Zobrazeno 1 - 10
of 952
pro vyhledávání: '"J, Nikolic"'
Autor:
David A. Vesey, Abishek Iyer, Evan Owen, Danielle Kamato, David W. Johnson, Glenda C. Gobe, David P. Fairlie, David J. Nikolic-Paterson
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Key features of chronic kidney disease (CKD) include tubulointerstitial inflammation and fibrosis. Protease activated receptor-2 (PAR2), a G-protein coupled receptor (GPCR) expressed by the kidney proximal tubular cells, induces potent proinflammator
Externí odkaz:
https://doaj.org/article/acd3f424f03c4ce7a40cc0c7435e9fc3
Autor:
Natasha de Zoysa, Kotaro Haruhara, David J. Nikolic-Paterson, Peter G. Kerr, Jonathan Ling, Sarah E. Gazzard, Victor G. Puelles, John F. Bertram, Luise A. Cullen-McEwen
Publikováno v:
Frontiers in Medicine, Vol 11 (2024)
Corticosteroid therapy, often in combination with inhibition of the renin-angiotensin system, is first-line therapy for primary focal and segmental glomerulosclerosis (FSGS) with nephrotic-range proteinuria. However, the response to treatment is vari
Externí odkaz:
https://doaj.org/article/f1b0d3151ef243659d08ba006db972f9
Smad3 is essential for polarization of tumor-associated neutrophils in non-small cell lung carcinoma
Autor:
Jeff Yat-Fai Chung, Philip Chiu-Tsun Tang, Max Kam-Kwan Chan, Vivian Weiwen Xue, Xiao-Ru Huang, Calvin Sze-Hang Ng, Dongmei Zhang, Kam-Tong Leung, Chun-Kwok Wong, Tin-Lap Lee, Eric W-F Lam, David J. Nikolic-Paterson, Ka-Fai To, Hui-Yao Lan, Patrick Ming-Kuen Tang
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
TGF-β stimulated tumor-associated neutrophils (TANs) can exert pro-tumoral functions. Here the authors show that Smad3 activation in TANs is associated with an N2-like polarization state and poor outcome in patients with non-small cell lung carcinom
Externí odkaz:
https://doaj.org/article/ba3ca05e7ec94b9aa2d7bbddfdfd4bef
Autor:
Fan Yang, Elyce Ozols, Frank Y. Ma, Khai Gene Leong, Greg H. Tesch, Xiaoyun Jiang, David J. Nikolic-Paterson
Publikováno v:
Frontiers in Physiology, Vol 13 (2023)
Externí odkaz:
https://doaj.org/article/50392d401272425c9c2203ae36d2167b
Autor:
Lingyun Kong, Sofianos Andrikopoulos, Richard J MacIsaac, Laura K Mackay, David J Nikolic‐Paterson, Niloufar Torkamani, Neda Zafari, Evelyn C S Marin, Elif I Ekinci
Publikováno v:
Journal of Diabetes Investigation, Vol 13, Iss 2, Pp 213-226 (2022)
Abstract Diabetic kidney disease (DKD) is a highly prevalent complication of diabetes and the leading cause of end‐stage kidney disease. Inflammation is recognized as an important driver of progression of DKD. Activation of the immune response prom
Externí odkaz:
https://doaj.org/article/6acad139277844aaa238884180b0cf8c
Autor:
Clint D. Frye, Scott B. Donald, Catherine E. Reinhardt, Rebecca J. Nikolic, Lars F. Voss, Sara E. Harrison
Publikováno v:
Materials Research Letters, Vol 9, Iss 2, Pp 105-111 (2021)
The realization of vertical GaN devices requires deep plasma etching and is contingent on high mask selectivity. In this work, we show that SiO2 can be an effective mask material for deep etching GaN with GaN:SiO2 selectivities greater than 40—high
Externí odkaz:
https://doaj.org/article/d7f0af0ca49d482298413e2ee4f41945
Publikováno v:
Frontiers in Physiology, Vol 12 (2022)
Externí odkaz:
https://doaj.org/article/ac9b1e2d1fd843299fe49c2718e7d104
Publikováno v:
Radioengineering, Vol 28, Iss 4, Pp 729-739 (2019)
In this paper, we propose a novel model of dual-mode quantizer that combines the restricted and unrestricted forward adaptive piecewise linear scalar quantizers based on the first degree-spline functions, one of them being forward adaptive G.711 quan
Externí odkaz:
https://doaj.org/article/a3fb1c7e2dd042da87838a59865f7890
Autor:
Jinhua Li, Xinli Qu, Chengnong Guan, Ning Luo, Huiting Chen, Andy Li, Hongjie Zhuang, Jiayi Yang, Hui Diao, Shuhan Zeng, Qing Wang, Jinjin Fan, Mengjie Jiang, Xiaoyan Bai, Zhiming Ye, Xiaoyun Jiang, Wei Chen, David J. Nikolic-Paterson, Xueqing Yu
Publikováno v:
Kidney International. 103:886-902
Autor:
Fan Yang, Elyce Ozols, Frank Y. Ma, Khai Gene Leong, Greg H. Tesch, Xiaoyun Jiang, David J. Nikolic-Paterson
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
Aristolochic acid (AA) is a toxin that induces DNA damage in tubular epithelial cells of the kidney and is the cause of Balkan Nephropathy and Chinese Herb Nephropathy. In cultured tubular epithelial cells, AA induces a pro-fibrotic response via the
Externí odkaz:
https://doaj.org/article/7e134452bf7a4335884514e7c2558e8d