Zobrazeno 1 - 10
of 200
pro vyhledávání: '"J, Thody"'
Autor:
K Gledhill, Mojgan Masoodi, Lesley E. Rhodes, Anthony J. Thody, Desmond J. Tobin, Anna Nicolaou, M Brownrigg, Ann K. Haylett
Publikováno v:
Pigment Cell & Melanoma Research. 23:394-403
Excessive ultraviolet radiation (UVR) exposure induces erythema, mediated in part by prostaglandin-E(2) (PGE(2)). While keratinocytes are a major PGE(2) source, epidermal melanocytes (EM) also express PGE(2)-production machinery. It is unclear whethe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::89369250c9f9669a5b2d6ce9530835a6
https://doi.org/10.1111/j.1755-148x.2010.00696.x
https://doi.org/10.1111/j.1755-148x.2010.00696.x
Autor:
Anna Nicolaou, Anthony J. Thody, Desmond J. Tobin, Ann K. Haylett, Mojgan Masoodi, Lesley E. Rhodes, M Brownrigg, K Gledhill
Publikováno v:
The FASEB Journal
Sunburn is a commonly occurring acute inflammatory process, with dermal vasodilatation and leukocyte infiltration as central features. Ultraviolet (UV) B-induced hydrolysis of membrane phospholipids releases polyunsaturated fatty acids, and their sub
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a3b607e4de0dd5b3336bc8322529d54
https://doi.org/10.1096/fj.09-136077
https://doi.org/10.1096/fj.09-136077
Autor:
Anthony J. Thody, Söbia Kauser, Karine Rousseau, Robert L. Oliver, Edward T. Wei, A Warhurst, Desmond J. Tobin, Andrzej Slominski, L E Pritchard, Anne White
Publikováno v:
The FASEB Journal. 21:1844-1856
Proopiomelanocortin (POMC) can be processed to ACTH and melanocortin peptides. However, processing is incomplete in some tissues, leading to POMC precursor release from cells. This study examined POMC processing in human skin and the effect of POMC o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ddb021d1235b146ddca4a7aaa22dcfe
https://doi.org/10.1096/fj.06-7398com
https://doi.org/10.1096/fj.06-7398com
Publikováno v:
British Journal of Dermatology. 92:43-47
SUMMARY Plasma β-MSH levels and sebum excretion rates (SER) were measured in thirty male and twelve female patients with acne vulgaris. The mean SER in both male and female patients was significantly increased as compared to normal control levels. P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a1fb11c672804b2e52a18ff090e4415d
https://doi.org/10.1111/j.1365-2133.1975.tb03031.x
https://doi.org/10.1111/j.1365-2133.1975.tb03031.x
Publikováno v:
Europe PubMed Central
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11f95fe3476782da0c1656be39f6abf7
https://doi.org/10.1111/j.1749-6632.1999.tb08714.x
https://doi.org/10.1111/j.1749-6632.1999.tb08714.x
Autor:
Anthony J. Thody
Publikováno v:
Annals of the New York Academy of Sciences. 885:217-229
alpha-MSH, has numerous actions in the skin and by activating the MC1 receptor (MC1-R) on melanocytes it stimulates melanogenesis. Rather than producing large increase in melanin production alpha-MSH acts specifically to stimulate eumelanin synthesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f84476beadbf733ac6bb82a779352b0d
https://doi.org/10.1111/j.1749-6632.1999.tb08679.x
https://doi.org/10.1111/j.1749-6632.1999.tb08679.x
Autor:
Söbia Kauser, Desmond J. Tobin, Karin U. Schallreuter, Christopher Lawrence Gummer, Anthony J. Thody
Publikováno v:
Endocrinology. 146:532-543
The proopiomelanocortin (POMC)-derived peptides, ACTH and alpha-MSH, are the principal mediators of human skin pigmentation via their action at the melanocortin-1 receptor (MC-1R). Recent data have demonstrated the existence of a functionally active
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16dc4581848dfc504b03859490d3ceba
https://doi.org/10.1210/en.2004-1145
https://doi.org/10.1210/en.2004-1145
Publikováno v:
FEBS Letters. 570:223-226
Prostaglandins are potent mediators of the inflammatory response and are also involved in cancer development. In this study, we show that human melanocytes and FM55 melanoma cells express cyclooxygenase-1 and -2 (COX-1 and -2) and thus have the capab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b18a0b60c6c50a8e3fce58d33a980560
https://doi.org/10.1016/j.febslet.2004.06.041
https://doi.org/10.1016/j.febslet.2004.06.041
Autor:
Desmond J. Tobin, Söbia Kauser, Christopher Lawrence Gummer, Anthony J. Thody, Karin U. Schallreuter
Publikováno v:
Journal of Investigative Dermatology. 123(1):184-195
The pro-opiomelanocortin (POMC)-derived peptides, alpha-melanocyte-stimulating hormone, and adrenocorticotropic hormone, are important mediators of human skin pigmentation via action at the melanocortin-1 receptor. Recent data suggests that such a re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19de9a1d54714af4fea7ec4cabb75ccd