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Akademický článek

Results of a randomized, double-blind phase II clinical trial of NY-ESO-1 vaccine with ISCOMATRIX adjuvant versus ISCOMATRIX alone in participants with high-risk resected melanoma

Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 8, Iss 1 (2020)

Background To compare the clinical efficacy of New York Esophageal squamous cell carcinoma-1 (NY-ESO-1) vaccine with ISCOMATRIX adjuvant versus ISCOMATRIX alone in a randomized, double-blind phase II study in participants with fully resected melanoma

Externí odkaz: https://doaj.org/article/180a81075c10497e8c8ac926325f3b4e

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Data from Nonclassical Antigen-Processing Pathways Are Required for MHC Class II–Restricted Direct Tumor Recognition by NY-ESO-1–Specific CD4+ T Cells

Autor: Kunle Odunsi, Sacha Gnjatic, Protul Shrikant, Lloyd J. Old, Immanuel Luescher, Takemasa Tsuji, Junko Matsuzaki

Tumor antigen–specific CD4+ T cells that directly recognize cancer cells are important for orchestrating antitumor immune responses at the local tumor sites. However, the mechanisms of direct MHC class II (MHC-II) presentation of intracellular tumo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::cf1fcc980266480f1e49e40a602e6b8b
https://doi.org/10.1158/2326-6066.c.6548809.v1

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Supplementary Figure 3 from Nonclassical Antigen-Processing Pathways Are Required for MHC Class II–Restricted Direct Tumor Recognition by NY-ESO-1–Specific CD4+ T Cells

Autor: Kunle Odunsi, Sacha Gnjatic, Protul Shrikant, Lloyd J. Old, Immanuel Luescher, Takemasa Tsuji, Junko Matsuzaki

PDF file - 152K, MHC class II antigen presentation pathway of intracellular NY-ESO-1 by SK-MEL-37.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30c752a1cfe9a6b556da52dd80f7075a
https://doi.org/10.1158/2326-6066.22538542.v1

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Supplementary Figure 2 from Nonclassical Antigen-Processing Pathways Are Required for MHC Class II–Restricted Direct Tumor Recognition by NY-ESO-1–Specific CD4+ T Cells

Autor: Kunle Odunsi, Sacha Gnjatic, Protul Shrikant, Lloyd J. Old, Immanuel Luescher, Takemasa Tsuji, Junko Matsuzaki

PDF file - 97K, Effect of IFN-gamma treatment of HLA-DP4+ melanoma cell lines on intracellular NY-ESO-1 to TR-CD4.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06b01ae7dc4cf297fb6158f04f9676a2
https://doi.org/10.1158/2326-6066.22538545

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Supplementary Figure 1 from Nonclassical Antigen-Processing Pathways Are Required for MHC Class II–Restricted Direct Tumor Recognition by NY-ESO-1–Specific CD4+ T Cells

Autor: Kunle Odunsi, Sacha Gnjatic, Protul Shrikant, Lloyd J. Old, Immanuel Luescher, Takemasa Tsuji, Junko Matsuzaki

PDF file - 110K, Cell surface molecules expressed on SK-MEL-37.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3b02c024794774d7c2fa6900ada03da
https://doi.org/10.1158/2326-6066.22538548

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