MRAP2 regulates ghrelin receptor signaling and hunger sensing

Autor: Dollada Srisai, Terry C. Yin, Abigail A. Lee, Alix A. J. Rouault, Nicole A. Pearson, Justin L. Grobe, Julien A. Sebag

Publikováno v: Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)

Melanocortin receptor accessory protein 2 (MRAP2) is an adaptor protein that contributes to melanocortin-4 receptor and prokineticin receptor 1 signalling. Here the authors show that MRAP2 also regulates ghrelin receptor signalling in the hypothalamu

Externí odkaz: https://doaj.org/article/0c8ac5f69f6445bd9e9a8456fe6f8bef

Regions of MRAP2 required for the inhibition of orexin and prokineticin receptor signaling

Autor: Abigail A. Lee, Alix A. J. Rouault, Julien A. Sebag

Publikováno v: Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1864:2322-2329

The Melanocortin Receptor Accessory Protein 2 (MRAP2) regulates the activity of several GPCRs involved in the control of food intake and energy expenditure. While MRAP2 was originally thought to exclusively interact with melanocortin receptors we hav

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcfda53505e4837cbd616f9a86e55129
https://doi.org/10.1016/j.bbamcr.2017.09.008

MRAP2 regulates ghrelin receptor signaling and hunger sensing

Autor: Nicole A Pearson, Justin L. Grobe, Dollada Srisai, Julien A. Sebag, Abigail A. Lee, Terry C. Yin, Alix A. J. Rouault

Publikováno v: Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
Nature Communications

Ghrelin is the only known circulating orexigenic hormone. It is primarily secreted by the stomach and acts at its receptor, the growth hormone secretagogue receptor 1a (GHSR1a), in the hypothalamus to signal hunger and promote food intake. The melano

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e6f68373f4e6bea100b18174f647292
http://link.springer.com/article/10.1038/s41467-017-00747-6

Wind changes above warm Agulhas Current eddies

Autor: Bjorn-Christoph Backeberg, Marjolaine J Rouault, P. Verley

Publikováno v: Ocean Science, Vol 12, Iss 2, Pp 495-506 (2016)
Ocean Science
Ocean Science, European Geosciences Union, 2016, 12 (2), pp.495-506. ⟨10.5194/os-12-495-2016⟩
Ocean Science, 2016, 12 (2), pp.495-506. ⟨10.5194/os-12-495-2016⟩

Sea surface temperature (SST) estimated from the Advanced Microwave Scanning Radiometer E onboard the Aqua satellite and altimetry-derived sea level anomalies are used south of the Agulhas Current to identify warm-core mesoscale eddies presenting a d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a62dbb60f50d7ed9dc6b67f2909634cb
https://doi.org/10.5194/os-12-495-2016

FRENCH PROGRAM TOWARDS AN INNOVATIVE SODIUM COOLED FAST REACTOR

Autor: Ph. Martin, Jean-Pol Serpantie, D. Verwaerde, J. Rouault, P. Anzieu

Publikováno v: Nuclear Engineering and Technology. 39:237-248

Sodium-cooled fast reactor is considered in France as a potential candidate for a prototype of 4th generation system to be built by 2020. A detailed working program has been launched recently to identify by 2012 the potential improvement tracks for l

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b1a205a82b4efea9eff29dab3f2d729a
https://doi.org/10.5516/net.2007.39.4.237