Zobrazeno 1 - 10
of 547
pro vyhledávání: '"J, Janin"'
Publikováno v:
International Journal of Pharmaceutics. 331:148-152
In a previous study, we have shown that cidofovir (CDV) and azidothymidine-triphosphate (AZT-TP) were poorly encapsulated in poly(iso-butylcyanoacrylate) (PIBCA) aqueous-core nanocapsules. This was attributed to the rapid leakage of these small and h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09c09f1638cd4271833b9f2f87644db1
https://doi.org/10.1016/j.ijpharm.2006.10.031
https://doi.org/10.1016/j.ijpharm.2006.10.031
Publikováno v:
International Journal of Pharmaceutics. 324:37-42
Nucleoside analogues are widely used in the treatment of various viral infections. However, the poor in vivo conversion of the nucleoside analogues like azidothymidine (AZT) into their active triphosphate nucleotide counterpart limits their pharmacol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::476f101a4f0e4558c4ffd3b910057246
https://doi.org/10.1016/j.ijpharm.2006.07.006
https://doi.org/10.1016/j.ijpharm.2006.07.006
Autor:
J, Janin
Publikováno v:
Proteins: Structure, Function, and Genetics. 21:30-39
The affinity of two molecules for each other and its temperature dependence are determined by the change in enthalpy, free enthalpy, entropy, and heat capacity upon dissociation. As we know the forces that stabilize protein-protein or protein-DNA ass
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a67e7548d51efa6f1a97b666c924bdb
https://doi.org/10.1002/prot.340210105
https://doi.org/10.1002/prot.340210105
Publikováno v:
Journal of Applied Crystallography. 27:622-626
TAOS is a fully automatic system for protein crystallization. Based on a central five-axis robot, it performs vapour-diffusion experiments in commercially available plates with three types of drop geometry, i.e. hanging, sitting or sandwich drops. It
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c8fb834df3fe6441e64277e69a48c371
https://doi.org/10.1107/s0021889894000543
https://doi.org/10.1107/s0021889894000543
Autor:
Shoshana J. Wodak, Van Belle D, De Maeyer M, van Tilbeurgh H, John A. Jenkins, J. Janin, Félix A. Rey, Ignace Lasters, M Chiadmi, Lauwereys M
Publikováno v:
Biochemistry. 31:5449-5458
The structure and function of the xylose (glucose) isomerase from Actinoplanes missouriensis have been analyzed by X-ray crystallography and site-directed mutagenesis after cloning and overexpression in Escherichia coli. The crystal structure of wild
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07ec8671a764a613c89ff49bac56db2f
https://doi.org/10.1021/bi00139a005
https://doi.org/10.1021/bi00139a005
Autor:
M Chiadmi, John A. Jenkins, H van Tilbeurgh, J. Janin, Anne-Marie Lambeir, Shoshana J. Wodak, Nadir Mrabet
Publikováno v:
Biochemistry. 31:5467-5471
Aldose-ketose isomerization by xylose isomerase requires bivalent cations such as Mg2+, Mn2+, or Co2+. The active site of the enzyme from Actinoplanes missouriensis contains two metal ions that are involved in substrate binding and in catalyzing a hy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::985d8f6bd83e81f20addb6f5ab86ad58
https://doi.org/10.1021/bi00139a007
https://doi.org/10.1021/bi00139a007
Autor:
Dominique Liger, Lionel Trésaugues, Nabila Bettache, Cong-Zhao Zhou, Herman van Tilbeurgh, Robert Aufrère, Ilham Aboulfath, J. Janin, Bruno Collinet, Karine Blondeau, Sophie Quevillon-Cheruel, Nicolas Leulliot, Gilles Henckes, A. Poupon, Philippe Minard
Publikováno v:
Methods in Molecular Biology ISBN: 9781588292926
The South-Paris Yeast Structural Genomics Pilot Project (http://www.genomics.eu.org) aims at systematically expressing, purifying, and determining the three-dimensional structures of Saccharomyces cerevisiae proteins. We have already cloned 240 yeast
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1abb98b1afc23b25028a69ef736c106
https://doi.org/10.1385/1-59745-209-2:21
https://doi.org/10.1385/1-59745-209-2:21
Autor:
M, Graille, P, Meyer, N, Leulliot, I, Sorel, J, Janin, H, Van Tilbeurgh, S, Quevillon-Cheruel
Publikováno v:
Biochimie. 87(8)
Ribose-5-phosphate isomerase A has an important role in sugar metabolism by interconverting ribose-5-phosphate and ribulose-5-phosphate. This enzyme is ubiquitous and highly conserved among the three kingdoms of life. We have solved the 2.1 A resolut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c503f41a990500d085c3248759d82cb5
https://pubmed.ncbi.nlm.nih.gov/16054529
https://pubmed.ncbi.nlm.nih.gov/16054529
Publikováno v:
Journal of bioenergetics and biomembranes. 32(3)
Three-dimensional structures are known from X-ray studies of the nucleoside diphosphate (NDP) kinase of many organisms from bacteria to human. All NDP kinases have subunits of about 150 residues with a very similar fold based on the alphabeta sandwic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::dce39eb79cc9bf39e41e431917ecc4c0
https://pubmed.ncbi.nlm.nih.gov/11768305
https://pubmed.ncbi.nlm.nih.gov/11768305
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