Zobrazeno 1 - 10
of 1 072
pro vyhledávání: '"J, Toledo"'
Autor:
Milene M. Hornink, Monica F. Z. J. Toledo, Daniel C. Pimenta, Caio Paschoalin, Pamela M. Silva, Giuseppe E. Figlino, Eurípedes Aguiar, Gustavo Cervi, Francisco W. M. Ribeiro, Thiago Carita Correra, Angélique Ferry, Hélio A. Stefani
Publikováno v:
ACS Omega, Vol 9, Iss 29, Pp 31732-31744 (2024)
Externí odkaz:
https://doaj.org/article/2d3f0acf71ff481e80a49b050f81666f
Autor:
Maurício T. Tavares, Arne Krüger, Sun L. Rei Yan, Karoline B. Waitman, Vinícius M. Gomes, Daffiny Sumam de Oliveira, Franciarli Paz, Sebastian Hilscher, Mike Schutkowski, Wolfgang Sippl, Claudia Ruiz, Mônica F. Z. J. Toledo, Neuza M. A. Hassimotto, João A. Machado-Neto, Antti Poso, Michael D. Cameron, Thomas D. Bannister, Giuseppe Palmisano, Carsten Wrenger, Thales Kronenberger, Roberto Parise-Filho
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-20 (2023)
Abstract We report a series of 1,3-diphenylureido hydroxamate HDAC inhibitors evaluated against sensitive and drug-resistant P. falciparum strains. Compounds 8a–d show potent antiplasmodial activity, indicating that a phenyl spacer allows improved
Externí odkaz:
https://doaj.org/article/661e63afc62b4a918f5086fa3323ea43
Autor:
G. Carola, D. Malagarriga, C. Calatayud, M. Pons-Espinal, L. Blasco-Agell, Y. Richaud-Patin, I. Fernandez-Carasa, V. Baruffi, S. Beltramone, E. Molina, P. Dell’Era, J. J. Toledo-Aral, E. Tolosa, A. R. Muotri, J. Garcia Ojalvo, J. Soriano, A. Raya, A. Consiglio
Publikováno v:
npj Parkinson's Disease, Vol 7, Iss 1, Pp 1-14 (2021)
Abstract A deeper understanding of early disease mechanisms occurring in Parkinson’s disease (PD) is needed to reveal restorative targets. Here we report that human induced pluripotent stem cell (iPSC)-derived dopaminergic neurons (DAn) obtained fr
Externí odkaz:
https://doaj.org/article/7c8c8c544c2b4347a40c5da25a5f23b4
Autor:
Adriano Quaresma, Charles E. Zartman, Maria T. F. Piedade, Florian Wittmann, Mario A. G. Jardim, Mariana V. Irume, Ana M. Benavides, Leandro Freitas, José J. Toledo, Carlos R. Boelter, Flávio Obermüller, Alvaro J. Duque, Viviane P. Klein, Maikel L. G. Mari, Jochen Schöngart, Edith Arenas, Edwin T. Pos, Alejandra Vasco, Renske Ek, Faline D. M. Plantenga, Joost F. Duivenvoorden, Koos Biesmeijer, Irene M. A. Bender, Hans ter Steege
Publikováno v:
Frontiers in Forests and Global Change, Vol 5 (2022)
Epiphytes are still an understudied plant group in Amazonia. The aim of this study was to identify distributional patterns and conservation priorities for vascular epiphyte assemblages (VEA) across Amazonia. We compiled the largest Amazonian epiphyte
Externí odkaz:
https://doaj.org/article/3e09919cc15e44b6814b20498f4e16af
Autor:
J. Caetano, J. Toledo
Publikováno v:
Journal of High Energy Physics, Vol 2019, Iss 1, Pp 1-64 (2019)
Abstract We consider the strong coupling limit of 4-point functions of heavy operators in N $$ \mathcal{N} $$ = 4 SYM dual to strings with no spin in AdS. We restrict our discussion for operators inserted on a line. The string computation factorizes
Externí odkaz:
https://doaj.org/article/2ef1fd4950a84a069d6aecc80e62bb48
Autor:
Joel J. Toledo Mauriño, Gabriela Fonseca-Camarillo, Janette Furuzawa-Carballeda, Rafael Barreto-Zuñiga, Braulio Martínez Benítez, Julio Granados, Jesus K. Yamamoto-Furusho
Publikováno v:
Journal of Immunology Research, Vol 2020 (2020)
Introduction. TRPVs are a group of receptors with a channel activity predominantly permeable to Ca2+. This subfamily is involved in the development of gastrointestinal diseases such as ulcerative colitis (UC). The aim of the study was to characterize
Externí odkaz:
https://doaj.org/article/6d027295729d4d6ab5da162bb51e329f
Autor:
Leandro Cortes-Ávila, José J. Toledo
Publikováno v:
Actualidades Biológicas, Vol 35, Iss 99, Pp 185-197 (2017)
Los bosques del municipio de San Vicente del Caguán (Caquetá), Colombia, han sido rápidamente degradados y convertidos en áreas de pastizal en las últimas décadas, causando la pérdida de biodiversidad, aislamiento de poblaciones y en el peor d
Externí odkaz:
https://doaj.org/article/9d97735bf6504ca094c1a869ff00de7d
Publikováno v:
Cognitive Neurodynamics. 17:385-398
People with impaired motor function could be helped by an effective brain–computer interface (BCI) based on a real-time electroencephalogram (EEG) and artificial intelligence algorithms. However, current methodologies for interpreting patient instr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7d328fc2b000b33ec06094b1521adfe0
https://doi.org/10.1007/s11571-022-09832-z
https://doi.org/10.1007/s11571-022-09832-z
Akademický článek
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Autor:
Jannette Rodriguez-Pallares, Ana I. Rodriguez-Perez, Ana Muñoz, Juan A. Parga, Juan J. Toledo-Aral, Jose L. Labandeira-Garcia
Publikováno v:
Stem Cells Translational Medicine, Vol 5, Iss 6, Pp 804-815 (2016)
In models of Parkinson's disease (PD), Rho kinase (ROCK) inhibitors have antiapoptotic and axon‐stabilizing effects on damaged neurons, decrease the neuroinflammatory response, and protect against dopaminergic neuron death and axonal retraction. RO
Externí odkaz:
https://doaj.org/article/21085baf5c92473caf51b01bad505ff9