Zobrazeno 1 - 10
of 156
pro vyhledávání: '"J, Kempen"'
Publikováno v:
mSystems, Vol 9, Iss 8 (2024)
ABSTRACT Microalgal microbiomes play vital roles in the growth and health of their host, however, their composition and functions remain only partially characterized, especially across microalgal phyla. In this study, a natural seawater microbiome wa
Externí odkaz:
https://doaj.org/article/9019547c77e346dba3ccb1e12a7a92a6
Autor:
Laura Louise Lindqvist, Scott A. Jarmusch, Eva C. Sonnenschein, Mikael Lenz Strube, Janie Kim, Maike Wennekers Nielsen, Paul J. Kempen, Erwin M. Schoof, Sheng-Da Zhang, Lone Gram
Publikováno v:
mSphere, Vol 8, Iss 1 (2023)
ABSTRACT In the marine environment, surface-associated bacteria often produce an array of antimicrobial secondary metabolites, which have predominantly been perceived as competition molecules. However, they may also affect other hallmarks of surface-
Externí odkaz:
https://doaj.org/article/3d2f46eddfe04f64be71823e7bc0f9f4
Autor:
Emanuel Sporer, Christian B. M. Poulie, Sture Lindegren, Emma Aneheim, Holger Jensen, Tom Bäck, Paul J. Kempen, Andreas Kjaer, Matthias M. Herth, Andreas I. Jensen
Publikováno v:
Journal of Nanotheranostics, Vol 2, Iss 4, Pp 196-207 (2021)
Targeted α-therapy (TAT) can eradicate tumor metastases while limiting overall toxicity. One of the most promising α-particle emitters is astatine-211 (211At). However, 211At-carbon bonds are notoriously unstable in vivo and no chelators are availa
Externí odkaz:
https://doaj.org/article/fc6d21baaf7241e9801fd9856d9fa10c
Autor:
Arjen Weller, Morten B. Hansen, Rodolphe Marie, Adam C. Hundahl, Casper Hempel, Paul J. Kempen, Henrik L. Frandsen, Ladan Parhamifar, Jannik B. Larsen, Thomas L. Andresen
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 10 (2022)
Unsuccessful clinical translation of orally delivered biological drugs remains a challenge in pharmaceutical development and has been linked to insufficient mechanistic understanding of intestinal drug transport. Live cell imaging could provide such
Externí odkaz:
https://doaj.org/article/e425fcb8956a43f1a5293643c45fd42a
Autor:
Ramses Gallegos-Monterrosa, Mathilde Nordgaard Christensen, Tino Barchewitz, Sonja Koppenhöfer, B. Priyadarshini, Balázs Bálint, Gergely Maróti, Paul J. Kempen, Anna Dragoš, Ákos T. Kovács
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-12 (2021)
Ramses Gallegos-Monterrosa, Mathilde Nordgaard Christensen, and colleagues investigate how a single or double deletion of the rap-phr genes, parts of peptide-based quorum sensing systems, impacts the sporulation and biofilm formation of B. subtilis u
Externí odkaz:
https://doaj.org/article/b6d4495effed4defa767a6e7cf523350
Autor:
Rasmus Münter, Martin Bak, Esben Christensen, Paul J. Kempen, Jannik B. Larsen, Kasper Kristensen, Ladan Parhamifar, Thomas L. Andresen
Publikováno v:
Acta Biomaterialia. 144:96-108
Stimulation of monocytes with immunomodulating agents can harness the immune system to treat a long range of diseases, including cancers, infections and autoimmune diseases. To this end we aimed to develop a monocyte-targeting delivery platform based
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5efd93902ae3dc9d4952e219adeccd1f
https://doi.org/10.1016/j.actbio.2022.03.029
https://doi.org/10.1016/j.actbio.2022.03.029
Autor:
Carmen Radeke, Raphaël Pons, Marko Mihajlovic, Jonas R. Knudsen, Sarkhan Butdayev, Paul J. Kempen, Charis-Patricia Segeritz, Thomas L. Andresen, Christian K. Pehmøller, Thomas E. Jensen, Johan U. Lind
Publikováno v:
ACS applied materialsinterfaces.
For three-dimensional (3D) bioprinting to fulfill its promise and enable the automated fabrication of complex tissue-mimicking constructs, there is a need for developing bioinks that are not only printable and biocompatible but also have integrated c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfe8bb0dbc686d2726d2905969d6e7ae
https://pubmed.ncbi.nlm.nih.gov/36598781
https://pubmed.ncbi.nlm.nih.gov/36598781
Autor:
Kasper B. Johnsen, Adrian Klepe, Charlotte Goldeman, Annette Burkhart, Paul J. Kempen, Morten Nielsen, Peter L. Møller, Dora V. Lipka, Maj S. Thomsen, Mette Nyegaard, Andrea E. Tóth, Thomas Lars Andresen, Andras Harazin, Torben Moos, Birger Brodin, Hans C. Helms
Publikováno v:
Toth, A E, Helms, H C, Harazin, A, Johnsen, K B, Goldeman, C, Burkhart, A, Thomsen, M S, Kempen, P J, Klepe, A, Lipka, D V, Møller, P L, Andresen, T L, Nyegaard, M, Moos, T, Brodin, B & Nielsen, M S 2022, ' Sortilin regulates blood-brain barrier integrity ', The FEBS Journal, vol. 289, no. 4, pp. 1062-1079 . https://doi.org/10.1111/febs.16225
Toth, A E, Helms, H C, Harazin, A, Johnsen, K B, Goldeman, C, Burkhart, A, Thomsen, M S, Kempen, P J, Klepe, A, Lipka, D V, Møller, P L, Andresen, T L, Nyegaard, M, Moos, T, Brodin, B & Nielsen, M S 2022, ' Sortilin regulates blood-brain barrier integrity ', FEBS Journal, vol. 289, no. 4, pp. 1062-1079 . https://doi.org/10.1111/febs.16225
Toth, A E, Helms, H C, Harazin, A, Johnsen, K B, Goldeman, C, Burkhart, A, Thomsen, M S, Kempen, P J, Klepe, A, Lipka, D V, Møller, P L, Andresen, T L, Nyegaard, M, Moos, T, Brodin, B & Nielsen, M S 2022, ' Sortilin regulates blood-brain barrier integrity ', FEBS Journal, vol. 289, no. 4, pp. 1062-1079 . https://doi.org/10.1111/febs.16225
Brain homeostasis depends on the existence of the blood-brain barrier (BBB). Despite decades of research, the factors and signalling pathways for modulating and maintaining BBB integrity are not fully elucidated. Here, we characterize the expression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f26d4f7d376ec61a77c2ecbafb7618b5
https://doi.org/10.1111/febs.16225
https://doi.org/10.1111/febs.16225
Autor:
Holger Jensen, Matthias M. Herth, Emma Aneheim, Andreas Kjaer, Paul J. Kempen, Andreas Tue Ingemann Jensen, Emanuel Sporer, Tom Bäck, Sture Lindegren, Christian B. M. Poulie
Publikováno v:
Sporer, E, Poulie, C B M, Lindegren, S, Aneheim, E, Jensen, H, Bäck, T, Kempen, P J, Kjaer, A, Herth, M M & Jensen, A I 2021, ' Surface Adsorption of the Alpha-Emitter Astatine-211 to Gold Nanoparticles Is Stable In Vivo and Potentially Useful in Radionuclide Therapy ', Journal of Nanotheranostics, vol. 2, no. 4, pp. 196-207 . https://doi.org/10.3390/jnt2040012
Journal of Nanotheranostics, Vol 2, Iss 12, Pp 196-207 (2021)
Capital Region of Denmark
Journal of Nanotheranostics, Vol 2, Iss 12, Pp 196-207 (2021)
Capital Region of Denmark
Targeted α-therapy (TAT) can eradicate tumor metastases while limiting overall toxicity. One of the most promising α-particle emitters is astatine-211 (211At). However, 211At-carbon bonds are notoriously unstable in vivo and no chelators are availa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6af0f49e9d15019e6a3be033660fa7f
https://doi.org/10.3390/jnt2040012
https://doi.org/10.3390/jnt2040012
Autor:
Dwight R. Stoll, Gudrun Kainz, Tina A. Dahlseid, Trevor J. Kempen, Tyler Brau, Bob W.J. Pirok
Publikováno v:
Journal of Chromatography A, 1678:463350. Elsevier
Efforts to model and simulate various aspects of liquid chromatography (LC) separations (e.g., retention, selectivity, peak capacity, injection breakthrough) depend on experimental retention measurements to use as the basis for the models and simulat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22655ef94017859cfe767b69ba11e1be
https://pubmed.ncbi.nlm.nih.gov/35896047
https://pubmed.ncbi.nlm.nih.gov/35896047