Zobrazeno 1 - 10
of 24
pro vyhledávání: '"J, Kupko"'
Autor:
Sebenzile Myeni, Robert Child, Tony W Ng, John J Kupko, Tara D Wehrly, Stephen F Porcella, Leigh A Knodler, Jean Celli
Publikováno v:
PLoS Pathogens, Vol 9, Iss 8, p e1003556 (2013)
The intracellular pathogenic bacterium Brucella generates a replicative vacuole (rBCV) derived from the endoplasmic reticulum via subversion of the host cell secretory pathway. rBCV biogenesis requires the expression of the Type IV secretion system (
Externí odkaz:
https://doaj.org/article/34971f7e393b47f89c27fac22e30ea47
Autor:
Vinod Nair, Jean Celli, Deborah D. Crane, John J. Kupko, Dan E. Sturdevant, Tara D. Wehrly, Craig Martens, Dedeke Brouwer, Elizabeth R. Fischer, Kimmo Virtaneva, Audrey Chong, Luke Wicke, Jessica A. Edwards, Robert Child, Alissa J. Curda, Stephen F. Porcella, Catharine M. Bosio
Publikováno v:
Cellular Microbiology. 11:1128-1150
Summary The highly infectious bacterium Francisella tularensis is a facultative intracellular pathogen, whose virulence requires proliferation inside host cells, including macrophages. Here we have performed a global transcriptional profiling of the
Autor:
Dan E. Sturdevant, John J. Kupko, Kent D. Barbian, Adrian M. Zelazny, David W. Dorward, Amenah Babar, Steven M. Holland, David E. Greenberg, Kimmo Virtaneva, Stephen F. Porcella
Publikováno v:
Journal of Bacteriology. 189:8727-8736
Chronic granulomatous disease (CGD) is an inherited immune deficiency characterized by increased susceptibility to infection with Staphylococcus , certain gram-negative bacteria, and fungi. Granulibacter bethesdensis , a newly described genus and spe
Autor:
Jonathan G. Krum, John J. Kupko, Abdallah F. Elias, Patricia A. Rosa, Philip E. Stewart, James L. Bono
Publikováno v:
Microbial Physiology. 6:29-40
In this report we describe two distinct approaches to develop new antibiotic resistance cassettes that allow for efficient selection of Borrelia burgdorferi transformants. The first approach utilizes fusions of borrelial flagellar promoters to antibi
Publikováno v:
Journal of Bacteriology. 182:2445-2452
Genetic studies in Borrelia burgdorferi have been hindered by the lack of a nonborrelial selectable marker. Currently, the only selectable marker is gyrB r , a mutated form of the chromosomal gyrB gene that encodes the B subunit of DNA gyrase and con
Autor:
Robert Child, Tara D. Wehrly, Tony W. Ng, Jean Celli, John J. Kupko, Sebenzile K. Myeni, Leigh A. Knodler, Stephen F. Porcella
Publikováno v:
PLoS Pathogens, Vol 9, Iss 8, p e1003556 (2013)
PLoS Pathogens
PLoS Pathogens
The intracellular pathogenic bacterium Brucella generates a replicative vacuole (rBCV) derived from the endoplasmic reticulum via subversion of the host cell secretory pathway. rBCV biogenesis requires the expression of the Type IV secretion system (
Autor:
Scott D. Kobayashi, Imran A. Babar, Robin M. Ireland, James M. Musser, Stephen F. Porcella, Stacy M. Ricklefs, Frank R. DeLeo, Morag R. Graham, Claire A. Johnson, Daniel E. Sturdevant, John R. Bailey, Patrick R. Shea, John J. Kupko, Kimmo Virtaneva, Donald J. Gardner, Fred A. Wright, Aaron B. Carmody, William T. Barry, Michael J. Parnell
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 107(10)
Relatively little is understood about the dynamics of global host–pathogen transcriptome changes that occur during bacterial infection of mucosal surfaces. To test the hypothesis that group A Streptococcus (GAS) infection of the oropharynx provokes
Autor:
Daniel E. Voth, Bruno W. S. Sobral, Paul A. Beare, James E. Samuel, Nathan Unsworth, John J. Kupko, Masako Andoh, Stephen F. Porcella, Robert A. Heinzen, Stacey D. Gilk, Anders Omsland, Kelly P. Williams
Publikováno v:
Infection and immunity. 77(2)
Genetically distinct isolates ofCoxiella burnetii, the cause of human Q fever, display different phenotypes with respect to in vitro infectivity/cytopathology and pathogenicity for laboratory animals. Moreover, correlations betweenC. burnetiigenomic
Autor:
Abdallah F, Elias, James L, Bono, John J, Kupko, Philip E, Stewart, Jonathan G, Krum, Patricia A, Rosa
Publikováno v:
Journal of molecular microbiology and biotechnology. 6(1)
In this report we describe two distinct approaches to develop new antibiotic resistance cassettes that allow for efficient selection of Borrelia burgdorferi transformants. The first approach utilizes fusions of borrelial flagellar promoters to antibi
Publikováno v:
Wiener klinische Wochenschrift. 110(24)
Borrelia burgdorferi, the agent of Lyme disease, has recently joined a growing number of micro-organisms for which the entire genomic sequence is known. Despite this wealth of information, little is known about the contribution of specific spirocheta