Zobrazeno 1 - 10
of 524
pro vyhledávání: '"J, Kallio"'
Publikováno v:
npj Materials Degradation, Vol 6, Iss 1, Pp 1-8 (2022)
Abstract The increasing use of bioethanol fuel, as a promising carbon-neutral alternative to petroleum-based gasoline, has raised concerns on compatibility issues between bioethanol and the polymer components used in the automotive fuel system. Here,
Externí odkaz:
https://doaj.org/article/491322f5123446539a197fddfad43cda
Autor:
Sofia Aakko, Anne Hege Straume, Einar Elvbakken Birkeland, Ping Chen, Xi Qiao, Per Eystein' 'Lønning, Marko J. Kallio
Publikováno v:
Translational Oncology, Vol 12, Iss 1, Pp 170-179 (2019)
Taxanes are chemotherapeutic agents used in the treatment of solid tumors, particularly of breast, ovarian, and lung origin. However, patients show divergent therapy responses, and the molecular determinants of taxane sensitivity have remained elusiv
Externí odkaz:
https://doaj.org/article/882708b2dee8437db0dcdf260e5b1495
Autor:
Marko J, Kallio, Viktoriia, Starokozhko, Eleonora, Agricola, Manja, Burggraf, Anne, Heß, Wolfgang, Ballensiefen, Wiebke, Löbker, Yoana, Nuevo, Anna M G, Pasmooij, Peter G M, Mol
Publikováno v:
Clinical Pharmacology and Therapeutics, 113(2), 349-359. Nature Publishing Group
Important discoveries by academic drug developers hold the promise of bringing innovative treatments that address unmet medical needs to the market. However, the drug development process has proved to be challenging and demanding for academic researc
Autor:
Marko J. Kallio, Antti Poso, Lila Kallio, Arne Lindqvist, Pasi Halonen, Elvira Hukasova, Pekka Tiikkainen, Elli Narvi, Jonathan Rehnberg, Leena J. Laine, Jenni H.E. Mäki-Jouppila
Supplemental Movie 1. Cent-1 treated HeLa H2B-GFP mCherry-tubulin cells arrest in mitosis for several hours with misaligned chromosomes, followed by cell death or abnormal exit from M phase. The cell on the left hand side forms a multipolar spindle a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::048e2331a542dfa6a6340a8df14f34ef
https://doi.org/10.1158/1535-7163.22500160
https://doi.org/10.1158/1535-7163.22500160
Autor:
Pekka J. Kallio, Murali Ramachandra, Nanduri Srinivas, Ravi K. Ujjinamatada, Subhendu Mukherjee, Samiulla Dhodheri, Thomas Anthony, Nagaraj Gowda, Rashmi Nair, Jiju Mani, Raghuveer K. Ramachandra, Kishore Narayanan, Shekar Chelur, Srinivasan Rajagopalan, Susanta Samajdar, Timo Korjamo, Riikka Oksala, Stefan Karlsson, Gerd Wohlfahrt, Tero Linnanen, Mari L. Björkman, Tarja Ikonen, Anu-Maarit Moilanen, Tim H. Holmström
Supplementary table S1 shows the effect of ODM-203 in a large kinase panel. Supplementary figure S1 shows how ODM-203 is synthesized. Supplementary figure S2 shows the effect of ODM-203 on FRS2 phosphorylation. Supplement figure S3 shows the effect o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01a4b40ece62b019671a48c99c70cd8b
https://doi.org/10.1158/1535-7163.22505722
https://doi.org/10.1158/1535-7163.22505722
Autor:
Marko J. Kallio, Antti Poso, Lila Kallio, Arne Lindqvist, Pasi Halonen, Elvira Hukasova, Pekka Tiikkainen, Elli Narvi, Jonathan Rehnberg, Leena J. Laine, Jenni H.E. Mäki-Jouppila
Mitosis is an attractive target for the development of new anticancer drugs. In a search for novel mitotic inhibitors, we virtually screened for low molecular weight compounds that would possess similar steric and electrostatic features, but differen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01e66c27df748880b1259d18eaba3507
https://doi.org/10.1158/1535-7163.c.6536371.v1
https://doi.org/10.1158/1535-7163.c.6536371.v1
Autor:
Pekka J. Kallio, Murali Ramachandra, Nanduri Srinivas, Ravi K. Ujjinamatada, Subhendu Mukherjee, Samiulla Dhodheri, Thomas Anthony, Nagaraj Gowda, Rashmi Nair, Jiju Mani, Raghuveer K. Ramachandra, Kishore Narayanan, Shekar Chelur, Srinivasan Rajagopalan, Susanta Samajdar, Timo Korjamo, Riikka Oksala, Stefan Karlsson, Gerd Wohlfahrt, Tero Linnanen, Mari L. Björkman, Tarja Ikonen, Anu-Maarit Moilanen, Tim H. Holmström
Alterations in the gene encoding for the FGFR and upregulation of the VEGFR are found often in cancer, which correlate with disease progression and unfavorable survival. In addition, FGFR and VEGFR signaling synergistically promote tumor angiogenesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b0ba784729eaeca665669c7e27a87040
https://doi.org/10.1158/1535-7163.c.6538162.v1
https://doi.org/10.1158/1535-7163.c.6538162.v1
Akademický článek
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Autor:
Leena J. Laine, Jenni H.E. Mäki-Jouppila, Emma Kutvonen, Pekka Tiikkainen, Thomas K.M. Nyholm, Jerry F. Tien, Neil T. Umbreit, Ville Härmä, Lila Kallio, Trisha N. Davis, Charles L. Asbury, Antti Poso, Gary J. Gorbsky, Marko J. Kallio
Publikováno v:
Oncoscience
Hec1 (Highly expressed in cancer 1) resides in the outer kinetochore where it works to facilitate proper kinetochore-microtubule interactions during mitosis. Hec1 is overexpressed in various cancers and its expression shows correlation with high tumo
Autor:
Kati M. Salla, Heta A. Turunen, Ira J. Kallio-Kujala, Vuokko Pekkola, Daniela C. Casoni, Jaan Lepajoe, Pia Björkenheim, Marja R. Raekallio, Outi Vainio
Publikováno v:
Salla, Kati M; Turunen, Heta A; Kallio-Kujala, Ira J; Pekkola, Vuokko; Casoni, Daniela C; Lepajoe, Jaan; Björkenheim, Pia; Raekallio, Marja R; Vainio, Outi (2022). Effects of vatinoxan in dogs premedicated with medetomidine and butorphanol followed by sevoflurane anaesthesia: a randomized clinical study. Veterinary anaesthesia and analgesia, 49(6), pp. 563-571. Elsevier 10.1016/j.vaa.2022.08.002
Publisher Copyright: © 2022 The Author(s) Objective: To investigate effects of vatinoxan in dogs, when administered as intravenous (IV) premedication with medetomidine and butorphanol before anaesthesia for surgical castration. Study design: A rando
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72edaf67886f55d0bf2f781c3243df01
https://boris.unibe.ch/173028/1/1-s2.0-S1467298722001295-main.pdf
https://boris.unibe.ch/173028/1/1-s2.0-S1467298722001295-main.pdf