Zobrazeno 1 - 10
of 434
pro vyhledávání: '"J, Schober"'
Publikováno v:
Journal of Applied Poultry Research, Vol 33, Iss 1, Pp 100384- (2024)
SUMMARY: Light plays a vital role in the visual perception, development, and welfare of birds. Since the advent of LED lights, numerous studies have attempted to obtain the effects of lighting on developing embryos, with quite mixed results. Several
Externí odkaz:
https://doaj.org/article/69709a053d54470ca4dc455c538d368d
Autor:
Anna Josefine von Ofen, Uwe Thiel, Jennifer Eck, Hendrik Gassmann, Melanie Thiede, Julia Hauer, Per Sonne Holm, Sebastian J. Schober
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
Oncolytic viruses (OVs) selectively replicate in tumor cells resulting in lysis, spreading of new infectious units and induction of antitumor immune responses through abrogating an immunosuppressive tumor microenvironment (TME). Due to their mode of
Externí odkaz:
https://doaj.org/article/b4b04f635fa041b693d1f5af12a9aa32
Autor:
Sebastian J. Schober, Melanie Thiede, Hendrik Gassmann, Anna Josefine von Ofen, Pia Knoch, Jennifer Eck, Carolin Prexler, Corazon Kordass-Wally, Julia Hauer, Stefan Burdach, Per Sonne Holm, Uwe Thiel
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundEwing sarcoma (EwS) is an aggressive and highly metastatic bone and soft tissue tumor in pediatric patients and young adults. Cure rates are low when patients present with metastatic or relapsed disease. Therefore, innovative therapy approa
Externí odkaz:
https://doaj.org/article/a52e819a36954a5cb6c30fb713880fa2
Autor:
Jana Koch, Sebastian J. Schober, Sruthi V. Hindupur, Caroline Schöning, Florian G. Klein, Klaus Mantwill, Maximilian Ehrenfeld, Ulrike Schillinger, Timmy Hohnecker, Pan Qi, Katja Steiger, Michaela Aichler, Jürgen E. Gschwend, Roman Nawroth, Per Sonne Holm
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Neither CDK4/6 inhibitors nor oncolytic adenoviruses show high efficiency as monotherapy in the treatment of cancer. Authors show here that when combined, CDK4/6 inhibitors deplete Retinoblastoma protein levels, which leads to more efficient virus re
Externí odkaz:
https://doaj.org/article/6d3245a48baf4eb385f4081c109e6cc7
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Global warming poses detrimental effects on poultry production leading to substantial economic losses. The goal of our experiment was to test the hypothesis that heat stress (HS) would alter welfare and egg quality (EQ) of breeder ducks. Furthermore,
Externí odkaz:
https://doaj.org/article/0f9c2ac442364dd7ab2bfb4600cae122
Autor:
Thomas GP Grünewald, Marta Alonso, Sofia Avnet, Ana Banito, Stefan Burdach, Florencia Cidre‐Aranaz, Gemma Di Pompo, Martin Distel, Heathcliff Dorado‐Garcia, Javier Garcia‐Castro, Laura González‐González, Agamemnon E Grigoriadis, Merve Kasan, Christian Koelsche, Manuela Krumbholz, Fernando Lecanda, Silvia Lemma, Dario L Longo, Claudia Madrigal‐Esquivel, Álvaro Morales‐Molina, Julian Musa, Shunya Ohmura, Benjamin Ory, Miguel Pereira‐Silva, Francesca Perut, Rene Rodriguez, Carolin Seeling, Nada Al Shaaili, Shabnam Shaabani, Kristina Shiavone, Snehadri Sinha, Eleni M Tomazou, Marcel Trautmann, Maria Vela, Yvonne MH Versleijen‐Jonkers, Julia Visgauss, Marta Zalacain, Sebastian J Schober, Andrej Lissat, William R English, Nicola Baldini, Dominique Heymann
Publikováno v:
EMBO Molecular Medicine, Vol 12, Iss 11, Pp 1-33 (2020)
Abstract Sarcomas are heterogeneous and clinically challenging soft tissue and bone cancers. Although constituting only 1% of all human malignancies, sarcomas represent the second most common type of solid tumors in children and adolescents and compr
Externí odkaz:
https://doaj.org/article/32421af97ff64f339c73c8bfd6f57409
Publikováno v:
Public health reports (Washington, D.C. : 1974). 137(5)
Objectives Suicide is a leading cause of death in the United States, and rates vary by race and ethnicity. An analysis of suicide across large US cities is absent from the literature. The objective of this study was to examine suicide rates among the
Autor:
Emilie Biele, Sebastian J. Schober, Carolin Prexler, Melanie Thiede, Kristina von Heyking, Hendrik Gassmann, Jennifer Eck, Busheng Xue, Stefan Burdach, Uwe Thiel
Publikováno v:
Cells, Vol 10, Iss 11, p 3070 (2021)
Ewing’s sarcoma (EwS) is a pediatric solid tumor entity with low somatic mutational burden and a low rate of tumor-infiltrating T cells, indicating a low extent of immunogenicity. In EwS, immunogenicity may furthermore be significantly diminished b
Externí odkaz:
https://doaj.org/article/a017ee78320743c3be409bf39ee9343b
Autor:
Hendrik Gassmann, Kira Schneider, Valentina Evdokimova, Peter Ruzanov, Sebastian J. Schober, Busheng Xue, Kristina von Heyking, Melanie Thiede, Guenther H. S. Richter, Michael W. Pfaffl, Elfriede Noessner, Lincoln D. Stein, Poul H. Sorensen, Stefan E. G. Burdach, Uwe Thiel
Publikováno v:
Cells, Vol 10, Iss 8, p 2081 (2021)
Ewing sarcoma (EwS) is an aggressive pediatric cancer of bone and soft tissues characterized by scant T cell infiltration and predominance of immunosuppressive myeloid cells. Given the important roles of extracellular vesicles (EVs) in cancer-host cr
Externí odkaz:
https://doaj.org/article/c1356498953842378fc022432faf6255
Autor:
Jessica Bishop-Royse, Nazia S. Saiyed, Daniel J. Schober, Emily Laflamme, Brittney S. Lange-Maia, Maria Ferrera, Maureen R. Benjamins
Publikováno v:
Journal of Racial and Ethnic Health Disparities.