Zobrazeno 1 - 10
of 1 073
pro vyhledávání: '"J, Plant"'
Autor:
Barry J Plant, Daniel Peckham, Pierre-Régis Burgel, Alan Smyth, Andreas Jung, Manfred Ballmann, Giovanni Taccetti, Harry Heijerman, Pavel Drevinek, Jochen G Mainz, Carsten Schwarz
Publikováno v:
BMJ Open Respiratory Research, Vol 11, Iss 1 (2024)
The major cause of mortality in people with cystic fibrosis (pwCF) is progressive lung disease characterised by acute and chronic infections, the accumulation of mucus, airway inflammation, structural damage and pulmonary exacerbations. The prevalenc
Externí odkaz:
https://doaj.org/article/ce777e645bdb4ad08771fda0a6783f30
Autor:
Desmond M Murphy, B J Plant, Joseph A Eustace, Parniya Arooj, David V Morrissy, Yvonne McCarthy, Tamara Vagg, Mairead McCarthy, Claire Fleming, Mary Daly
Publikováno v:
BMJ Open Respiratory Research, Vol 10, Iss 1 (2023)
Background Previous studies showed that the combination of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) corrector and potentiator, lumacaftor–ivacaftor (LUMA–IVA) provides meaningful clinical benefits in patients with cystic fibrosi
Externí odkaz:
https://doaj.org/article/49db3130031441878d029412e4fb451a
Autor:
Tamara Vagg, Kevin F. Deasy, Wendy W. Chapman, Sarath C. Ranganathan, Barry J. Plant, Shivanthan Shanthikumar
Publikováno v:
Frontiers in Digital Health, Vol 5 (2023)
Cystic Fibrosis (CF) is a chronic life-limiting condition that affects multiple organs within the body. Patients must adhere to strict medication regimens, physiotherapy, diet, and attend regular clinic appointments to manage their condition effectiv
Externí odkaz:
https://doaj.org/article/85920afba5784ed5bd84b68844a4efda
Autor:
Hisham Ibrahim, Hammad Danish, David Morrissey, Kevin F. Deasy, Mairead McCarthy, James Dorgan, Claire Fleming, Ciara Howlett, Sarah Twohig, Tamara Vagg, Desmond M. Murphy, Michael Maher, Barry J. Plant
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
The prevalence of mental health disorders is high among people with Cystic Fibrosis. The psychological symptoms in CF are associated with poor adherence, worse treatment outcomes, and greater health utilization/cost. Mental health and neurocognitive
Externí odkaz:
https://doaj.org/article/7bb23dea61d344e0b8319f6455ac143b
MicroRNA regulatory networks associated with abnormal muscle repair in survivors of critical illness
Autor:
Christopher J. Walsh, Carlos Escudero King, Muskan Gupta, Pamela J. Plant, Margaret J. Herridge, Sunita Mathur, Pingzhao Hu, Judy Correa, Sameen Ahmed, Anne Bigot, Claudia C. dosSantos, Jane Batt, Submitted on behalf of the MusclE and Nerve Dysfunction (MEND)‐ICU Group and Canadian Critical Care Translational Biology Group (CCCTBG)
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 13, Iss 2, Pp 1262-1276 (2022)
Abstract Background Intensive care unit (ICU)‐acquired weakness is characterized by muscle atrophy and impaired contractility that may persist after ICU discharge. Dysregulated muscle repair and regeneration gene co‐expression networks are presen
Externí odkaz:
https://doaj.org/article/f8215a3d765742de99fa1db9d3550ea5
Autor:
Laura J. Walsh, Deborah Casey, Punitha Vairamani, Fiona Arnott, Barry J. Plant, Desmond M. Murphy
Publikováno v:
Frontiers in Allergy, Vol 3 (2023)
IntroductionApproximately 3%–10% of asthma patients will remain uncontrolled despite maximum, optimal conventional therapy. Treatment of severe refractory asthma often involves the use of targeted biological therapy. Randomised controlled trials ha
Externí odkaz:
https://doaj.org/article/5a30f0b80bdb47e7872ebaaa797dc871
Autor:
Aoife M. Rodgers, Jaime Lindsay, Avril Monahan, Alice V. Dubois, Aduragbemi A. Faniyi, Barry J. Plant, Marcus A. Mall, Miquel B. Ekkelenkamp, Stuart Elborn, Rebecca J. Ingram
Publikováno v:
Pathogens, Vol 12, Iss 8, p 1053 (2023)
Pseudomonas aeruginosa (P. aeruginosa) is an opportunistic pathogen and the leading cause of infection in patients with cystic fibrosis (CF). The ability of P. aeruginosa to evade host responses and develop into chronic infection causes significant m
Externí odkaz:
https://doaj.org/article/ef0e5f92a6e44709bee52bd0568285e4
Publikováno v:
Therapeutic Advances in Respiratory Disease, Vol 16 (2022)
Externí odkaz:
https://doaj.org/article/6801d5800058415da6af4843de1b3157
Autor:
Dave Kharas, Jason J. Plant, William Loh, Reuel B. Swint, Suraj Bramhavar, Christopher Heidelberger, Siva Yegnanarayanan, Paul W. Juodawlkis
Publikováno v:
IEEE Photonics Journal, Vol 12, Iss 6, Pp 1-12 (2020)
We demonstrate a high-power on-chip 1550-nm laser implemented by passive flip-chip integration of a curved-channel, double-pass InGaAsP/InP slab-coupled optical waveguide amplifier (SCOWA) onto a photonic integrated circuit (PIC) containing a silicon
Externí odkaz:
https://doaj.org/article/e0fc32f4191a4a1799d3a1151bc6e58d
Autor:
Alexander J. Plant-Hately, Burcu Eryilmaz, Christopher A. W. David, Danielle E. Brain, Bethany J. Heaton, Yvonne Perrie, Neill J. Liptrott
Publikováno v:
Pharmaceutics, Vol 14, Iss 11, p 2470 (2022)
Lipidic nanoparticles (LNP), particularly liposomes, have been proven to be a successful and versatile platform for intracellular drug delivery for decades. Whilst primarily developed for small molecule delivery, liposomes have recently undergone a r
Externí odkaz:
https://doaj.org/article/f085aa3173a5414e81b0a43696c6b45f