Zobrazeno 1 - 10
of 77
pro vyhledávání: '"J, Swaine"'
Autor:
Chee Onn Leong, Marie Suggitt, David J. Swaine, Michael C. Bibby, Malcolm F.G. Stevens, Tracey D. Bradshaw
Publikováno v:
Molecular Cancer Therapeutics. 3:1565-1575
Phortress is a novel, potent, and selective experimental antitumor agent. Its mechanism of action involves induction of CYP1A1-catalyzed biotransformation of 2-(4-amino-3-methylphenyl)-5-fluorobenzothiazole (5F 203) to generate electrophilic species,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d26f2552d0067d5fa8f07216294c5354
https://doi.org/10.1158/1535-7163.1565.3.12
https://doi.org/10.1158/1535-7163.1565.3.12
Publikováno v:
Clinical Cancer Research. 10:6677-6685
Purpose: The hollow fiber assay is used successfully as a routine in vivo screening model to quantitatively define anticancer activity by the National Cancer Institute. This study investigates whether the hollow fiber assay can be used as a short-ter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c422d57c29b3a93135e99609b4d3da0
https://doi.org/10.1158/1078-0432.ccr-04-0855
https://doi.org/10.1158/1078-0432.ccr-04-0855
Autor:
Gerald Blunden, Peter A. Linley, Colin W. Wright, Nagwa Shoeib, Michael C. Bibby, Richard T. Wheelhouse, David J. Swaine
Publikováno v:
Journal of Natural Products. 67:1445-1449
Bioassay-guided fractionation was applied to the cytotoxic chloroform fraction of the red alga Polysiphonia lanosa. The major compounds of the most active fraction were identified using GLC-MS analysis as lanosol (1), methyl, ethyl, and n-propyl ethe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84887b5336b044d9696c0143fc9bdc0a
https://doi.org/10.1021/np0305268
https://doi.org/10.1021/np0305268
Autor:
Roger M. Phillips, John A. Double, Valérie Pavillard, Anna Nicolaou, Abedalnaser A.A. Drbal, David J. Swaine
Publikováno v:
Biochemical Pharmacology. 67:1587-1599
Methionine dependence is a feature unique to cancer cells, exhibited as inability to grow in a methionine-depleted environment supplemented with homocysteine, the immediate metabolic precursor of methionine. This study explores the effect of methioni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1081c444e6be4cb7a0bf6968a4544ea
https://doi.org/10.1016/j.bcp.2004.01.006
https://doi.org/10.1016/j.bcp.2004.01.006
Autor:
Mike C. Bibby, Steve D. Shnyder, David J. Swaine, George R. Pettit, Ian G. Kirwan, Patricia A. Cooper, Paul M. Loadman, D. Alan Anthoney, John W. Lippert
Publikováno v:
Clinical Cancer Research. 10:1446-1453
Purpose: Combretastatin A4 phosphate (CA4P) and its structural analog, combretastatin A1 phosphate (CA1P), are soluble prodrugs capable of interacting with tubulin and causing rapid vascular shutdown within tumors. CA4P has completed Phase I clinical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::130a3a301a376e9bd5a3d53f8dacb56c
https://doi.org/10.1158/1078-0432.ccr-0518-03
https://doi.org/10.1158/1078-0432.ccr-0518-03
Autor:
Dalway J. Swaine
Publikováno v:
Fuel Processing Technology. :21-33
The widespread presence of trace elements is shown by reviewing their roles during the mining, beneficiation and combustion of coal and during metal mining and treatments. Special attention is given to Hg, to the environmentally important mineral, py
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::71720db2b63051ef773540f3d02de044
https://doi.org/10.1016/s0378-3820(99)00073-9
https://doi.org/10.1016/s0378-3820(99)00073-9
Autor:
Dalway J. Swaine
Publikováno v:
Coal Preparation. 19:177-193
Relevant published information is reviewed and assessed for the effects of mining and beneficiation on trace elements in coal. In general, the concentrations of those elements associated with mineral matter are decreased to varying degrees depending
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8dd0ce91f47b3158e23fbded5d1f2bd9
https://doi.org/10.1080/07349349808945580
https://doi.org/10.1080/07349349808945580
Autor:
Dalway J. Swaine
Publikováno v:
Environmental geochemistry and health. 14(1)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7d51c25b644e9767d173658e0ac9291
https://pubmed.ncbi.nlm.nih.gov/24197894
https://pubmed.ncbi.nlm.nih.gov/24197894
Autor:
Fariborz Goodarzi, Dalway J. Swaine
Publikováno v:
Chemical Geology. 118:301-318
The concentration of boron in Australian and Canadian coals determined using atomic emission spectrometry (AES), inductively coupled plasma spectrometry (ICP-AES) and prompt gamma-ray spectrometry is summarized in order to assess the variation of B c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a7998e3cd0256245a5729c83edbfcd0
https://doi.org/10.1016/0009-2541(94)90183-x
https://doi.org/10.1016/0009-2541(94)90183-x
Autor:
Dalway J. Swaine
Publikováno v:
Fuel Processing Technology. 39:121-137
This is partly a review and partly the results of some experimental work. Results for concentrations of trace elements in samples of coal from 9 mines in about 100 km of one seam show the variability in terms of variance ratios, namely, maximum divid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ee84bd80f6355564ff8bd731d2e9e366
https://doi.org/10.1016/0378-3820(94)90176-7
https://doi.org/10.1016/0378-3820(94)90176-7