Zobrazeno 1 - 10
of 1 341
pro vyhledávání: '"J, Pemberton"'
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss Suppl 1 (2024)
Externí odkaz:
https://doaj.org/article/9223fa63d45a455e84e40139c27bec72
Autor:
Sarah Appleby, Chris Frampton, Mark Holdaway, Janice Chew-Harris, Oi Wah Liew, Jenny Pek Ching Chong, Lynley Lewis, Richard Troughton, Shirley Beng Suat Ooi, Win Sen Kuan, Irwani Ibrahim, Siew Pang Chan, A. Mark Richards, Christopher J. Pemberton
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 10 (2024)
ObjectivesIn dyspneic patients with atrial fibrillation (AF) or obesity, the diagnostic performance of NT-proBNP for acute heart failure is reduced. We evaluated the erythroblast derived protein erythroferrone (ERFE) as an ancillary biomarker for the
Externí odkaz:
https://doaj.org/article/d4bf2deab49841a8941b326c600529d7
Autor:
Moritz Lassé, Anna P. Pilbrow, Torsten Kleffmann, Elin Andersson Överström, Anne von Zychlinski, Christopher M. A. Frampton, Katrina K. Poppe, Richard W. Troughton, Lynley K. Lewis, Timothy C. R. Prickett, Christopher J. Pemberton, Arthur M. Richards, Vicky A. Cameron
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract To identify circulating proteins predictive of acute cardiovascular disease events in the general population, we performed a proteomic screen in plasma from asymptomatic individuals. A “Discovery cohort” of 25 individuals who subsequentl
Externí odkaz:
https://doaj.org/article/043710be91bb407197c17d86d6c4b4e8
Autor:
Kai M Eggers, Ola Hammarsten, Sally J Aldous, Louise Cullen, Jaimi H Greenslade, Bertil Lindahl, William A Parsonage, Christopher J Pemberton, John W Pickering, A Mark Richards, Richard W Troughton, Martin P Than
Publikováno v:
PLoS ONE, Vol 17, Iss 11, p e0276645 (2022)
BackgroundElevations of high-sensitivity cardiac troponin (hs-cTn) concentrations not related to type 1 myocardial infarction are common in chest pain patients presenting to emergency departments. The discrimination of these patients from those with
Externí odkaz:
https://doaj.org/article/8b9f8d8ee7a74a709742890a1e5c5ca5
Autor:
Barry R Palmer, Melinda A Paterson, Chris M Frampton, Anna P Pilbrow, Lorraine Skelton, Chris J Pemberton, Robert N Doughty, Chris J Ellis, Richard W Troughton, A Mark Richards, Vicky A Cameron
Publikováno v:
PLoS ONE, Vol 16, Iss 7, p e0254206 (2021)
BackgroundDevelopment of a competent collateral circulation in established coronary artery disease is cardio-protective. The vascular endothelial growth factor (VEGF) system plays a key role in this process. We investigated the prognostic performance
Externí odkaz:
https://doaj.org/article/6fa3494f411c4b08af18bcb3f58ba37b
Autor:
Edward C. A. Marks, Tom M. Wilkinson, Chris M. Frampton, Lorraine Skelton, Anna P. Pilbrow, Tim G. Yandle, Chris J. Pemberton, Robert N. Doughty, Gillian A. Whalley, Chris J. Ellis, Richard W. Troughton, Maurice C. Owen, Neil R. Pattinson, Vicky A. Cameron, A. Mark Richards, Steven P. Gieseg, Barry R. Palmer
Publikováno v:
BMC Cardiovascular Disorders, Vol 18, Iss 1, Pp 1-10 (2018)
Abstract Background Development of collateral circulation in coronary artery disease is cardio-protective. A key process in forming new blood vessels is attraction to occluded arteries of monocytes with their subsequent activation as macrophages. In
Externí odkaz:
https://doaj.org/article/01714fa83ef840fd816739c6fcf31fa9
Autor:
Jelle Praet, Nikolay V. Manyakov, Leacky Muchene, Zhenhua Mai, Vasilis Terzopoulos, Steve de Backer, An Torremans, Pieter-Jan Guns, Tom Van De Casteele, Astrid Bottelbergs, Bianca Van Broeck, Jan Sijbers, Dirk Smeets, Ziv Shkedy, Luc Bijnens, Darrel J. Pemberton, Mark E. Schmidt, Annemie Van der Linden, Marleen Verhoye
Publikováno v:
Alzheimer’s Research & Therapy, Vol 10, Iss 1, Pp 1-16 (2018)
Abstract Background Alzheimer’s disease (AD) is a progressive neurodegenerative disorder and the most common cause of dementia in the elderly population. In this study, we used the APP/PS1 transgenic mouse model to explore the feasibility of using
Externí odkaz:
https://doaj.org/article/2e0e17af4d50440b83a9140322f6cfeb
Publikováno v:
BMC Genomics, Vol 18, Iss 1, Pp 1-33 (2017)
Abstract Background Genomic regions of autozygosity (ROA) arise when an individual is homozygous for haplotypes inherited identical-by-descent from ancestors shared by both parents. Over the past decade, they have gained importance for understanding
Externí odkaz:
https://doaj.org/article/c500c420e60e419eb4c8d636928f3511
Autor:
Lynley K, Lewis, Sara D, Raudsepp, Joanna C, Whitlow, Sarah, Appleby, Christopher J, Pemberton, Timothy G, Yandle, A, Mark Richards
Publikováno v:
Clinical Chemistry. 68:1292-1301
Background Secretion of cardioprotective B-type natriuretic peptide 1–32 (BNP1-32) is increased proportionately with cardiac dysfunction, but its measurement in plasma is difficult. Therefore, less specific BNP and amino-terminal proBNP (NT-proBNP)
Autor:
Ashwin N Ananthakrishnan, Gilaad G Kaplan, Charles N Bernstein, Kristin E Burke, Paul J Lochhead, Alexa N Sasson, Manasi Agrawal, Jimmy Ho Tuan Tiong, Joshua Steinberg, Wolfgang Kruis, Flavio Steinwurz, Vineet Ahuja, Siew C Ng, David T Rubin, Jean-Frederic Colombel, Richard Gearry, M Abreu, V Ahuja, M Allez, A Ananthakrishnan, W Bemelman, C Bernstein, J Braun, Y Chowers, J-F Colombel, S Danese, G D'Haens, A D'Hoore, A Dignass, I Dotan, M Dubinsky, A Ekbom, P Fleshner, C Gasche, MA Gassull, R Gearry, S Ghosh, P Gibson, A Griffiths, J Halfvarson, S Hanauer, N Harpaz, A Hart, T Hibi, M Kamm, G Kaplan, A Kaser, B Korelitz, P Kotze, I Koutroubakis, W Kruis, P Lakatos, J Lewis, J Lindsay, E Loftus, E Louis, M Lukas, F Magro, U Mahadevan, G Mantzaris, J-Y Mary, D McGovern, B Moum, P Munkholm, M Neurath, S Ng, C O'Morain, T Oresland, R Panaccione, J Panes, Y Panis, J Pemberton, L Peyrin-Biroulet, C Prantera, D Rachmilewitz, Z Ran, W Reinisch, F Remzi, J Rhodes, R Riddell, G Rogler, D Rubin, D Sachar, W Sandborn, B Sands, B Sartor, J Schoelmerich, S Schreiber, C Siegel, B Siegmund, M Silverberg, J Söderholm, A Sood, A Spinelli, E Stange, F Steinwurz, S Targan, S Travis, D Turner, C Tysk, M Vatn, S Vermeire, M Watanabe, T Yamamoto, J Yamamoto-Furusho
Publikováno v:
Ananthakrishnan, A N, Kaplan, G G, Bernstein, C N, Burke, K E, Lochhead, P J, Sasson, A N, Agrawal, M, Tiong, J H T, Steinberg, J, Kruis, W, Steinwurz, F, Ahuja, V, Ng, S C, Rubin, D T, Colombel, J-F, Gearry, R & International Organization for Study of Inflammatory Bowel Diseases 2022, ' Lifestyle, behaviour, and environmental modification for the management of patients with inflammatory bowel diseases : an International Organization for Study of Inflammatory Bowel Diseases consensus ', The Lancet Gastroenterology & Hepatology, vol. 7, no. 7, pp. 666-678 . https://doi.org/10.1016/S2468-1253(22)00021-8
Environmental and lifestyle factors play an important role in the natural history of Crohn's disease and ulcerative colitis. A group of international experts from the International Organization for the Study of Inflammatory Bowel Diseases voted on a