Zobrazeno 1 - 10
of 132
pro vyhledávání: '"J, Laudanski"'
Publikováno v:
European Respiratory Journal. 8:291-294
We wanted to investigate the diagnostic and prognostic significance of serum CYFRA 21-1, especially in predicting the risk of recurrence in patients with operable squamous cell lung cancer. Serum levels of CYFRA 21-1 were measured using an immunoradi
Autor:
R M, Mroz, K, Kordecki, M D, Kozlowski, A, Baniukiewicz, A, Lewszuk, Z, Bondyra, J, Laudanski, A, Dabrowski, E, Chyczewska
Publikováno v:
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society. 59
We investigate retrospectively the efficacy of self-expandable metallic stents (SEMS) for severe respiratory distress (SRD) in patients with central airway obstruction (CAO). Thirty three patients with CAO were treated with SEMS using fiberoptic bron
Autor:
A, Holownia, R M, Mroz, M, Kozlowski, E, Chyczewska, J, Laudanski, L, Chyczewski, J J, Braszko
Publikováno v:
Neoplasma. 50(4)
p53 protein is a critical regulator of the cell cycle and apoptosis and its levels and functions change in response to many stimuli. To assess whether the cytotoxic drugs induce DNA changes, affect phosphorylation and stability of p53 protein, we det
Publikováno v:
Folia histochemica et cytobiologica. 39
We investigated the clinical significance of p16 abnormalities (mutations by sequencing and hypermethylation by methylation-specific PCR) in 52 radically resected stage I-II non-small cell lung cancers (NSCLCs). P16 abnormalities were detected in 20
G1 phase of the cell cycle control and lung cancer: biological and clinical implications. Minireview
Publikováno v:
Neoplasma. 48(3)
Neoplastic diseases, including lung cancer are characterized by an uncoordinated cell growth. Cellular proliferation follows an orderly progression through the cell cycle, which is governed by protein complexes composed of cyclins and cyclin-dependen
Publikováno v:
Folia histochemica et cytobiologica. 39(2)
We assessed the status of P53 in 32 surgically treated non-small cell lung cancers (NSCLC) by using yeast functional assay. For functional assay, total RNA extracted from fresh-frozen specimens was reverse transcribed and P53 cDNAs were PCR-amplified
Publikováno v:
Folia histochemica et cytobiologica. 39(2)
DNA sequencing is the gold-standard method, but it is not feasible on a routine clinical basis. Immunohistochemistry is the most widely used method for assessing P53 alterations in human cancers. It can be performed during routine analysis, but some
Autor:
J, Laudanski, L, Chyczewski, W E, Niklińska, M, Kretowska, M, Furman, B, Sawicki, J, Nikliński
Publikováno v:
Neoplasma. 46(1)
Molecular genetic studies have revealed mutations in a number of oncogenes and tumor suppressor genes in lung cancer. The bcl-2 gene product (bcl-2 protein) is implicated in oncogenesis by its ability to prolong cell death through the inhibition of a
Autor:
M Furman, M Rapellino, E Chyczewska, J Niklinski, Tomasz Burzykowski, Lech Chyczewski, J. Laudanski
Publikováno v:
British Journal of Cancer
Scopus-Elsevier
Scopus-Elsevier
The CYFRA 21-1 assay is a test that has been developed recently for detection of a cytokeratin 19 fragment in serum. A diagnostic role for CYFRA 21-1 has already been proposed. The question of whether this marker is prognostically significant is impo
Publikováno v:
Neoplasma. 40(5)
To evaluate the diagnostic usefulness of simultaneous determinations of carcinoembryonic antigen (CEA), neuron specific enolase (NSE), chorionic gonadotrophin (HCG) and carbohydrate antigenic determinant 19-9 (CA 19-9), we studied 48 patients with sm