Zobrazeno 1 - 10
of 87
pro vyhledávání: '"J, Macías Sánchez"'
Autor:
Felipe Escobar-Montaño, Antonio J. Macías-Sánchez, José M. Botubol-Ares, Rosa Durán-Patrón, Rosario Hernández-Galán
Publikováno v:
Plants, Vol 13, Iss 6, p 842 (2024)
Premyrsinane-type diterpenoids have been considered to originate from the cyclization of a suitable 5,6- or 6,17-epoxylathyrane precursor. Their biological activities have not been sufficiently explored to date, so the development of synthetic or mic
Externí odkaz:
https://doaj.org/article/51343340fa494b35b077b9f9ca3b48c9
Autor:
Felipe Escobar-Montaño, Victoria E. González-Rodríguez, Antonio J. Macías-Sánchez, José M. Botubol-Ares, Rosa Durán-Patrón, Rosario Hernández-Galán
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 4, p 2289 (2024)
Lathyrane-type diterpenes have a wide range of biological activities. Among them, euphoboetirane A (1) exerts neurogenesis-promoting activity. In order to increase the structural diversity of this type of lathyrane and explore its potential use in ne
Externí odkaz:
https://doaj.org/article/e0d60c06393a4a13a0189823d6056145
Publikováno v:
Plants, Vol 12, Iss 22, p 3846 (2023)
Diterpenes from the Euphorbia genus are known for their ability to regulate the protein kinase C (PKC) family, which mediates their ability to promote the proliferation of neural precursor cells (NPCs) or neuroblast differentiation into neurons. In t
Externí odkaz:
https://doaj.org/article/3582d4aa389e4eec9092d92f97921556
Autor:
Adriana de Almeida Pinto Bracarense, Jociani Ascari, Giovanni Gontijo de Souza, Thays Silva Oliveira, Antonio Ruano-González, Ana A. Pinto, Maria Amélia Diamantino Boaventura, Jacqueline Aparecida Takahashi, Isidro G. Collado, Rosa Durán-Patrón, Antonio J. Macías-Sánchez
Publikováno v:
Journal of Fungi, Vol 7, Iss 12, p 1079 (2021)
Clovane and isocaryolane derivatives have been proven to show several levels of activity against the phytopathogenic fungus Botrytis cinerea. Both classes of sesquiterpenes are reminiscent of biosynthetic intermediates of botrydial, a virulence facto
Externí odkaz:
https://doaj.org/article/b5963c10522e4054983e92ac2521d7fd
Autor:
Ana A. Pinto, Javier E. Barúa, Marilia O. Almeida, Muriel Viaud, David Zorrilla, Isidro G. Collado, Antonio J. Macías-Sánchez, Rosa Durán-Patrón
Publikováno v:
Bioorganic chemistry. 127
Chemical epigenetic manipulation of Botrytis cinerea strain B05.10 with the histone deacetylase inhibitor SAHA led to the isolation of a new cryptic metabolite, botrycinereic acid (22a). This compound was also overproduced by inactivating the stc2 ge
Autor:
Abdellah Ezzanad, Ricardo Gómez-Oliva, Felipe Escobar-Montaño, Mónica Díez-Salguero, Noelia Geribaldi-Doldan, Samuel Dominguez-Garcia, José Manuel Botubol-Ares, Carolina de los Reyes, Rosa Durán-Patrón, Pedro Nunez-Abades, Antonio J. Macías-Sánchez, Carmen Castro, Rosario Hernández-Galán
Publikováno v:
Journal of Medicinal Chemistry. 65:10707-10708
Autor:
Ivonne, Suárez, Cristina, Pinedo, Josefina, Aleu, Rosa, Durán-Patrón, Antonio J, Macías-Sánchez, Rosario, Hernández-Galán, Isidro G, Collado
Publikováno v:
Phytochemistry. 193
Botrytis cinerea has high potential for the production of specialized metabolites. The recent resequencing of the genome of the B05.10 strain using PacBio technology and the resulting update of the Ensembl Fungi (2017) database in the genome sequence
Autor:
Antonio J. Macías-Sánchez, Maribel Murillo-Carretero, Carmen Castro, Noelia Geribaldi-Doldán, Eugenia Flores-Giubi, Rosario Hernández-Galán, Rosa Durán-Patrón
Publikováno v:
Journal of Natural Products. 82:2517-2528
Lathyrane-type diterpenes previously have been proven to promote proliferation of neural precursor cells (NPCs) by targeting and activating one or more protein kinase C (PKC) isozymes. Aiming to find new drug candidates with a lathyrane skeleton to m
Publikováno v:
ARKIVOC, Vol 2002, Iss 8, Pp 46-56 (2002)
Externí odkaz:
https://doaj.org/article/64031652531a4e0f9d721aecac78e04f
Autor:
Raphael Conti, Gesiane da Silva Lima, Ana Ligia Leandrini de Oliveira, Javier Barua, Mônica Tallarico Pupo, Josefina Aleu, James R. Hanson, Rosa Durán-Patrón, Cristina Pinedo, Antonio J. Macías-Sánchez, Rosario Hernández-Galán, Isidro G. Collado, Javier Moraga, Ivonne Suárez
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
A thorough study of the fermentation broth of three strains of Botrytis cinerea which were grown on a modified Czapek-Dox medium supplemented with 5 ppm copper sulphate, yielded five undescribed metabolites. These metabolites possessed a sesquiterpen