Zobrazeno 1 - 10
of 409
pro vyhledávání: '"J, Mandl"'
Autor:
Benjamin J. Mandl, Ben Y. Reis
Publikováno v:
npj Digital Medicine, Vol 5, Iss 1, Pp 1-11 (2022)
Abstract In times of crisis, communication by leaders is essential for mobilizing an effective public response. During the COVID-19 pandemic, compliance with public health guidelines has been critical for the prevention of infections and deaths. We a
Externí odkaz:
https://doaj.org/article/1ef7a01a02574a39beb831b3b6b543dc
Akademický článek
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Autor:
Alain Delcayre, Reiner Laus, Ulrike Dirmeier, Kay Brinkmann, Peter L. Schoonmaker, John R. Lombardo, Lisa Do, Katie Dalpozzo, James M. Nachtwey, Stefanie J. Mandl, Ryan B. Rountree
Supplementary Figure 2 from Exosome Targeting of Tumor Antigens Expressed by Cancer Vaccines Can Improve Antigen Immunogenicity and Therapeutic Efficacy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a65f5aab699a7eeefc93c7c2ca081acc
https://doi.org/10.1158/0008-5472.22387740.v1
https://doi.org/10.1158/0008-5472.22387740.v1
Autor:
Alain Delcayre, Reiner Laus, Ulrike Dirmeier, Kay Brinkmann, Peter L. Schoonmaker, John R. Lombardo, Lisa Do, Katie Dalpozzo, James M. Nachtwey, Stefanie J. Mandl, Ryan B. Rountree
Supplementary Figure 1 from Exosome Targeting of Tumor Antigens Expressed by Cancer Vaccines Can Improve Antigen Immunogenicity and Therapeutic Efficacy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43aef7729099cc34886d79dfedf9a8ff
https://doi.org/10.1158/0008-5472.22387743.v1
https://doi.org/10.1158/0008-5472.22387743.v1
Autor:
Susan P. Foy, Kyle Jacoby, Daniela A. Bota, Theresa Hunter, Zheng Pan, Eric Stawiski, Yan Ma, William Lu, Songming Peng, Clifford L. Wang, Benjamin Yuen, Olivier Dalmas, Katharine Heeringa, Barbara Sennino, Andy Conroy, Michael T. Bethune, Ines Mende, William White, Monica Kukreja, Swetha Gunturu, Emily Humphrey, Adeel Hussaini, Duo An, Adam J. Litterman, Boi Bryant Quach, Alphonsus H. C. Ng, Yue Lu, Chad Smith, Katie M. Campbell, Daniel Anaya, Lindsey Skrdlant, Eva Yi-Hsuan Huang, Ventura Mendoza, Jyoti Mathur, Luke Dengler, Bhamini Purandare, Robert Moot, Michael C. Yi, Roel Funke, Alison Sibley, Todd Stallings-Schmitt, David Y. Oh, Bartosz Chmielowski, Mehrdad Abedi, Yuan Yuan, Jeffrey A. Sosman, Sylvia M. Lee, Adam J. Schoenfeld, David Baltimore, James R. Heath, Alex Franzusoff, Antoni Ribas, Arati V. Rao, Stefanie J. Mandl
Publikováno v:
Nature, vol 615, iss 7953
T cell receptors (TCRs) enable T cells to specifically recognize mutations in cancer cells1–3. Here we developed a clinical-grade approach based on CRISPR–Cas9 non-viral precision genome-editing to simultaneously knockout the two endogenous TCR g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd691b6fa2cf73c26cc536f7201c6b0c
https://escholarship.org/uc/item/2g96s8v7
https://escholarship.org/uc/item/2g96s8v7
Publikováno v:
Cancer Research. 83:3125-3125
Background: Adoptive T-cell therapies would benefit from accurate computational prediction of T cell receptor (TCR) specificity to its target antigen. Despite the diversity of complementarity determining region (CDR) among T cells, many sequence feat
Autor:
Susan P Foy, Barbara Sennino, Tracy dela Cruz, Joseph J Cote, Evan J Gordon, Felicia Kemp, Veronica Xavier, Alex Franzusoff, Ryan B Rountree, Stefanie J Mandl
Publikováno v:
PLoS ONE, Vol 11, Iss 2, p e0150084 (2016)
Poxvirus-based active immunotherapies mediate anti-tumor efficacy by triggering broad and durable Th1 dominated T cell responses against the tumor. While monotherapy significantly delays tumor growth, it often does not lead to complete tumor regressi
Externí odkaz:
https://doaj.org/article/cc7e12682bbf4a1697d92a736c69d78a
Publikováno v:
Viszeralmedizin 2021 Gemeinsame Jahrestagung Deutsche Gesellschaft für Gastroenterologie, Verdauungs- und Stoffwechselkrankheiten (DGVS), Sektion Endoskopie der DGVS, Deutsche Gesellschaft für Allgemein und Viszeralchirurgie (DGAV).
Autor:
R. Sting, A.K. Schwalm, C. Metzger-Boddien, Anna Obiegala, Martin Pfeffer, G. Seemann, J. Mandl
Publikováno v:
Journal of Dairy Science. 102:11260-11267
Bovine paratuberculosis (Johne's disease) is a bacterial, chronic, and wasting intestinal disease caused by Mycobacterium avium ssp. paratuberculosis (MAP). Johne's disease causes severe losses in dairy farm productivity and is also suspected to be a
Autor:
Charles W. Tran, Kayla Lee, Bhamini Purandare, James Byers, Michael M. Dubreuil, William Lu, Michal Mass, Kyle Jacoby, Stefanie J. Mandl, Barbara Sennino
Publikováno v:
Cancer Research. 82:2829-2829
Personalized autologous TCR-T cell therapies targeting neoepitopes (neoE) derived from tumor-specific mutations are a compelling approach for the treatment of patients with solid tumors. Using the ultra-sensitive imPACT Isolation Technology®, antige