Zobrazeno 1 - 10
of 2 092
pro vyhledávání: '"J, O'Keefe"'
Autor:
Daniela Nachmanson, Meghana Pagadala, Joseph Steward, Callie Cheung, Lauryn Keeler Bruce, Nicole Q. Lee, Thomas J. O’Keefe, Grace Y. Lin, Farnaz Hasteh, Gerald P. Morris, Hannah Carter, Olivier Harismendy
Publikováno v:
Journal of Translational Medicine, Vol 20, Iss 1, Pp 1-14 (2022)
Abstract Purpose The contribution of common genetic variants to pre-cancer progression is understudied due to long follow-up time, rarity of poor outcomes and lack of available germline DNA collection. Alternatively, DNA from diagnostic archival tiss
Externí odkaz:
https://doaj.org/article/29b803531c40467692cb9cd55653dcdb
Autor:
Julie Jin, MD, Zachery Hong, MD, MPHS, Lee Rhea, PhD, Douglas J. McDonald, MD, Regis J. O’Keefe, MD, PhD, Cara A. Cipriano, MD, MSc
Publikováno v:
JBJS Open Access, Vol 8, Iss 3 (2023)
Background:. The Toronto Extremity Salvage Score (TESS) and the National Institutes of Health Patient-Reported Outcomes Measurement Information System (PROMIS) are both utilized to measure patient-reported outcomes in adults with musculoskeletal onco
Externí odkaz:
https://doaj.org/article/c66b4405af664ee59dae77f1c46b0754
Publikováno v:
mBio, Vol 14, Iss 4 (2023)
ABSTRACT Prochlorococcus is an abundant photosynthetic bacterium in the open ocean, where nitrogen (N) often limits phytoplankton growth. In the low-light-adapted LLI clade of Prochlorococcus, nearly all cells can assimilate nitrite (NO2−), with a
Externí odkaz:
https://doaj.org/article/d9fc4e55b49c413391f5dbc26af96ced
Autor:
Amber L. Altrieth, Kevin J. O’Keefe, Victoria A. Gellatly, Joey R. Tavarez, Sage M. Feminella, Nicholas L. Moskwa, Carmalena V. Cordi, Judy C. Turrieta, Deirdre A. Nelson, Melinda Larsen
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Fibrosis results from excess extracellular matrix accumulation, which alters normal tissue architecture and impedes function. In the salivary gland, fibrosis can be induced by irradiation treatment for cancer therapy, Sjögren’s Disease, and other
Externí odkaz:
https://doaj.org/article/a0ff6601fb864efd93121addca352b5f
Autor:
Joseph G. Monir, MD, Kevin A. Hao, BS, Dilhan Abeyewardene, MD, Kevin J. O'Keefe, MD, Joseph J. King, MD, Thomas W. Wright, MD, Bradley S. Schoch, MD
Publikováno v:
JSES International, Vol 6, Iss 2, Pp 209-215 (2022)
Background: Rotator cuff tears and glenoid loosening remain the two most common causes for revision after anatomic total shoulder arthroplasty. Oversizing of the humeral head leads to increased contact force across the glenohumeral joint and is hypot
Externí odkaz:
https://doaj.org/article/d8738d34782f42808bb264bf986f1f00
Publikováno v:
Bone Research, Vol 9, Iss 1, Pp 1-14 (2021)
Abstract Glucose metabolism is fundamental for the functions of all tissues, including cartilage. Despite the emerging evidence related to glucose metabolism in the regulation of prenatal cartilage development, little is known about the role of gluco
Externí odkaz:
https://doaj.org/article/bb34989454114b979a69de69e5dd06c0
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract The Mediterranean diet, considered one of the healthiest in the world, is characterized in part by the major source of its fat, which is extra virgin olive oil (EVOO). Among the health benefits of consuming EVOOs is the presence of phenolic
Externí odkaz:
https://doaj.org/article/f38a15eec2b64fbbbdec4de344bb6aa4
Autor:
Carlos J. Sanchez, Andres Su, Camara Sharperson, Adam B. Prater, John J. O'Keefe, Matthew E. Zygmont, Raul G. Nogueira, Michael R. Frankel, Jason W. Allen, Ryan B. Peterson
Publikováno v:
Neuroscience Informatics, Vol 2, Iss 2, Pp 100058- (2022)
Background and purpose: Effective communication of radiologic findings is crucial in the acute evaluation of stroke. Conventional methods (CM) of communication can present challenges leading to delays in reporting, ultimately impacting patient outcom
Externí odkaz:
https://doaj.org/article/5171fa3cfa37476cba2a2109d77e8697
Autor:
Daniela Nachmanson, Joseph Steward, Huazhen Yao, Adam Officer, Eliza Jeong, Thomas J. O’Keefe, Farnaz Hasteh, Kristen Jepsen, Gillian L. Hirst, Laura J. Esserman, Alexander D. Borowsky, Olivier Harismendy
Publikováno v:
BMC Medical Genomics, Vol 13, Iss 1, Pp 1-15 (2020)
Abstract Background Systematic cancer screening has led to the increased detection of pre-malignant lesions (PMLs). The absence of reliable prognostic markers has led mostly to over treatment resulting in potentially unnecessary stress, or insufficie
Externí odkaz:
https://doaj.org/article/1f9e00e7637c4021a342f7e36b39379a
Autor:
Manoj Arra, Gaurav Swarnkar, Ke Ke, Jesse E. Otero, Jun Ying, Xin Duan, Takashi Maruyama, Muhammad Farooq Rai, Regis J. O’Keefe, Gabriel Mbalaviele, Jie Shen, Yousef Abu-Amer
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Chondrocytes have altered cellular metabolism in the context of osteoarthritis, but whether and how these changes are associated with inflammation is a controversial area. Here the authors show that inflammatory NF-κB signalling drives a glycolytic
Externí odkaz:
https://doaj.org/article/85329ba61e30432694e6760ca1cad04a