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Akademický článek

Dosing and treatment duration of suppressive antimicrobial therapy in orthopedic implant infections: a cohort study

Autor: J. L. J. Hanssen, R. J. P. van der Wal, H. M. J. van der Linden, J. van Prehn, H. Scheper, M. G. J. de Boer

Publikováno v: Journal of Bone and Joint Infection, Vol 9, Pp 149-159 (2024)

Introduction: Limited data inform about the optimal dosing and duration of suppressive antimicrobial therapy (SAT) for orthopedic implant infection (OII). We aimed to compare the effectiveness of low-dosage with standard-dosage SAT and evaluate the s

Externí odkaz: https://doaj.org/article/51a841cf153341e9bfecb2f4fe77f8dc

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Akademický článek

The shape of fringing tidal flats in engineered estuaries

Autor: Jill L. J. Hanssen, Bram C. van Prooijen, Dirk S. van Maren

Publikováno v: Frontiers in Marine Science, Vol 11 (2024)

For the management of estuaries and the preservation of tidal flats it is crucial to understand the tidal flat shape and development. Previous work focused predominantly on the quasi-equilibrium shape of tidal flats along open coasts with a dominant

Externí odkaz: https://doaj.org/article/9d3c13527f6c43329f96cd3b3017da78

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Akademický článek

Safe shortening of antibiotic treatment duration for complicated Staphylococcus aureus bacteraemia (SAFE trial): protocol for a randomised, controlled, open-label, non-inferiority trial comparing 4 and 6 weeks of antibiotic treatment

Publikováno v: BMJ Open, Vol 13, Iss 4 (2023)

Introduction A major knowledge gap in the treatment of complicated Staphylococcus aureus bacteraemia (SAB) is the optimal duration of antibiotic therapy. Safe shortening of antibiotic therapy has the potential to reduce adverse drug events, length of

Externí odkaz: https://doaj.org/article/cf2fa20a75a4412a9dbd8b21a6ce2c68

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Akademický článek

Convalescent Plasma in a Patient with Protracted COVID-19 and Secondary Hypogammaglobulinemia Due to Chronic Lymphocytic Leukemia: Buying Time to Develop Immunity?

Autor: Jaap L. J. Hanssen, Johan Stienstra, Stefan A. Boers, Cilia R. Pothast, Hans L. Zaaijer, Jennifer M. Tjon, Mirjam H. M. Heemskerk, Mariet C. W. Feltkamp, Sandra M. Arend

Publikováno v: Infectious Disease Reports, Vol 13, Iss 4, Pp 855-864 (2021)

It is not exactly clear yet which type of immune response prevails to accomplish viral clearance in coronavirus disease 2019 (COVID-19). Studying a patient with chronic lymphocytic leukemia and hypogammaglobulinemia who suffered from COVID-19 provide

Externí odkaz: https://doaj.org/article/4b6894beb1a743c696f98932552c06d5

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Akademický článek

Neutrophil Migratory Patterns: Implications for Cardiovascular Disease

Autor: Albert Dahdah, Jillian Johnson, Sreejit Gopalkrishna, Robert M. Jaggers, Darren Webb, Andrew J. Murphy, Nordin M. J. Hanssen, Beatriz Y. Hanaoka, Prabhakara R. Nagareddy

Publikováno v: Frontiers in Cell and Developmental Biology, Vol 10 (2022)

The body’s inflammatory response involves a series of processes that are necessary for the immune system to mitigate threats from invading pathogens. Leukocyte migration is a crucial process in both homeostatic and inflammatory states. The mechanis

Externí odkaz: https://doaj.org/article/e26894bfcf9742c38e24a1a5e8b660f4

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Akademický článek

Mid-Liver Stage Arrest of Plasmodium falciparum Schizonts in Primary Porcine Hepatocytes

Autor: Saskia C. van der Boor, Geert-Jan van Gemert, Alex E. J. Hanssen, Youri M. van Waardenburg, Matthew B. B. McCall, Teun Bousema, Johannes H. W. de Wilt, Robert W. Sauerwein, Annie S. P. Yang

Publikováno v: Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)

During co-evolution Plasmodium parasites and vertebrates went through a process of selection resulting in defined and preferred parasite-host combinations. As such, Plasmodium falciparum (Pf) sporozoites can infect human hepatocytes while seemingly i

Externí odkaz: https://doaj.org/article/2644ab98dc5840d8b949a59a42cc495a

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Pyridoxamine reduces methylglyoxal and markers of glycation and endothelial dysfunction, but does not improve insulin sensitivity or vascular function in abdominally obese individuals: A randomized double-blind placebo-controlled trial

Autor: Mathias D. G. Van den Eynde, Alfons J. H. M. Houben, Jean L. J. M. Scheijen, Armand M. A. Linkens, Petra M. Niessen, Nynke Simons, Nordin M. J. Hanssen, Yvo H. A. M. Kusters, Simone J. M. P. Eussen, Toshio Miyata, Coen D. A. Stehouwer, Casper G. Schalkwijk

Publikováno v: Diabetes, Obesity and Metabolism, 25(5), 1280-1291. Wiley-Blackwell
Diabetes Obesity & Metabolism. Wiley

Aim: To investigate the effects of pyridoxamine (PM), a B6 vitamer and dicarbonyl scavenger, on glycation and a large panel of metabolic and vascular measurements in a randomized double-blind placebo-controlled trial in abdominally obese individuals.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3452d24d9a3484faf2bf49335549572
https://doi.org/10.1111/dom.14977

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Akademický článek

Postprandial Glucose Spikes, an Important Contributor to Cardiovascular Disease in Diabetes?

Autor: Nordin M. J. Hanssen, Michael J. Kraakman, Michelle C. Flynn, Prabhakara R. Nagareddy, Casper G. Schalkwijk, Andrew J. Murphy

Publikováno v: Frontiers in Cardiovascular Medicine, Vol 7 (2020)

Clinical trials investigating whether glucose lowering treatment reduces the risk of CVD in diabetes have thus far yielded mixed results. However, this doesn't rule out the possibility of hyperglycemia playing a major causal role in promoting CVD or

Externí odkaz: https://doaj.org/article/fe46a04627e34faf993da5147bd48de5

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Akademický článek

Polymorphisms in Glyoxalase I Gene Are Not Associated with Glyoxalase I Expression in Whole Blood or Markers of Methylglyoxal Stress: The CODAM Study

Autor: Kim Maasen, Nordin M. J. Hanssen, Carla J. H. van der Kallen, Coen D. A. Stehouwer, Marleen M. J. van Greevenbroek, Casper G. Schalkwijk

Publikováno v: Antioxidants, Vol 10, Iss 2, p 219 (2021)

Glyoxalase 1 (Glo1) is the rate-limiting enzyme in the detoxification of methylglyoxal (MGO) into D-lactate. MGO is a major precursor of advanced glycation endproducts (AGEs), and both are associated with development of age-related diseases. Since ge

Externí odkaz: https://doaj.org/article/15093e4bf4954021ad27ace7b77c102f

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A known unknown? Pharmacological prevention of venous thromboembolism in nursing home residents

Autor: Steffie H. A. Brouns, Jos M. G. A. Schols, Arina J. ten Cate-Hoek, Hugo ten Cate, Bart Spaetgens, Renée A. G. Brüggemann, Teba Alnima, Nordin M J Hanssen

Publikováno v: Journal of the American Geriatrics Society, 69, 3338-3343
Journal of the American Geriatrics Society, 69, 11, pp. 3338-3343
Journal of the American Geriatrics Society, 69(11), 3338-3343. Wiley-Blackwell
Journal of the American Geriatrics Society, 69(11), 3338-3343. Wiley

Contains fulltext : 245942.pdf (Publisher’s version ) (Open Access)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::487a2998c071f15f4dbba812dfacce7a
https://doi.org/10.1111/jgs.17422

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