Metatranscriptomic analysis indicates prebiotic effect of isomalto/malto-polysaccharides on human colonic microbiota in-vitro

Autor: Klaudyna Borewicz, Bastian Hornung, Fangjie Gu, Pieter H. van der Zaal, Henk A. Schols, Peter J. Schaap, Hauke Smidt

Publikováno v: Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)

Abstract Isomalto/malto-polysaccharides (IMMPs) are a novel type of soluble dietary fibres with a prebiotic potential promoting growth of beneficial microbes in the gut. However, the mode of action of IMMPs remains unknown. Previous studies on IMMPs

Externí odkaz: https://doaj.org/article/75aaa610ba83463785096f112b450a33

Sex differences in cardiovascular complications and mortality in hospital patients with covid-19: registry based observational study

Autor: Sanne A E Peters, Mark Woodward, Fw Asselbergs, Folkert W Asselbergs, B Williams, GP McCann, R Zaal, Carinna Hockham, P Dark, S Prasad, A Aujayeb, A Mosterd, M Saxena, L Gabriel, CE Delsing, J De Sutter, R Pisters, P van der Meer, M Caputo, A Schut, P van der Harst, MT Kearney, YM Pinto, DP Ripley, RG Tieleman, J Redón, A Moriarty, P Woudstra, Marijke Linschoten, G Captur, Chahinda Ghossein, AK Al-Ali, FA Al-Muhanna, NYY Al-Windy, YA Almubarak, AN Alnafie, M Alshahrani, AM Alshehri, RL Anthonio, JM ten Berg, AJM van Boxem, N Charlotte, HGR Dorman, JT Drost, ME Emans, JB Ferreira, WH van Gilst, BE Groenemeijer, HE Haerkens-Arends, B Hedayat, DJ van der Heijden, E Hellou, RS Hermanides, JF Hermans-van Ast, MWJ van Hessen, SRB Heymans, ICC van der Horst, SH van Ierssel, LS Jewbali, HAM van Kesteren, Kietselaer BLJH, AMH Koning, PY Kopylov, AFM Kuijper, JM Kwakkel-vanErp, van der Linden MMJM, M Linschoten, GCM Linssen, Macias Ruiz R, FJH Magdelijns, Martens FMAC, MFL Meijs, P Messiaen, PS Monraats, L Montagna, PR Nierop, CEE van Ofwegen-Hanekamp, H Poorhosseini, AC Reidinga, MIA Ribeiro, R Salah, E Saneei, J Schaap, Schellings DAAM, A Shafiee, AC Shore, HJ Siebelink, M van Smeden, PC Smits, E Tessitore, P Timmermans, RA Tio, FVY Tjong, CA den Uil, EM Van Craenenbroeck, van Veen HPAA, T Veneman, DO Verschure, JK de Vries, RMA van de Wal, DJ van de Watering, ICD Westendorp, PHM Westendorp, C Weytjens, E Wierda, KW Wu, AG Zaman, PM van derZee

Publikováno v: BMJ Medicine, Vol 2, Iss 1 (2023)

Objective To assess whether the risk of cardiovascular complications of covid-19 differ between the sexes and to determine whether any sex differences in risk are reduced in individuals with pre-existing cardiovascular disease.Design Registry based o

Externí odkaz: https://doaj.org/article/b7d0598755264004ab8a236f850ae4a9

Classification of the plant-associated lifestyle of Pseudomonas strains using genome properties and machine learning

Autor: Wasin Poncheewin, Anne D. van Diepeningen, Theo A. J. van der Lee, Maria Suarez-Diez, Peter J. Schaap

Publikováno v: Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)

Abstract The rhizosphere, the region of soil surrounding roots of plants, is colonized by a unique population of Plant Growth Promoting Rhizobacteria (PGPR). Many important PGPR as well as plant pathogens belong to the genus Pseudomonas. There is, ho

Externí odkaz: https://doaj.org/article/00e7090c94294239b16e4d4520732c08

Factors associated with use of community-based, peer-led sexual and reproductive health services by adolescent boys and young men aged 18-24 in Lusaka, Zambia: A case control study nested in the Yathu Yathu trial.

Autor: Mwelwa M Phiri, Bernadette Hensen, Lucheka M Sigande, Sian Floyd, Albertus J Schaap, Melvin Simuyaba, Lawrence Mwenge, Rosemary Zulu-Phiri, Louis Mwape, Sarah Fidler, Musonda Simwinga, Richard Hayes, Helen M Ayles

Publikováno v: PLOS Global Public Health, Vol 3, Iss 11, p e0002446 (2023)

IntroductionAdolescents and young people (AYP) aged 15-24 years have the least access to facility-based sexual and reproductive health (SRH) services, including HIV services. The Yathu-Yathu cluster-randomized trial (CRT) in Zambia tested whether a n

Externí odkaz: https://doaj.org/article/afd3bf8237c2460a9f532a6ceb9c9299

Genomic convergence between Akkermansia muciniphila in different mammalian hosts

Autor: Sharon Y. Geerlings, Janneke P. Ouwerkerk, Jasper J. Koehorst, Jarmo Ritari, Steven Aalvink, Bärbel Stecher, Peter J. Schaap, Lars Paulin, Willem M. de Vos, Clara Belzer

Publikováno v: BMC Microbiology, Vol 21, Iss 1, Pp 1-13 (2021)

Abstract Background Akkermansia muciniphila is a member of the human gut microbiota where it resides in the mucus layer and uses mucin as the sole carbon, nitrogen and energy source. A. muciniphila is the only representative of the Verrucomicrobia ph

Externí odkaz: https://doaj.org/article/49596201ae2043a989d408fbd7a0aebc