Zobrazeno 1 - 10
of 467
pro vyhledávání: '"J, Landsberg"'
Autor:
Jason N. Busby, Sarah Trevelyan, Cassandra L. Pegg, Edward D. Kerr, Benjamin L. Schulz, Irene Chassagnon, Michael J. Landsberg, Mitchell K. Weston, Mark R. H. Hurst, J. Shaun Lott
Publikováno v:
IUCrJ, Vol 11, Iss 3, Pp 299-308 (2024)
Bacterial ABC toxin complexes (Tcs) comprise three core proteins: TcA, TcB and TcC. The TcA protein forms a pentameric assembly that attaches to the surface of target cells and penetrates the cell membrane. The TcB and TcC proteins assemble as a hete
Externí odkaz:
https://doaj.org/article/dcb2f060e5bd4484b41d76245489dbbd
Autor:
Ariel Isaacs, Yu Shang Low, Kyle L. Macauslane, Joy Seitanidou, Cassandra L. Pegg, Stacey T. M. Cheung, Benjamin Liang, Connor A. P. Scott, Michael J. Landsberg, Benjamin L. Schulz, Keith J. Chappell, Naphak Modhiran, Daniel Watterson
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-10 (2023)
Abstract In August 2022, a novel henipavirus (HNV) named Langya virus (LayV) was isolated from patients with severe pneumonic disease in China. This virus is closely related to Mòjiāng virus (MojV), and both are divergent from the bat-borne HNV mem
Externí odkaz:
https://doaj.org/article/fbdd4a3ec69d474eae19a4b3f509ca86
Autor:
Harry W. Rathbone, Katharine A. Michie, Michael J. Landsberg, Beverley R. Green, Paul M. G. Curmi
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
Cryptophytes acquired plastids from red algae but replaced the light-harvesting phycobilisome with a unique cryptophyte antenna. Here via analysis of phycobilisome cryo-EM structures, Rathbone et al. propose that the α subunit of the cryptophyte ant
Externí odkaz:
https://doaj.org/article/ffa3d86fb4c948eb907e6cfce538ee28
Autor:
Melissa D. Ilsley, Stephen Huang, Graham W. Magor, Michael J. Landsberg, Kevin R. Gillinder, Andrew C. Perkins
Publikováno v:
BMC Genomics, Vol 20, Iss 1, Pp 1-12 (2019)
Abstract Background Mutations in the transcription factor, KLF1, are common within certain populations of the world. Heterozygous missense mutations in KLF1 mostly lead to benign phenotypes, but a heterozygous mutation in a DNA-binding residue (E325K
Externí odkaz:
https://doaj.org/article/d7f2e1bf360e43048a27dc210a3c1440
Autor:
Sarah J Piper, Lou Brillault, Rosalba Rothnagel, Tristan I Croll, Joseph K Box, Irene Chassagnon, Sebastian Scherer, Kenneth N Goldie, Sandra A Jones, Femke Schepers, Lauren Hartley-Tassell, Thomas Ve, Jason N Busby, Julie E Dalziel, J Shaun Lott, Ben Hankamer, Henning Stahlberg, Mark R H Hurst, Michael J Landsberg
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
YenTcA is the pore-forming and membrane binding subunit of the ABC toxin YenTc, which is produced by the insect pathogen Yersinia entomophaga. Here authors present cryo-EM structures of YenTcA purified from the native source which implicate associate
Externí odkaz:
https://doaj.org/article/22ed524a9e8c453c8589dc7718c89ba1
Autor:
Jason K.K. Low, Ana P.G. Silva, Mehdi Sharifi Tabar, Mario Torrado, Sarah R. Webb, Benjamin L. Parker, Maryam Sana, Callum Smits, Jason W. Schmidberger, Lou Brillault, Matthew J. Jackman, David C. Williams, Jr., Gerd A. Blobel, Sandra B. Hake, Nicholas E. Shepherd, Michael J. Landsberg, Joel P. Mackay
Publikováno v:
Cell Reports, Vol 33, Iss 9, Pp 108450- (2020)
Summary: The nucleosome remodeling and deacetylase (NuRD) complex is essential for metazoan development but has been refractory to biochemical analysis. We present an integrated analysis of the native mammalian NuRD complex, combining quantitative ma
Externí odkaz:
https://doaj.org/article/67462e4b5dec48dc92db0b2bce9d1594
Autor:
Christopher L. D. McMillan, Armira Azuar, Jovin J. Y. Choo, Naphak Modhiran, Alberto A. Amarilla, Ariel Isaacs, Kate E. Honeyman, Stacey T. M. Cheung, Benjamin Liang, Maria J. Wurm, Paco Pino, Joeri Kint, Germain J. P. Fernando, Michael J. Landsberg, Alexander A. Khromykh, Jody Hobson-Peters, Daniel Watterson, Paul R. Young, David A. Muller
Publikováno v:
Vaccines, Vol 10, Iss 4, p 578 (2022)
The ongoing coronavirus disease 2019 (COVID-19) pandemic continues to disrupt essential health services in 90 percent of countries today. The spike (S) protein found on the surface of the causative agent, the SARS-CoV-2 virus, has been the prime targ
Externí odkaz:
https://doaj.org/article/047b2bd3483b4cd9b6da0a66f2543ada
Publikováno v:
Biochemical Society Transactions.
ABC toxins are pore-forming toxins characterised by the presence of three distinct components assembled into a hetero-oligomeric toxin complex ranging in size from 1.5–2.5 MDa. Most ABC toxins studied to date appear to be insecticidal toxins, altho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::525a98131c12b3a193bab873d8d0d43b
https://doi.org/10.1042/bst20221409
https://doi.org/10.1042/bst20221409
Akademický článek
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Autor:
Joerg Wenzel, Christine Braegelmann, Dennis Niebel, Michael Hölzel, S Steinbuch, S Ferring-Schmitt, Thomas Bieber, Tanja Fetter, J Landsberg, Nicole Glodde, M Effern
Publikováno v:
Journal of the European Academy of Dermatology and Venereology. 36:144-153
Background Epigallocatechin-3-gallate (EGCG) has been proven effective in treating viral warts. Since anticarcinogenic as well as anti-inflammatory properties are ascribed to the substance, its use has been evaluated in the context of different derma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::934560b526afe694b88ef2229c0004a9
https://doi.org/10.1111/jdv.17710
https://doi.org/10.1111/jdv.17710