Zobrazeno 1 - 10
of 990
pro vyhledávání: '"J, Hone"'
Autor:
Jorge L. B. Neves, Cristoval Urcino, Kevin Chase, Cheryl Dowell, Arik J. Hone, David Morgenstern, Victor M. Chua, Iris Bea L. Ramiro, Julita S. Imperial, Lee S. Leavitt, Jasmine Phan, Fernando A. Fisher, Maren Watkins, Shrinivasan Raghuraman, Jortan O. Tun, Beatrix M. Ueberheide, J. Michael McIntosh, Vitor Vasconcelos, Baldomero M. Olivera, Joanna Gajewiak
Publikováno v:
Marine Drugs, Vol 22, Iss 3, p 118 (2024)
The venom of cone snails has been proven to be a rich source of bioactive peptides that target a variety of ion channels and receptors. α-Conotoxins (αCtx) interact with nicotinic acetylcholine receptors (nAChRs) and are powerful tools for investig
Externí odkaz:
https://doaj.org/article/eb10793f322b4e929d26fb3a31f6499e
Autor:
Arik J. Hone, J. Michael McIntosh
Publikováno v:
Pharmacological Research, Vol 190, Iss , Pp 106715- (2023)
Nicotinic acetylcholine receptors (nAChRs) have been historically defined as ligand-gated ion channels and function as such in the central and peripheral nervous systems. Recently, however, non-ionic signaling mechanisms via nAChRs have been demonstr
Externí odkaz:
https://doaj.org/article/e3dca2c0dcc244888c3c7ab7f37cf7d2
Autor:
S. L. Moore, C. J. Ciccarino, D. Halbertal, L. J. McGilly, N. R. Finney, K. Yao, Y. Shao, G. Ni, A. Sternbach, E. J. Telford, B. S. Kim, S. E. Rossi, K. Watanabe, T. Taniguchi, A. N. Pasupathy, C. R. Dean, J. Hone, P. J. Schuck, P. Narang, D. N. Basov
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-7 (2021)
Here, the authors investigate the lattice dynamics of twisted hexagonal boron nitride layers via nano-infrared spectroscopy, showing local and stacking-dependent variations of the optical phonon frequencies associated to the interaction with the grap
Externí odkaz:
https://doaj.org/article/3f943d04735d4a2892ef37bf8c6462f1
Autor:
Arik J. Hone, J. Michael McIntosh
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
In the nervous system, nicotinic acetylcholine receptors (nAChRs) rapidly transduce a chemical signal into one that is electrical via ligand-gated ion flux through the central channel of the receptor. However, some nAChR subunits are expressed by non
Externí odkaz:
https://doaj.org/article/13e4de7b005b4f66b4ce7b2e24b69f0e
Autor:
R. C. Calizo, M. K. Bell, A. Ron, M. Hu, S. Bhattacharya, N. J. Wong, W. G. M. Janssen, G. Perumal, P. Pederson, S. Scarlata, J. Hone, E. U. Azeloglu, P. Rangamani, R. Iyengar
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-17 (2020)
Abstract The shape of the cell is connected to its function; however, we do not fully understand underlying mechanisms by which global shape regulates a cell’s functional capabilities. Using theory, experiments and simulation, we investigated how p
Externí odkaz:
https://doaj.org/article/eb7c10f749f0463c9031a99f52469a1b
Autor:
B. M. Hunt, J. I. A. Li, A. A. Zibrov, L. Wang, T. Taniguchi, K. Watanabe, J. Hone, C. R. Dean, M. Zaletel, R. C. Ashoori, A. F. Young
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-7 (2017)
The phase diagram of bilayer graphene at high magnetic fields has been an outstanding question, with orders possibly between multiple internal quantum degrees of freedom. Here, Hunt et al. report the measurement of the valley and orbital order, allow
Externí odkaz:
https://doaj.org/article/1e1523775c724786a9a542500377d2bd
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2019)
Venomous marine snails of the genus Conus employ small peptides to capture prey, mainly osteichthyes, mollusks, and worms. A subset of these peptides known as α-conotoxins, are antagonists of nicotinic acetylcholine receptors (nAChRs). These disulfi
Externí odkaz:
https://doaj.org/article/acaa18b7a98842d48a49f19bcd73c9b2
Akademický článek
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Akademický článek
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Autor:
Katrin Richter, Sabrina Sagawe, Andreas Hecker, Mira Küllmar, Ingolf Askevold, Jelena Damm, Sarah Heldmann, Michael Pöhlmann, Sophie Ruhrmann, Michael Sander, Klaus-Dieter Schlüter, Sigrid Wilker, Inke R. König, Wolfgang Kummer, Winfried Padberg, Arik J. Hone, J. Michael McIntosh, Anna Teresa Zakrzewicz, Christian Koch, Veronika Grau
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Blood levels of the acute phase reactant C-reactive protein (CRP) are frequently measured as a clinical marker for inflammation, but the biological functions of CRP are still controversial. CRP is a phosphocholine (PC)-binding pentraxin, mainly produ
Externí odkaz:
https://doaj.org/article/5e2707b530894516b8c0f1772f70b0da