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Akademický článek
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Autor:
G. J. Brakenhoff, Emile A. Hendriks, Marcel J. T. Reinders, R. M. Heethaar, P. J. H. Bronkorsta, J. Grimbergen
Publikováno v:
Pattern Recognition Letters. 21:413-424
For the purpose of automating a clinical diagnostic apparatus to quantify the deformability of human red blood cells, we present an automated image analysis procedure for on-line detection of the cell shape based upon the method of parametric deforma
Autor:
J. Grimbergen, Evert-Jan Nijhof, Jan J. Sixma, P.J.H. Bronkhorst, G.J. Brakenhoff, G.J. Streekstra
Publikováno v:
Biophysical Journal, 69, 1666-1673. Biophysical Society
Biophysical journal, 69(5), 1666-1673. Biophysical Society
Biophysical journal, 69(5), 1666-1673. Biophysical Society
In this new method for studying the shape recovery of deformed red blood cells, three optical traps ("optical tweezers") induce a parachute-shaped red cell deformation, which is comparable to the deformation in small capillaries. The shape recovery i
Publikováno v:
Blood Coagulation & Fibrinolysis. 4:679-687
Publikováno v:
British journal of haematology. 96(2)
We used multiple optical trapping to study the mechanism of red cell (dis)aggregation. Two sets of optical 'tweezers' were used to bring two red blood cells together to form a two-cell aggregate and then to pull them apart, to study the interaction b
Publikováno v:
Blood. 84(9)
The plasminogen activator inhibitor PAI-1 is markedly elevated in vivo and in vitro upon exposure to the inflammatory mediators tumor necrosis factor alpha (TNF alpha), interleukin-1 (IL-1), and bacterial lipopolysaccharide. Here we report that the i
Publikováno v:
Blood coagulationfibrinolysis : an international journal in haemostasis and thrombosis. 4(5)
The aim of this study was to investigate the interactions of t-PA and plasminogen with fibrin derived from an abnormal fibrinogen detected in a 40-year-old male patient who had had an episode of thrombophlebitis with pulmonary embolism. An abnormal f
Publikováno v:
Blood. 80(8)
In the A alpha-chain gene coding for an abnormal fibrinogen (fibrinogen Marburg) we identified a single base substitution (A--T) that changes the codon A alpha 461 AAA (Lys) to TAA (Stop). The propositus was found to be homozygous for the mutation, w
Publikováno v:
Biorheology. 32:254-254