Zobrazeno 1 - 10
of 78
pro vyhledávání: '"J, Holroyde"'
Autor:
Peter R. Kowey, Paul Dorian, Craig M. Pratt, Stefan H. Hohnloser, Jose Brum, Preston Dunnmon, Hussein R. Al-Khalidi, Michael J. Holroyde
Publikováno v:
Journal of the American College of Cardiology. 52(13):1076-1083
ObjectivesThe goal of this study was to determine whether azimilide, as compared with placebo, will reduce the number of emergency department (ED) visits and hospitalizations caused by arrhythmias or cardiac events in patients with an implantable car
Autor:
Igor Singer, Michael J. Holroyde, Craig M. Pratt, Jose Brum, Paul Dorian, Martin Borggrefe, Michael van der Laan, Daljit S. Tatla, David S. Cannom, Johannes Brachmann, Robert J. Myerburg, Hussein R. Al-Khalidi, Stefan H. Hohnloser
Publikováno v:
Circulation. 110:3646-3654
Background— Although implanted cardioverter defibrillators (ICDs) effectively treat sustained ventricular tachyarrhythmias, up to 50% of ICD recipients eventually require concomitant antiarrhythmic drug therapy to prevent symptomatic arrhythmia rec
Autor:
Peter J. Schwartz, Steven N. Singh, Craig M. Pratt, A. John Camm, Stephen R. Marcello, Alive Investigators, Michael J. Holroyde, Hussein R. Al-Khalidi, Jose Brum
Publikováno v:
Journal of the American College of Cardiology. 43:1211-1216
Objectives The purpose of this study was to assess the effect of oral azimilide dihydrochloride (AZ) 100 mg versus placebo on the onset, termination, and prevalence of atrial fibrillation (AF) in a subpopulation of patients in the Azimilide Postinfar
Autor:
Peter J. Schwartz, A. John Camm, Jose Brum, Hussein R. Al-Khalidi, Edmund H. Sonnenblick, Roger Karam, Michael J. Holroyde, Craig M. Pratt, Maria J. Spyt
Publikováno v:
Circulation. 109:990-996
Background— Depressed left ventricular function (LVF) and low heart rate variability (HRV) identify patients at risk of increased mortality after myocardial infarction (MI). Azimilide, a novel class III antiarrhythmic drug, was investigated for its
Autor:
Martin Borggrefe, Jose Brum, Robert J. Myerburg, Michael van der Laan, Paul Dorian, Daljit S. Tatla, Stefan H. Hohnloser, Johannes Brachmann, Michael J. Holroyde, David S. Cannom, Craig M. Pratt, Hussein R. Al-Khalidi
Publikováno v:
The American Journal of Cardiology. 95:274-276
This report presents the rationale and study design details of the SHock Inhibition Evaluation with Azimilide study, which is recruiting 624 patients with implantable cardioverter-defibrillators (ICDs) who are at risk for life-threatening ventricular
Autor:
Stephen R. Marcello, Peter J. Schwartz, Jose Brum, Martin Borggrefe, Paul Dorian, Michael J. Holroyde, Hussein R. Al-Khalidi, A. John Camm, Craig M. Pratt
Publikováno v:
Journal of the American College of Cardiology. 48(3)
Objectives The purpose of this study was to assess the incidence, temporal characteristics, and risk factors associated with azimilide-associated torsades de pointes (TdP) ventricular tachycardia. Background Azimilide dihydrochloride is a class III a
Autor:
Michael J. Holroyde, Hussein R. Al-Khalidi, Igor Singer, Patrick J. Tchou, Tony W. Simmons, Jose Brum, Imran Niazi, Richard Henthorn
Publikováno v:
Journal of the American College of Cardiology. 43(1)
OBJECTIVES This study evaluated the effects of azimilide dihydrochloride (AZ) on anti-tachycardia pacing (ATP) and shock-terminated events in patients with implantable cardioverter defibrillators (ICDs). BACKGROUND Animal studies have shown the effec
Autor:
Craig M, Pratt, Steven N, Singh, Hussein R, Al-Khalidi, Jose M, Brum, Michael J, Holroyde, Stephen R, Marcello, Peter J, Schwartz, A John, Camm
Publikováno v:
Journal of the American College of Cardiology. 43(7)
The purpose of this study was to assess the effect of oral azimilide dihydrochloride (AZ) 100 mg versus placebo on the onset, termination, and prevalence of atrial fibrillation (AF) in a subpopulation of patients in the Azimilide Postinfarct Survival
Publikováno v:
Journal of Biological Chemistry. 254:6478-6482
Porcine left ventricular cardiac myosin and rabbit white skeletal myosin were phosphorylated by rabbit skeletal myosin light chain kinase and their Ca2+ binding properties were examined by equilibrium dialysis techniques. No significant effect of pho