Zobrazeno 1 - 10
of 130
pro vyhledávání: '"J, Kluk"'
Autor:
Ja-Young Jang, Inah Hwang, Heng Pan, Jun Yao, Lapo Alinari, Eddie Imada, Claudio Zanettini, Michael J. Kluk, Yizhe Wang, Yunkyoung Lee, Hua V. Lin, Xiangao Huang, Maurizio Di Liberto, Zhengming Chen, Karla V. Ballman, Lewis C. Cantley, Luigi Marchionni, Giorgio Inghirami, Olivier Elemento, Robert A. Baiocchi, Selina Chen-Kiang, Sandro Belvedere, Hongwu Zheng, Jihye Paik
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 24 (2022)
Targeting lineage-defined transcriptional dependencies has emerged as an effective therapeutic strategy in cancer treatment. Through screening for molecular vulnerabilities of mantle cell lymphoma (MCL), we identified a set of transcription factors (
Externí odkaz:
https://doaj.org/article/e15c9cf4b48849f098c33b46bf6b5433
Autor:
Yahya A. Al‐Ghamdi, Michael J. Kluk
Publikováno v:
eJHaem, Vol 3, Iss 3, Pp 1078-1079 (2022)
Externí odkaz:
https://doaj.org/article/27a19bbd21fe4232ac28f3b5e06bdec4
Autor:
Amanda Lopez, Sanjay Patel, Julia T. Geyer, Joelle Racchumi, Amy Chadburn, Paul Simonson, Madhu M. Ouseph, Giorgio Inghirami, Nuria Mencia-Trinchant, Monica L. Guzman, Alexandra Gomez-Arteaga, Sangmin Lee, Pinkal Desai, Ellen K. Ritchie, Gail J. Roboz, Wayne Tam, Michael J. Kluk
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
BackgroundNPM1 mutation status can influence prognosis and management in AML. Accordingly, clinical testing (i.e., RT-PCR, NGS and IHC) for mutant NPM1 is increasing in order to detect residual disease in AML, alongside flow cytometry (FC). However,
Externí odkaz:
https://doaj.org/article/f8a72db61b544a4bb1c2cd20d3ec0754
Autor:
Julia T. Geyer, Michael J. Kluk
Publikováno v:
Surgical Pathology Clinics. 16:411-421
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d3f5c5cfa533cc77108c5f652d7b634f
https://doi.org/10.1016/j.path.2023.01.012
https://doi.org/10.1016/j.path.2023.01.012
Autor:
Russell J.H. Ryan, Jelena Petrovic, Dylan M. Rausch, Yeqiao Zhou, Caleb A. Lareau, Michael J. Kluk, Amanda L. Christie, Winston Y. Lee, Daniel R. Tarjan, Bingqian Guo, Laura K.H. Donohue, Shawn M. Gillespie, Valentina Nardi, Ephraim P. Hochberg, Stephen C. Blacklow, David M. Weinstock, Robert B. Faryabi, Bradley E. Bernstein, Jon C. Aster, Warren S. Pear
Publikováno v:
Cell Reports, Vol 21, Iss 3, Pp 784-797 (2017)
Gain-of-function Notch mutations are recurrent in mature small B cell lymphomas such as mantle cell lymphoma (MCL) and chronic lymphocytic leukemia (CLL), but the Notch target genes that contribute to B cell oncogenesis are largely unknown. We perfor
Externí odkaz:
https://doaj.org/article/38f5e0dad5ea46838f521f8dde4cb919
Autor:
Keri Callegari, Sabyasachi Dash, Hiroki Uchida, Yuto Shingai, Catherine Liu, Anne Khodarkovskaya, Yunkyoung Lee, Akira Ito, Amanda Lopez, Tuo Zhang, Jenny Xiang, Michael J. Kluk, Teresa Sanchez
Publikováno v:
Proceedings of the National Academy of Sciences. 120
Stroke-induced cerebral microvascular dysfunction contributes to aggravation of neuronal injury and compromises the efficacy of current reperfusion therapies. Understanding the molecular alterations in cerebral microvessels in stroke will provide ori
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e6be650f0f7e5c68a3a0ce22fdf640aa
https://doi.org/10.1073/pnas.2205786120
https://doi.org/10.1073/pnas.2205786120
Publikováno v:
American Journal of Hematology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6bda0892ec2ecb0308d8015f21964be8
https://doi.org/10.1002/ajh.26873
https://doi.org/10.1002/ajh.26873
Autor:
Veronique Bataille, R Nambi, Ruth Murphy, Mario Falchi, A Bournot, R.C. E. Bowyer, Alessia Visconti, Claire J. Steves, Jonathan Wolf, Tim D. Spector, Niccolo Rossi, J Kluk, Susana Puig, Benjamin J. Murray, Sebastien Ourselin
Publikováno v:
British Journal of Dermatology
Background One of the challenging aspects of SARS-CoV-2 infection is its diverse multisystemic disease presentation. Objectives To evaluate the diagnostic value of cutaneous manifestations of SARS-CoV-2 infection and investigate their duration and ti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0722adb944aef15eb9356622f330e56
https://doi.org/10.1111/bjd.19807
https://doi.org/10.1111/bjd.19807
Publikováno v:
Current Hematologic Malignancy Reports. 15:350-359
Nucleophosmin (NPM1) mutations are encountered in myeloid neoplasia and are present in ~ 30% of de novo acute myeloid leukemia cases. This review summarizes features of mutant NPM1-related disease, with a particular emphasis on recent discoveries rel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2a267717acb9cb51507d899834eaea1
https://doi.org/10.1007/s11899-020-00592-3
https://doi.org/10.1007/s11899-020-00592-3
Autor:
Yahya A, Al-Ghamdi, Michael J, Kluk
Publikováno v:
EJHaem. 3(3)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d3c6a4267238b4f9ac0201931bb9d7f1
https://pubmed.ncbi.nlm.nih.gov/36051069
https://pubmed.ncbi.nlm.nih.gov/36051069