Zobrazeno 1 - 10
of 1 293
pro vyhledávání: '"J, Sanyal"'
Autor:
Bani Mukhopadhyay, Cheryl Marietta, Pei-Hong Shen, Abdul Oiseni, Faridoddin Mirshahi, Maria Mazzu, Colin Hodgkinson, Eli Winkler, Qiaoping Yuan, Daniel Miranda, George Kunos, Arun J. Sanyal, David Goldman
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Only ~20% of heavy drinkers develop alcohol cirrhosis (AC). While differences in metabolism, inflammation, signaling, microbiome signatures and genetic variations have been tied to the pathogenesis of AC, the key underlying mechanisms for th
Externí odkaz:
https://doaj.org/article/5e94a80be9ff4499a96a3e21c2c7338e
Autor:
Arun J. Sanyal, Mansoor Husain, Crystel Diab, Kamal Kant Mangla, Ahsan Shoeb, Ildiko Lingvay, Elliot B. Tapper
Publikováno v:
American Heart Journal Plus, Vol 41, Iss , Pp 100386- (2024)
The burden of cardiovascular disease (CVD) in patients with metabolic dysfunction-associated steatohepatitis (MASH) is poorly characterized, particularly vs other liver diseases including metabolic dysfunction-associated steatotic liver disease (MASL
Externí odkaz:
https://doaj.org/article/8978dd97a7c94b9cb98a54820240fa6c
Autor:
Quentin M. Anstee, Jeremy Magnanensi, Yacine Hajji, Alexandra Caron, Zouher Majd, Christian Rosenquist, Dean W. Hum, Bart Staels, Margery A. Connelly, Rohit Loomba, Stephen A. Harrison, Vlad Ratziu, Arun J. Sanyal
Publikováno v:
JHEP Reports, Vol 6, Iss 4, Pp 101011- (2024)
Background & Aims: Robust performance of non-invasive tests (NITs) across ages is critical to assess liver disease among patients with metabolic dysfunction-associated liver disease (MASLD). We evaluated the impact of age on the performance of NIS2+
Externí odkaz:
https://doaj.org/article/e823e08beef848c0a1ad7f05022bf9e3
Autor:
Philip N. Newsome, Arun J. Sanyal, Guy Neff, Jörn M. Schattenberg, Vlad Ratziu, Judith Ertle, Jasmin Link, Alison Mackie, Corinna Schoelch, Eric Lawitz, BI 1467335 NASH Phase IIa trial team
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-11 (2023)
Abstract Non-alcoholic steatohepatitis (NASH) is a progressive, inflammatory liver disease with no approved pharmacological treatment. This Phase IIa, double-blind, placebo-controlled, multicentre trial (ClinicalTrials.gov: NCT03166735) investigated
Externí odkaz:
https://doaj.org/article/f8f75d8f1dd9428aae4a8f04531f0a04
Publikováno v:
American Journal of Preventive Cardiology, Vol 17, Iss , Pp 100638- (2024)
Metabolic-dysfunction associated steatotic liver disease (MASLD) affects 1 out of every 3 individuals in the adult population and the disease prevalence is predicted to increase worldwide. Patients with MASLD are also burdened by cardiovascular disea
Externí odkaz:
https://doaj.org/article/754ef48711844676b255eaa7d3012383
Autor:
Mary E. Rinella, Jeffrey V. Lazarus, Vlad Ratziu, Sven M. Francque, Arun J. Sanyal, Fasiha Kanwal, Diana Romero, Manal F. Abdelmalek, Quentin M. Anstee, Juan Pablo Arab, Marco Arrese, Ramon Bataller, Ulrich Beuers, Jerome Boursier, Elisabetta Bugianesi, Christopher D. Byrne, Graciela E. Castro Narro, Abhijit Chowdhury, Helena Cortez-Pinto, Donna R. Cryer, Kenneth Cusi, Mohamed El-Kassas, Samuel Klein, Wayne Eskridge, Jiangao Fan, Samer Gawrieh, Cynthia D. Guy, Stephen A. Harrison, Seung Up Kim, Bart G. Koot, Marko Korenjak, Kris V. Kowdley, Florence Lacaille, Rohit Loomba, Robert Mitchell-Thain, Timothy R. Morgan, Elisabeth E. Powell, Michael Roden, Manuel Romero-Gómez, Marcelo Silva, Shivaram Prasad Singh, Silvia C. Sookoian, C. Wendy Spearman, Dina Tiniakos, Luca Valenti, Miriam B. Vos, Vincent Wai-Sun Wong, Stavra Xanthakos, Yusuf Yilmaz, Zobair Younossi, Ansley Hobbs, Marcela Villota-Rivas, Philip N. Newsome
Publikováno v:
Annals of Hepatology, Vol 29, Iss 1, Pp 101133- (2024)
The principal limitations of the terms NAFLD and NASH are the reliance on exclusionary confounder terms and the use of potentially stigmatising language. This study set out to determine if content experts and patient advocates were in favor of a chan
Externí odkaz:
https://doaj.org/article/f02c612b79da4aaa8837228f72393227
Autor:
Nicholas Koelsch, Faridoddin Mirshahi, Hussein F. Aqbi, Mulugeta Saneshaw, Michael O. Idowu, Amy L. Olex, Arun J. Sanyal, Masoud H. Manjili
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-18 (2023)
Abstract Abundance of data on the role of inflammatory immune responses in the progression or inhibition of hepatocellular carcinoma (HCC) has failed to offer a curative immunotherapy for HCC. This is largely because of focusing on detailed specific
Externí odkaz:
https://doaj.org/article/b445faca8cc44241a8a690ae830ee44f
Autor:
Vardhmaan Jain, Anurag Mehta, Terence B. Lee, Chang Liu, Nicholas W. S. Chew, Yi‐An Ko, Matthew E. Gold, Daniel A. Gold, Nishant Vatsa, Shivang R. Desai, Jonathan H. Kim, Alireza Rahbar, Yazan Haroun, Kiran Ejaz, Salim S. Hayek, Mohammad S. Siddiqui, Fadi N. Salloum, Laurence S. Sperling, Arun J. Sanyal, Arshed A. Quyyumi
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 12, Iss 24 (2023)
Background Literature suggests a bidirectional association between advanced hepatic fibrosis (AHF) and coronary artery disease (CAD). We evaluated the association of AHF with immune activation, systemic inflammation, and adverse outcomes in patients
Externí odkaz:
https://doaj.org/article/47a6d0767efe4de38824653f4cbda91c
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Background and aimsIdentification of high-risk patients for hepatocellular carcinoma (HCC) is essential for long term monitoring of nonalcoholic steatohepatitis (NASH) cirrhosis progression. We sought to evaluate the association between Fibrosis-4 (F
Externí odkaz:
https://doaj.org/article/ccd79d181f564670a28754fda0c56e63
Autor:
Volodymyr P. Tryndyak, Rose A. Willett, Mark I. Avigan, Arun J. Sanyal, Frederick A. Beland, Ivan Rusyn, Igor P. Pogribny
Publikováno v:
Epigenetics, Vol 17, Iss 11, Pp 1462-1476 (2022)
Non-alcoholic fatty liver disease (NAFLD) is a highly prevalent chronic liver disease, and patient susceptibility to its onset and progression is influenced by several factors. In this study, we investigated whether altered hepatic DNA methylation in
Externí odkaz:
https://doaj.org/article/c8f998f36f854dbc86f10cb401c5e178