikováno v:
Immunity, Inflammation and Disease, Vol 11, Iss 1, Pp n/a-n/a (2023)
Abstract Introduction HIV‐1 eradication is hindered by the presence of inducible long‐lived reservoirs of latently infected cells which rapidly disseminate viral particles upon treatment interruption. Eliminating these reservoirs by the so‐call
Externí odkaz:
https://doaj.org/article/7611f6b427ec4069ab54a28524e678bf
Autor:
Ramon Edwin Caballero, Simon Xin Min Dong, Niranjala Gajanayaka, Hamza Ali, Edana Cassol, William D. Cameron, Robert Korneluk, Michel J. Tremblay, Jonathan Angel, Ashok Kumar
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-18 (2021)
Abstract Macrophages serve as viral reservoirs due to their resistance to apoptosis and HIV-cytopathic effects. We have previously shown that inhibitor of apoptosis proteins (IAPs) confer resistance to HIV-Vpr-induced apoptosis in normal macrophages.
Externí odkaz:
https://doaj.org/article/e042e27adcd1469d86cdf4e6c7ba50c4