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of 631
pro vyhledávání: '"J, Hadgraft"'
This work expands the recently developed compartmental model for skin transport to model variable diffusion and/or partition coefficients, and the presence of slow equilibration/slow binding kinetics within stratum corneum. The model was validated by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a52b63acb94d031b788b1b4481936e8
https://hdl.handle.net/11541.2/30922
https://hdl.handle.net/11541.2/30922
Publikováno v:
International Journal of Pharmaceutics. 269:323-328
The purpose of the present study was to compare Franz cells (FC) and microdialysis (MD) for monitoring the skin absorption of salicylic acid (SA). The influence of pH on SA flux was also assessed by these two techniques. Excised abdominal human skin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eddecf019c185ab2cfaeb61bc39d7e32
https://doi.org/10.1016/j.ijpharm.2003.09.012
https://doi.org/10.1016/j.ijpharm.2003.09.012
Publikováno v:
Journal of Physics D: Applied Physics. 36:364-368
We report the first use of GARField (STRAFI-like) magnetic resonance profiling (1D-MRI) to study skin hydration, both in vitro and in vivo. It is shown that, for in vitro samples, a high degree of reproducibility is achievable for skin samples from a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8446a820d45881ce8049b565eaab36ce
https://doi.org/10.1088/0022-3727/36/4/306
https://doi.org/10.1088/0022-3727/36/4/306
Akademický článek
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Akademický článek
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Publikováno v:
Pharmaceutical research. 2(5)
The distribution behavior of salicylic acid and its various esters (methyl, ethyl, phenyl, and glycol) between different semisolid vehicles (PEG, Carbopol 940, Plastibase) and non-miscible second phases has been examined over a range of temperature.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1897bdef891df9a2b1bcb36a7f0f8ba0
https://pubmed.ncbi.nlm.nih.gov/24272841
https://pubmed.ncbi.nlm.nih.gov/24272841
Publikováno v:
Pharmaceutical research. 3(5)
The release characteristics of aqueous and oily creams (BP) containing urea up to concentrations of 10% have been studied. The results show that the urea has little influence on the ability of the formulation to release its active ingredient, in this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3fb3562923bbadbdef9ef957b53d7124
https://pubmed.ncbi.nlm.nih.gov/24271713
https://pubmed.ncbi.nlm.nih.gov/24271713
Publikováno v:
Pharmaceutical research. 3(4)
Gel formulations are often used in topical drug delivery, and the drug release is controlled by two factors, the thermodynamic activity of the drug and the microviscosity of the gel. The latter property has been probed by observing the dynamic light
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::27e79ca8f1d261ae359a5a497c28ebe7
https://pubmed.ncbi.nlm.nih.gov/24271584
https://pubmed.ncbi.nlm.nih.gov/24271584
Publikováno v:
The British journal of dermatology. 164(6)
Aqueous Cream BP is frequently prescribed for patients with eczema and is known to induce sensitivity in certain patients and also to decrease the thickness of the stratum corneum (SC). We have previously reported methodology to quantify corneocyte m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a178603efcfbe7968f86fbf0d6db82b8
https://pubmed.ncbi.nlm.nih.gov/21615367
https://pubmed.ncbi.nlm.nih.gov/21615367
Publikováno v:
The British journal of dermatology. 164(5)
The barrier function of the skin may be characterized by a number of biophysical and molecular methods. Variation in the barrier properties as a function of depth has not been explored in detail.To characterize changes in corneocyte surface area, cor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c7c74e5bad0eab1cb07fd40b7474eb83
https://pubmed.ncbi.nlm.nih.gov/21219288
https://pubmed.ncbi.nlm.nih.gov/21219288