Zobrazeno 1 - 10
of 16 923
pro vyhledávání: '"J, Howard"'
Autor:
Steven J. Howard, E. Vasseleu, L. Mushahwar, S. Mallawaarachchi, C. Neilsen-Hewett, N. Day, E. C. Melhuish, K. E. Williams
Publikováno v:
BMC Psychology, Vol 12, Iss 1, Pp 1-12 (2024)
Abstract Background Enough is known about self-regulation to establish it as a priority target for education and intervention efforts beginning in early childhood, yet not enough to meaningfully and reliably alter developmental trajectories. Rather t
Externí odkaz:
https://doaj.org/article/9dff32803d574fb3a6af956cdc3eed7b
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract α7 nicotinic acetylcholine receptors (nAChRs) are homopentameric ligand-gated ion channels with critical roles in the nervous system. Recent studies have resolved and functionally annotated closed, open, and desensitized states of these rec
Externí odkaz:
https://doaj.org/article/21ddf1317baa4ea4841d610b8876a006
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract ρ-type γ-aminobutyric acid-A (GABAA) receptors are widely distributed in the retina and brain, and are potential drug targets for the treatment of visual, sleep and cognitive disorders. Endogenous neuroactive steroids including β-estradio
Externí odkaz:
https://doaj.org/article/670fbe13ae4d4d80830997f0f83876d5
Autor:
James Unwin, Weronika O. Razmus, Felix Allum, James R. Harries, Yoshiaki Kumagai, Kiyonobu Nagaya, Mathew Britton, Mark Brouard, Philip Bucksbaum, Mizuho Fushitani, Ian Gabalski, Tatsuo Gejo, Paul Hockett, Andrew J. Howard, Hiroshi Iwayama, Edwin Kukk, Chow-shing Lam, Joseph McManus, Russell S. Minns, Akinobu Niozu, Sekito Nishimuro, Johannes Niskanen, Shigeki Owada, James D. Pickering, Daniel Rolles, James Somper, Kiyoshi Ueda, Shin-ichi Wada, Tiffany Walmsley, Joanne L. Woodhouse, Ruaridh Forbes, Michael Burt, Emily M. Warne
Publikováno v:
ACS Physical Chemistry Au, Vol 4, Iss 6, Pp 620-631 (2024)
Externí odkaz:
https://doaj.org/article/12993092df17459a86adc3e103eda879
Autor:
Xiaolong Gao, Han-I Yeh, Zhengrong Yang, Chen Fan, Fan Jiang, Rebecca J. Howard, Erik Lindahl, John C. Kappes, Tzyh-Chang Hwang
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Loss-of-function mutations of the CFTR gene cause the life-shortening genetic disease cystic fibrosis (CF), whereas overactivity of CFTR may lead to secretory diarrhea and polycystic kidney disease. While effective drugs targeting the CFTR p
Externí odkaz:
https://doaj.org/article/86b783d0ca63434bb3730316e05145d3
Autor:
SM Bollard, J Howard, C Casalou, BS Kelly, K O'Donnell, G Fenn, J O'Reilly, R Milling, M Shields, M Wilson, A Ajaykumar, K Triana, K Wynne, DJ Tobin, PA Kelly, A McCann, SM Potter
Publikováno v:
Translational Oncology, Vol 50, Iss , Pp 102152- (2024)
Background: Plasma-derived Extracellular Vesicles (EVs) have been suggested as novel biomarkers in melanoma, due to their ability to reflect the cell of origin and ease of collection. This study aimed to identify novel EV biomarkers that can discrimi
Externí odkaz:
https://doaj.org/article/9410ced3e557417bba370bd9b46d0392
Autor:
E. Cortés Vicente, M. Freimer, A. Genge, C. Hewamadduma, J. Howard Jr., Y. Hussain, A. Maniaol, R. Mantegazza, K. Utsugisawa, T. Vu, M. Weiss, B. Boroojerdi, P. Duda, F. Grimson, M. Vanderkelen, M. Leite
Publikováno v:
Neurology Perspectives, Vol 4, Iss , Pp 246- (2024)
Externí odkaz:
https://doaj.org/article/8f2373ed172743d28e8ea3e0e9802c9a
Autor:
Sanjula D. Singh, Cyprien A. Rivier, Keren Papier, Zeina Chemali, Leidys Gutierrez-Martinez, Livia Parodi, Ernst Mayerhofer, Jasper Senff, Santiago Clocchiatti-Tuozzo, Courtney Nunley, Amy Newhouse, An Ouyang, M. Brandon Westover, Rudolph E. Tanzi, Ronald M. Lazar, Aleksandra Pikula, Sarah Ibrahim, H. Bart Brouwers, Virginia J. Howard, George Howard, Nirupama Yechoor, Thomas Littlejohns, Kevin N. Sheth, Jonathan Rosand, Gregory Fricchione, Christopher D. Anderson, Guido J. Falcone
Publikováno v:
Frontiers in Psychiatry, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/97936073fee1465093218f6396189b30
Autor:
Mike English, Alex Brown, James Marangou, Shobhana Nagraj, Jonathan Carapetis, Bo Remenyi, Karla Canuto, Jeffrey W Cannon, Paul Burgess, Peter Morris, Alex Kaethner, Anna Ralph, Jennifer Yan, Vicki Wade, Daniel Engelman, Andrew Steer, Judith M Katzenellenbogen, Bart J Currie, Benjamin Jones, Gavin Wheaton, David Simon, Holger Unger, Graham Hillis, Natasha J Howard, Joshua R Francis, Emma Haynes, Maida Stewart, Salvador Amaral, Alice Mitchell, Anferida Fernandes Monteiro, Marisa Gilles, Herculano Seixas, Joaquina Maurays, Jade Neave, Chantelle Pears, Meghan Bailey, Maria Tanesi, Helder Neto, Jacqui Williamson, Jessica de Dassel, Simon Slota-Kan
Publikováno v:
BMJ Open, Vol 14, Iss 10 (2024)
Introduction Rheumatic heart disease (RHD) is underdiagnosed globally resulting in missed treatment opportunities and adverse clinical outcomes. We describe the protocol for a study which aims to co-design, implement and conduct an evaluation of a ta
Externí odkaz:
https://doaj.org/article/b4ab7a24c91c41949d475bc71b6d0b21