Zobrazeno 1 - 10
of 122
pro vyhledávání: '"J, Kusenda"'
Autor:
J Kusenda, A Kovarikova
Publikováno v:
Neoplasma. 63:651-658
Multiple myeloma (MM) is an incurable heterogeneous hematological malignancy in which relapse is characterized by re-growth of residual tumor and immune suppression with a complex biology that affects many aspects of the disease and its response to t
Publikováno v:
Neoplasma. 61:119-127
In this review, we discuss methodological principles and clinical applications of minimal residual disease (MRD) assays based on multiparameter flow cytometry (MFC). The introduction of methods for MRD detection has revolutionized monitoring of treat
Autor:
J, Kusenda
Publikováno v:
Neoplasma. 55(5)
Fluorescence intensity (FI) is the basis for classifying phenotypes by fluorescence-label flow cytometry. FI is of a relative value, but with calibration it can be expressed in stoichiometric units called molecules of equivalent soluble fluorochrome
Publikováno v:
Neoplasma. 52(6)
Bone marrow hematogones (benign B-lymphocyte precursors) may cause diagnostic problems due to their morphologic and immunophenotypic similarities with neoplastic lymphoblasts. Hematogone populations in presented study containing 358 bone marrow speci
Publikováno v:
Neoplasma. 52(3)
The purpose of this study was to assess the possible relationship between the cytochemical enzyme profile and immunophenotypic characteristics of distinct acute myeloid leukemia (AML) subtypes in discrete stages of leukemic cells maturation. As the p
Autor:
J, Kusenda, O, Babusíková
Publikováno v:
Neoplasma. 51(2)
Presented study analyzed the immunophenotypic characteristics and antigen density of peripheral blood (PB) and bone marrow (BM) cells of 23 patients with B-chronic lymphocytic leukemia (B-CLL) and 10 control subjects using flow cytometry. The patient
Publikováno v:
Neoplasma. 50(6)
The aim of this study was to assess the possible relationship between the silver stained nucleolar organizer regions (AgNOR) and immunocytochemically detected p53 and bcl-2 proteins in ALL, AML, B-CLL and CML patients (adults and children) at the ini
Autor:
E, Koníková, J, Kusenda
Publikováno v:
Neoplasma. 50(1)
In order to define the possible role of the MDM2 gene in the pathogenesis of human leukemia, the expression of MDM2 protein was examined in samples of fixed-permeabilized peripheral blood (PB) or bone marrow (BM) cells of leukemic patients by using f
Publikováno v:
Neoplasma. 49(6)
B-cell chronic lymphocytic leukemia (B-CLL) is a disease with variable course and prognosis. It may be important to predict the possible risk of disease progression in individual patients. We have investigated by immunocytochemistry the bcl-2 and p53
Publikováno v:
Neoplasma. 48(6)
We have analyzed by immunocytochemistry the p53 and Bcl-2 proteins expression in 49 patients with B-ALL, T-ALL and AML at the time of initial diagnosis. The diagnosis was based on morphologic and cytochemical criteria and on immunophenotyping. To dem