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Akademický článek

Evaluation of the neutralizing capacity of Androctonus crassicauda (Olivier, 1807) antivenom against Leiurus quinquestriatus (Ehrenberg, 1928) venom (Scorpiones: Buthidae)

Autor: O Ozkan, S Adiguzel, B Inceoglu, J Lango, M Ertek, BD Hammock

Publikováno v: Journal of Venomous Animals and Toxins including Tropical Diseases, Vol 14, Iss 3, Pp 481-496 (2008)

The two most venomous species of the family Buthidae, Leiurus quinquestriatus and Androctonus crassicauda, are found in Africa and in the Middle East. Potency and paraspecific activities of A. crassicauda antivenom (RSHC anti-Ac) were tested against

Externí odkaz: https://doaj.org/article/d572eea8ecf94f039723d70835c6fb76

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Survivin expression and impact on head and neck cancer outcomes

Autor: Barbara Burtness, Dong-Hua Yang, Ranee Mehra, Fang Zhu, Miriam J. Lango, John A. Ridge, David J. Sher, Saad A. Khan, Cara Dubyk, Michael Burke

Publikováno v: Oral oncology. 112

Introduction Survivin is an inhibitor of apoptosis that is proposed as a target for anti-cancer therapy because of its high expression in cancer cells. It has potential as a prognostic and predictive biomarker of response to radiation and systemic th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d68ff0cd269f9abdf6ea8be33a2ec9cb
https://pubmed.ncbi.nlm.nih.gov/33221541

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Domestic cats convert [2H8]-β-carotene to [2H4]-retinol following a single oral dose

Autor: A. S. Green, G. Tang, J. Lango, Andrea J. Fascetti, Kirk C. Klasing

Publikováno v: Journal of Animal Physiology and Animal Nutrition. 96:681-692

Many animals convert β-carotene to retinol to meet their vitamin A (VA) requirement. However, this pathway is inefficient in many carnivores. This study quantified the plasma response to a single oral dose of [(2) H(8)]-β-carotene in adult domestic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::234dedee4c4365faed42a677224e2647
https://doi.org/10.1111/j.1439-0396.2011.01196.x

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Pharmacokinetics and in vivo potency of soluble epoxide hydrolase inhibitors in cynomolgus monkeys

Autor: A, Ulu, Se, Appt, C, Morisseau, S H, Hwang, P D, Jones, T E, Rose, H, Dong, J, Lango, J, Yang, H J, Tsai, C, Miyabe, C, Fortenbach, M R, Adams, B D, Hammock

Publikováno v: British journal of pharmacology. 165(5)

Soluble epoxide hydrolase inhibitors (sEHIs) possess anti-inflammatory, antiatherosclerotic, antihypertensive and analgesic properties. The pharmacokinetics (PK) and pharmacodynamics in terms of inhibitory potency of sEHIs were assessed in non-human

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::777fe3a313120118b2429041cecc2019
https://pubmed.ncbi.nlm.nih.gov/21880036

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Isolation and characterization of a novel type of neurotoxic peptide from the venom of the South African scorpion Parabuthus transvaalicus (Buthidae)

Autor: B, Inceoglu, J, Lango, J, Wu, P, Hawkins, J, Southern, B D, Hammock

Publikováno v: European journal of biochemistry. 268(20)

The venom of the South African scorpion Parabuthus transvaalicus was characterized using a combination of mass spectrometry and RP-HPLC separation and bioassays. The crude venom was initially separated into 10 fractions. A novel, moderately toxic but

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5a2c3cc0b14041d18869d4412b6d7db3
https://pubmed.ncbi.nlm.nih.gov/11606203

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