Zobrazeno 1 - 10
of 224
pro vyhledávání: '"J, Leibovici"'
Autor:
S, Kay, M, Michowitz, N, Donin, D, Katzenelson, A, Siegal, J, Sinai, J, Ravia, A, Pinchassov, J, Leibovici
Publikováno v:
Apoptosis : an international journal on programmed cell death. 4(6)
Resistance to apoptosis may be related to tumor progression, due to the implications it might have on both tumor mass and genetic instability. We compared the tendency to spontaneous apoptosis and the proliferative capacity of metastatic growths of s
Autor:
T, Kaptzan, E, Skutelsky, M, Michowitz, A, Siegal, O, Itzhaki, S, Hoenig, J, Hiss, S, Kay, J, Leibovici
Publikováno v:
Advances in experimental medicine and biology. 479
Resistance to immune reactions, innate or acquired, may be one of the mechanisms responsible for the progression of tumors. We have, indeed shown higher numbers of macrophages surrounding low- as compared to high-malignancy cells. In the present stud
Autor:
O, Itzhaki, E, Skutelsky, T, Kaptzan, A, Siegal, M, Michowitz, J, Sinai, M, Huszar, S, Nafar, J, Leibovici
Publikováno v:
Advances in experimental medicine and biology. 479
While a direct relation between aging and tumorigenesis is well established, a slower tumor progression rate was reported in old as compared to young cancer patients. The mechanisms responsible for the less aggressive behavior of tumors in the aged,
Autor:
A N, Staroselsky, T, Mahlin, N, Savion, O, Klein, J, Nordenberg, N, Donin, M, Michowitz, J, Leibovici
Publikováno v:
Journal of experimental therapeuticsoncology. 1(4)
The question of whether metastatic potential and drug resistance are related phenotypes was addressed by comparing the biological behavior of the parental B16 melanoma and a multidrug resistant variant derived from it, the B16/Col/R. A more pronounce
Publikováno v:
Invasionmetastasis. 15(5-6)
Multiple structural and functional cell properties are responsible for the complex phenotype of the metastatic cell. Cells derived from AKR lymphoma malignancy variants were compared with regard to several cellular functions relevant to the metastati
Publikováno v:
Cellular and molecular biology (Noisy-le-Grand, France). 40(4)
Tumor progression (TP) is often accompanied by evolution of drug resistant clones. Decreased intracellular accumulation of cytotoxic agents is probably the major mechanism of drug resistance. In the present study, we tried to examine the possibility
Enhancement of cytotoxic agent accumulation by Doppler flow sonication of human ovarian cancer cells
Publikováno v:
European journal of gynaecological oncology. 15(4)
The intracellular accumulation of adriamycin (ADR) by Doppler flow sonication was investigated in a human ovarian carcinoma line. Cytofluorometry was performed on cells treated by ADR (0.5, 1 and 2 micrograms/mL) alone, or in conjunction with Doppler
Publikováno v:
Cellular and molecular biology (Noisy-le-Grand, France). 39(8)
Lectin-histochemical studies were performed on macrophages activated by Nocardia opaca water soluble molecules (NWSM) and elicited by phosphate buffered saline (PBS) as control to demonstrate the pattern of carbohydrate residues. Ten different biotin
Publikováno v:
International journal of experimental pathology. 73(3)
The comprehension of tumour progression has advanced due to the use of various models, the most rewarding being probably the study of malignancy variants derived from the same tumour. In the present study the biological behaviours of three AKR lympho
Publikováno v:
In vivo (Athens, Greece). 5(4)
Several immunomodulatory fractions derived from Nocardia have been found to inhibit the growth of several experimental tumors, including Lewis lung carcinoma (3LL). An involvement of both macrophages and lymphocytes in the antitumoral effect of Nocar