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of 6 504
pro vyhledávání: '"J, Kieffer"'
Akademický článek
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Publikováno v:
Cell Rep Med
Timothy Kieffer’s laboratory has contributed to our knowledge of islet biology and the development of cell-based strategies for insulin replacement for diabetes mellitus. In this Q&A, he discusses his journey in academia and industry and his perspe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cd397760e00807ce624e8873e8efabb0
https://pubmed.ncbi.nlm.nih.gov/35522093
https://pubmed.ncbi.nlm.nih.gov/35522093
Autor:
Jia Zhao, Shenghui Liang, Haoning Howard Cen, Yanjun Li, Robert K. Baker, Balwinder Ruprai, Guang Gao, Chloe Zhang, Huixia Ren, Chao Tang, Liangyi Chen, Yanmei Liu, Francis C. Lynn, James D. Johnson, Timothy J. Kieffer
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Remarkable advances in protocol development have been achieved to manufacture insulin-secreting islets from human pluripotent stem cells (hPSCs). Distinct from current approaches, we devised a tunable strategy to generate islet spheroids enr
Externí odkaz:
https://doaj.org/article/1bdf64aed5f74d41bf7cbec2f67ff56c
Akademický článek
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Publikováno v:
Buletinul Societății de Științe din București-România / Bulletin de la Société des Sciences de Bucarest-Roumanie, 1900 Jan 01. 9(1), 143-150.
Externí odkaz:
https://www.jstor.org/stable/43770876
Autor:
Diepiriye G. Iworima, Robert K. Baker, Cara Ellis, Chris Sherwood, Lisa Zhan, Alireza Rezania, James M. Piret, Timothy J. Kieffer
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-27 (2024)
Abstract Background Diabetes is a disease affecting over 500 million people globally due to insulin insufficiency or insensitivity. For individuals with type 1 diabetes, pancreatic islet transplantation can help regulate their blood glucose levels. H
Externí odkaz:
https://doaj.org/article/eef5378a3b1e42df99f87e9d84023768
Autor:
Mitchell J. S. Braam, Jia Zhao, Shenghui Liang, Shogo Ida, Nick K. Kloostra, Diepiriye G. Iworima, Mei Tang, Robert K. Baker, Nina Quiskamp, James M. Piret, Timothy J. Kieffer
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-17 (2023)
Abstract The generation of functional β-cells from human pluripotent stem cells (hPSCs) for cell replacement therapy and disease modeling of diabetes is being investigated by many groups. We have developed a protocol to harvest and aggregate hPSC-de
Externí odkaz:
https://doaj.org/article/fad7c7701c714b55ac516ffdf75998a9
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 11 (2023)
Introduction: Human pluripotent stem cells (hPSCs) provide many opportunities for application in regenerative medicine due to their ability to differentiate into cells from all three germ layers, proliferate indefinitely, and replace damaged or dysfu
Externí odkaz:
https://doaj.org/article/ea6232bfd13f4492920ebb3a18c3c90b
Autor:
Jeffery L. Heileson, Steven B. Machek, Dillon R. Harris, Sara Tomek, Leticia C. de Souza, Adam J. Kieffer, Nicholas D. Barringer, Andrew Gallucci, Jeffrey S. Forsse, LesLee K. Funderburk
Publikováno v:
Journal of the International Society of Sports Nutrition, Vol 20, Iss 1 (2023)
Background Resistance exercise training (RET) is a common and well-established method to induce hypertrophy and improvement in strength. Interestingly, fish oil supplementation (FOS) may augment RET-induced adaptations. However, few studies have been
Externí odkaz:
https://doaj.org/article/7609500c8119402e8a3668d43b7ee9cc