Zobrazeno 1 - 10
of 461
pro vyhledávání: '"J, Kruh"'
Publikováno v:
Progress in nuclear energy. Series 6 Biological sciences. 2(3)
Publikováno v:
Progress in nuclear energy. Series 6 Biological sciences. 2(3)
Publikováno v:
Comptes rendus des seances de la Societe de biologie et de ses filiales. 186(1-2)
Butyrate has a dramatic effect on transformed cells in culture. This effect disappears as soon as butyrate is removed from the medium. The other short chain fatty acids are much less effective. Butyrate produces an arrest of cell proliferation at the
Publikováno v:
Oncogene. 6(8)
We have hypothesized that the c-myc oncogene might promote DNA amplification. Resistance to methotrexate (MTX), a widely used cancer chemotherapeutic agent, often results from amplification of the gene coding for the target enzyme, dihydrofolate redu
Publikováno v:
médecine/sciences. 9:337
Publikováno v:
médecine/sciences. :1130
Publikováno v:
médecine/sciences. 6:359
Publikováno v:
Nucleic Acids Research. 17:8093-8099
The detection of point mutations correlated with diseases, in enzymatically amplified DNA sequences (Polymerase Chain Reaction), is currently performed by digestion of PCR products when an existing restriction site disappears at least in one allele o
Quasi-elastic light scattering study of salt induced conformational transitions of chromatin subunit
Publikováno v:
International Journal of Biological Macromolecules. 5:130-134
The translational diffusion coefficient D T of monodisperse solutions of 146 base pairs (bp) core particles was studied by the quasi-elastic light scattering technique. When the salinity was raised a change of D T from 1.9 × 10 −7 cm 2 s −1 to 3
Publikováno v:
Nucleic Acids Research. 6:1479-1493
The following observations concerning the DNA secondary structures in various nucleohistone complexes were made by infrared spectroscopy: 1/ in chromatin, chromatin extracted by 0.6 M NaCl, nucleosomes, and histone-DNA reconstituted complexes, the DN