Zobrazeno 1 - 10
of 41
pro vyhledávání: '"J, Iseli"'
Autor:
Tristan J Iseli, Nigel Turner, Xiao-Yi Zeng, Gregory J Cooney, Edward W Kraegen, Sheng Yao, Yang Ye, David E James, Ji-Ming Ye
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e62309 (2013)
We recently showed that bitter melon-derived triterpenoids (BMTs) activate AMPK and increase GLUT4 translocation to the plasma membrane in vitro, and improve glucose disposal in insulin resistant models in vivo. Here we interrogated the mechanism by
Externí odkaz:
https://doaj.org/article/d67835f8a4ae4b2bb01009436d88b823
Autor:
Xiao-Yi Zeng, Yi-Ping Wang, James Cantley, Tristan J Iseli, Juan Carlos Molero, Bronwyn D Hegarty, Edward W Kraegen, Yang Ye, Ji-Ming Ye
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e42115 (2012)
The present study investigated the chronic efficacy of oleanolic acid (OA), a triterpenoid selected from our recent screening, on hyperglycemia in type-2 diabetic mice. C57BL/6J mice were fed a high-fat diet followed by low doses of streptozotocin to
Externí odkaz:
https://doaj.org/article/4846e6d2445b4bdd9e37c2b07c3cd66d
Autor:
Lu-Ping Ren, Stanley M H Chan, Xiao-Yi Zeng, D Ross Laybutt, Tristan J Iseli, Ruo-Qiong Sun, Edward W Kraegen, Gregory J Cooney, Nigel Turner, Ji-Ming Ye
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e30816 (2012)
Mitochondrial dysfunction and endoplasmic reticulum (ER) stress have been implicated in hepatic steatosis and insulin resistance. The present study investigated their roles in the development of hepatic steatosis and insulin resistance during de novo
Externí odkaz:
https://doaj.org/article/955ff7c56eb041cb93ac77a8900849de
Autor:
Badr Alzahrani, Mehdi Ramezani-Moghadam, Miriam Wankell, Tristan J. Iseli, Eun Jin Sun, Vikki Ho, Jacob George, Liang Qiao, Lionel Hebbard
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1864:700-708
Activation of the adiponectin (APN) signaling axis retards liver fibrosis. However, understanding of the role of AdipoR1 and AdipoR2 in mediating this response is still rudimentary. Here, we sought to elucidate the APN receptor responsible for limiti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec3a13193fd9b8830bdda0125d69ff77
https://doi.org/10.1016/j.bbadis.2017.12.012
https://doi.org/10.1016/j.bbadis.2017.12.012
Autor:
Jianhua Wang, Saeed Esmaili, Aimin Xu, Mehdi Ramezani-Moghadam, Liangshuo Hu, Lin Su, Zhixia Dong, Jacob George, Tristan J. Iseli
Publikováno v:
Journal of Molecular Medicine. 93:1327-1339
Adiponectin protects against liver fibrosis, but the mechanisms have not been fully elucidated. Here, we showed that adiponectin upregulated inducible nitric oxide synthase (iNOS) messenger RNA (mRNA) and protein expression in hepatic non-parenchymal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34eff337bc9dc15901dc36b9869038ea
https://doi.org/10.1007/s00109-015-1313-z
https://doi.org/10.1007/s00109-015-1313-z
Autor:
Roslyn Vongsuvanh, Geoffrey W. McCaughan, Tristan J. Iseli, David van der Poorten, Jacob George, Simone I. Strasser
Publikováno v:
PLoS ONE
PLoS ONE, Vol 11, Iss 5, p e0155800 (2016)
PLoS ONE, Vol 11, Iss 5, p e0155800 (2016)
UNLABELLED:Robust biomarkers for population-level hepatocellular carcinoma (HCC) surveillance are lacking. We compared serum midkine (MDK), dickkopf-1 (DKK1), osteopontin (OPN) and AFP for HCC diagnosis in 86 HCC patients matched to 86 cirrhotics, 86
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58cfc3a28dfb5893b6f140d50ada3755
http://europepmc.org/articles/PMC4878793
http://europepmc.org/articles/PMC4878793
Autor:
Amanda E. Brandon, Andrew J. Hoy, Lauren E. Wright, Asish K. Saha, Bronwyn D. Hegarty, X. Julia Xu, Gregory J. Cooney, Tristan J. Iseli, Neil B. Ruderman, Edward W. Kraegen, Nigel Turner
Publikováno v:
Archives of Biochemistry and Biophysics. 509:133-141
Glucose infusion into rats causes skeletal muscle insulin resistance that initially occurs without changes in insulin signaling. The aim of the current study was to prolong glucose infusion and evaluate other events associated with the transition to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ca7c4074c6e822646034f3720a9f75b
https://doi.org/10.1016/j.abb.2011.03.008
https://doi.org/10.1016/j.abb.2011.03.008
Publikováno v:
The Indian Journal of Pediatrics. 77:547-550
To evaluate the relationship between waist-to-height ratio (WHtR) and glucose and lipid metabolism in Han adolescents aged 13-15 years.A study was conducted on 1665 Han adolescents aged 13-15 years. Measurements included height, weight, waist circumf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::998bfebc5989d8aa58985096db9a8fa2
https://doi.org/10.1007/s12098-010-0054-9
https://doi.org/10.1007/s12098-010-0054-9
Autor:
Bryce J. W. van Denderen, Bruce E. Kemp, Tristan J. Iseli, Belinda J. Michell, Sheena Wee, Michael F. Bailey, Lee A. Witters, Mark R. Walter, David Stapleton, S. Lance Macaulay, Frosa Katsis, Laura A. Castelli, Jonathan S. Oakhill
Publikováno v:
Journal of Biological Chemistry. 283:4799-4807
AMP-activated protein kinase (AMPK) plays multiple roles in the body's overall metabolic balance and response to exercise, nutritional stress, hormonal stimulation, and the glucose-lowering drugs metformin and rosiglitazone. AMPK consists of a cataly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0a4eea2b96d96fd738981babf883700d
https://doi.org/10.1074/jbc.m708298200
https://doi.org/10.1074/jbc.m708298200
Publikováno v:
Diabetes Research and Clinical Practice. 37:157-164
To be the master of their disease and not its slave is the ultimate goal of many patients with diabetes. Intensified functional insulin therapy (FIT) helps to establish this goal by an intensive patient education: each patient learns in five small-gr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::372b8adcf49943ff1ccf82c0ec75c6a1
https://doi.org/10.1016/s0168-8227(97)00071-5
https://doi.org/10.1016/s0168-8227(97)00071-5