Zobrazeno 1 - 10
of 272
pro vyhledávání: '"J, McGaw"'
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 9, Pp 9639-9658 (2024)
Oxidative stress is a key factor that activates several transcription factors and mediators involved in the inflammatory pathways responsible for the pathogenesis of many chronic diseases. Targeting the expression of these mediators represents a prom
Externí odkaz:
https://doaj.org/article/32208cf5fb4b4d98b725e7ba7d3a444b
Autor:
Phanankosi Moyo, Michael Ofori, Olusola S. Bodede, Madelien Wooding, Ndivhuwo Kevin Khorommbi, Lyndy J. McGaw, Cynthia A. Danquah, Vinesh J. Maharaj
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-16 (2024)
Abstract The emergence of drug-resistant Mycobacterium tuberculosis strains is a threat to global health necessitating the discovery of novel chemotherapeutic agents. Natural products drug discovery, which previously led to the discovery of rifamycin
Externí odkaz:
https://doaj.org/article/bde2bd6ea9874e079e0bcf94e60c848a
Publikováno v:
Animals, Vol 14, Iss 21, p 3049 (2024)
The green shore crab (Carcinus maenas) is native to Western Europe but has spread around the globe and is described as one of the top 100 worst invasive species. On the east coast of North America, their northern-most limit is the island of Newfoundl
Externí odkaz:
https://doaj.org/article/a03533270bdc4c43b16176a69f0deb76
Publikováno v:
Journal of Applied Animal Research, Vol 50, Iss 1, Pp 656-665 (2022)
This study determines the phytochemical contents of selected medicinal plant extracts quantitatively using spectrophotometry and to evaluate their safety on mammalian cells in vitro using tetrazolium-based colorimetric cytotoxicity assay. Twenty-two
Externí odkaz:
https://doaj.org/article/f368c142f8074107919bf59bc7010a5e
Autor:
Emmanuel Mfotie Njoya, Brigitte Ndemangou, Jude Akinyelu, Aristide M. Munvera, Chika. I. Chukwuma, Pierre Mkounga, Samson S. Mashele, Tshepiso J. Makhafola, Lyndy J. McGaw
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Background:Sarcocephalus pobeguinii (Hua ex Pobég) is used in folk medicine to treat oxidative-stress related diseases, thereby warranting the investigation of its anticancer and anti-inflammatory properties. In our previous study, the leaf extract
Externí odkaz:
https://doaj.org/article/6a82dc807d2c4841a2002f3ab33b12f5
Autor:
Michael Heinrich, Banaz Jalil, Mona Abdel-Tawab, Javier Echeverria, Žarko Kulić, Lyndy J. McGaw, John M. Pezzuto, Olivier Potterat, Jia-Bo Wang
Publikováno v:
British Journal of Pharmacy, Vol 7, Iss 2 (2022)
Every year, the number of studies that evaluate the pharmacological effects, (clinical) efficacy or the toxicity of medicinal plant extracts is constantly increasing, but the reporting quality remains unsatisfactory. One of the main reasons is that t
Externí odkaz:
https://doaj.org/article/22caa330eb6c4c6d8a3146d55628686c
Autor:
Tumelo L. Molokoane, Douglas Kemboi, Xavier Siwe-Noundou, Ibukun M. Famuyide, Lyndy J. McGaw, Vuyelwa J. Tembu
Publikováno v:
Plants, Vol 12, Iss 19, p 3369 (2023)
Secondary metabolites were isolated using chromatographic techniques after being extracted sequentially from the roots of Artemisia afra using organic solvents such as ethanol, ethyl acetate, dichloromethane, and n-hexane. The isolated compounds were
Externí odkaz:
https://doaj.org/article/18d558e51cab499890ab52e3ae94536a
Autor:
Sibonokuhle F. Ncube, Lyndy J. McGaw, Emmanuel Mfotie Njoya, Hilton G. T. Ndagurwa, Peter J. Mundy, Samson Sibanda
Publikováno v:
BMC Complementary Medicine and Therapies, Vol 21, Iss 1, Pp 1-9 (2021)
Abstract Background This study evaluated the in vitro antioxidant activity and comparison of anti-inflammatory and cytotoxic activity of Harpagopytum zeyheri with diclofenac. Methods In vitro assays were conducted using water, ethanol, and ethyl acet
Externí odkaz:
https://doaj.org/article/4de70128dd724101999334005b6dfcf5
Autor:
Michael Heinrich, Banaz Jalil, Mona Abdel-Tawab, Javier Echeverria, Žarko Kulić, Lyndy J. McGaw, John M. Pezzuto, Olivier Potterat, Jia-Bo Wang
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Background: Research on medicinal plants and extracts derived from them differs from studies performed with single compounds. Extracts obtained from plants, algae, fungi, lichens or animals pose some unique challenges: they are multicomponent mixture
Externí odkaz:
https://doaj.org/article/57ba3b7f7e4d43548f8e4de65752ab4c
Publikováno v:
Frontiers in Veterinary Science, Vol 9 (2022)
Externí odkaz:
https://doaj.org/article/bbef7dda8cdb42bb819643aaaa6df785