Zobrazeno 1 - 10
of 2 762
pro vyhledávání: '"J, Otto"'
Autor:
Derek H. Janssens, Melodie Duran, Dominik J. Otto, Weifang Wu, Yiling Xu, Danielle Kirkey, Charles G. Mullighan, Joanna S. Yi, Soheil Meshinchi, Jay F. Sarthy, Kami Ahmad, Steven Henikoff
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Chromosomal translocations involving the mixed-lineage leukemia (MLL) locus generate potent oncogenic fusion proteins (oncoproteins) that disrupt regulation of developmental gene expression. By profiling the oncoprotein-target sites of 36 br
Externí odkaz:
https://doaj.org/article/ea636cfdd021408692f0ace826848682
Publikováno v:
JSES Reviews, Reports, and Techniques, Vol 4, Iss 2, Pp 253-260 (2024)
Externí odkaz:
https://doaj.org/article/58024dd77ec04f09a934e6db6cde20eb
Autor:
Chang-Ching Lin, Tsung-Cheng Chang, Yunguan Wang, Lei Guo, Yunpeng Gao, Emmanuel Bikorimana, Andrew Lemoff, Yisheng V. Fang, He Zhang, Yanfeng Zhang, Dan Ye, Isabel Soria-Bretones, Alberto Servetto, Kyung-min Lee, Xuemei Luo, Joseph J. Otto, Hiroaki Akamatsu, Fabiana Napolitano, Ram Mani, David W. Cescon, Lin Xu, Yang Xie, Joshua T. Mendell, Ariella B. Hanker, Carlos L. Arteaga
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract CDK4/6 inhibitors (CDK4/6i) have improved survival of patients with estrogen receptor-positive (ER+) breast cancer. However, patients treated with CDK4/6i eventually develop drug resistance and progress. RB1 loss-of-function alterations conf
Externí odkaz:
https://doaj.org/article/e4a5c7d11ac44ac3ba09402a88d94d20
Autor:
Sebastian J. Otto, Laura Teichmann, Niklas Fante, Peter Crauwels, Alexander Grünberger, Tobias Neddermann, Christian U. Riedel
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 12 (2024)
The global increase in antibiotic resistances demands for additional efforts to identify novel antimicrobials such as bacteriocins. These antimicrobial peptides of bacterial origin are already used widely in food preservation and promising alternativ
Externí odkaz:
https://doaj.org/article/89469dfd313f4d288f2b115fbb26d8d6
Autor:
Michael Rade, Markus Kreuz, Angelika Borkowetz, Ulrich Sommer, Conny Blumert, Susanne Füssel, Catharina Bertram, Dennis Löffler, Dominik J. Otto, Livia A. Wöller, Carolin Schimmelpfennig, Ulrike Köhl, Ann-Cathrin Gottschling, Pia Hönscheid, Gustavo B. Baretton, Manfred Wirth, Christian Thomas, Friedemann Horn, Kristin Reiche
Publikováno v:
Molecular Medicine, Vol 30, Iss 1, Pp 1-20 (2024)
Abstract Background Clinical manifestation of prostate cancer (PCa) is highly variable. Aggressive tumors require radical treatment while clinically non-significant ones may be suitable for active surveillance. We previously developed the prognostic
Externí odkaz:
https://doaj.org/article/c464d6da04a84fa9b2ebac3773083177
Autor:
Kyle P. O’Sullivan, Brian J. Philip, Jonathan L. Baker, John D. Rolston, Mark E. Orazem, Kevin J. Otto, Christopher R. Butson
Publikováno v:
Data, Vol 9, Iss 6, p 78 (2024)
Invasive intracranial electrodes are used in both clinical and research applications for recording and stimulation of brain tissue, providing essential data in acute and chronic contexts. The impedance characteristics of the electrode–tissue interf
Externí odkaz:
https://doaj.org/article/9a15c5a2e0a8493b9f9399ed8b2f4ec4
Autor:
Rasmus, Sirpa, Yletyinen, Johanna, Sarkki, Simo, Landauer, Mia, Tuomi, Maria, Arneberg, Marit K., Bjerke, Jarle W., Ehrich, Dorothee, Habeck, J. Otto, Horstkotte, Tim, Kivinen, Sonja, Komu, Teresa, Kumpula, Timo, Leppänen, Leena, Matthes, Heidrun, Rixen, Christian, Stark, Sari, Sun, Ningning, Tømmervik, Hans, Forbes, Bruce C., Eronen, Jussi T.
Publikováno v:
In One Earth 16 February 2024 7(2):265-279
Publikováno v:
Bioelectronic Medicine, Vol 9, Iss 1, Pp 1-13 (2023)
Abstract Background The purpose of this study was to evaluate if kilohertz frequency alternating current (KHFAC) stimulation of peripheral nerve could serve as a treatment for lumbar radiculopathy. Prior work shows that KHFAC stimulation can treat sc
Externí odkaz:
https://doaj.org/article/d67a9e4c4999440eb44e591aaec264b6
Autor:
Carolin Schimmelpfennig, Michael Rade, Susanne Füssel, Dennis Löffler, Conny Blumert, Catharina Bertram, Angelika Borkowetz, Dominik J. Otto, Sven-Holger Puppel, Pia Hönscheid, Ulrich Sommer, Gustavo B. Baretton, Ulrike Köhl, Manfred Wirth, Christian Thomas, Friedemann Horn, Markus Kreuz, Kristin Reiche
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-20 (2023)
Abstract Background Prostate cancer (PCa) is one of the most prevalent cancers worldwide. The clinical manifestations and molecular characteristics of PCa are highly variable. Aggressive types require radical treatment, whereas indolent ones may be s
Externí odkaz:
https://doaj.org/article/33f9e042a8f748879f7f4908f10f205d
Autor:
J. Otto Pohl
Publikováno v:
Kulturní Studia, Vol 2, Iss 2022, Pp 93-106 (2022)
Soviet policy towards its Kurdish minority shifted from supporting their cultural development during the 1920s and early 1930s to a more repressive policy from 1937-1956 and then back again to a more favorable position. Soviet repression of its Kurdi
Externí odkaz:
https://doaj.org/article/0a47cf5420f441f68b382d09450eb4b6