Preclinical evaluation of a candidate naked plasmid DNA vaccine against SARS-CoV-2

Autor: Ria Lassaunière, Charlotta Polacek, Gregers J. Gram, Anders Frische, Jeanette Linnea Tingstedt, Maren Krüger, Brigitte G. Dorner, Anthony Cook, Renita Brown, Tatyana Orekov, Tammy Putmon-Taylor, Tracey-Ann Campbell, Jack Greenhouse, Laurent Pessaint, Hanne Andersen, Mark G. Lewis, Anders Fomsgaard

Publikováno v: npj Vaccines, Vol 6, Iss 1, Pp 1-13 (2021)

Abstract New generation plasmid DNA vaccines may be a safe, fast and simple emergency vaccine platform for preparedness against emerging viral pathogens. Applying platform optimization strategies, we tested the pre-clinical immunogenicity and protect

Externí odkaz: https://doaj.org/article/eb1cc7b9d0d241ab959968f66a8f49b5

The continuous reaction time test for minimal hepatic encephalopathy validated by a randomized controlled multi-modal intervention-A pilot study.

Autor: M M Lauridsen, S Mikkelsen, T Svensson, J Holm, C Klüver, J Gram, H Vilstrup, O B Schaffalitzky de Muckadell

Publikováno v: PLoS ONE, Vol 12, Iss 10, p e0185412 (2017)

Minimal hepatic encephalopathy (MHE) is clinically undetectable and the diagnosis requires psychometric tests. However, a lack of clarity exists as to whether the tests are in fact able to detect changes in cognition.To examine if the continuous reac

Externí odkaz: https://doaj.org/article/db8929798f1c45fe8ac6e02ba114ec62

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The combined effect of Parathyroid hormone (1-34) and whole-body Vibration exercise in the treatment of postmenopausal OSteoporosis (PaVOS study):a randomized controlled trial

Autor: Jesper Ryg, J Gram, Niklas Rye Jørgensen, Stinus Hansen, Tahir Masud, Ditte Beck Jepsen

Publikováno v: Jepsen, D B, Ryg, J, Hansen, S, Jørgensen, N R, Gram, J & Masud, T 2019, ' The combined effect of Parathyroid hormone (1-34) and whole-body Vibration exercise in the treatment of postmenopausal OSteoporosis (PaVOS study) : a randomized controlled trial ', Osteoporosis International, vol. 30, no. 9, pp. 1827-1836 . https://doi.org/10.1007/s00198-019-05029-z
Osteoporosis International
Jepsen, D B, Ryg, J, Hansen, S, Jørgensen, N R, Gram, J & Masud, T 2019, ' The combined effect of Parathyroid hormone (1-34) and whole-body Vibration exercise in the treatment of postmenopausal OSteoporosis (PaVOS study) : a randomized controlled trial ', Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, vol. 30, no. 9, pp. 1827-1836 . https://doi.org/10.1007/s00198-019-05029-z

Summary Treatment effects of combining teriparatide and whole-body vibration exercise (WBV) vs teriparatide alone in twelve months were compared using bone mineral density (BMD), bone microarchitecture, and bone turnover markers. We found an increase

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05b015cca100931cfe79a2d4f8c26620
https://findresearcher.sdu.dk:8443/ws/files/153547185/The_combined_effect_of_Parathyroid_hormone_1_34_and_whole_body_Vibration_exercise_in_the_treatment_of_postmenopausal_OSteoporosis_PaVOS_study_.pdf

Sex differences in coronary plaque composition evaluated by coronary computed tomography angiography in newly diagnosed Type 2 diabetes:association with low-grade inflammation

Autor: M. Mrgan, J. Gram, M. Hecht Olsen, D. Dey, B. Linde Nørgaard, N. P. Rønnow Sand

Publikováno v: Mrgan, M, Gram, J, Hecht Olsen, M, Dey, D, Linde Nørgaard, B, Gram, J & Rønnow Sand, N P 2018, ' Sex differences in coronary plaque composition evaluated by coronary computed tomography angiography in newly diagnosed Type 2 diabetes : association with low-grade inflammation ', Diabetic Medicine, vol. 35, no. 11, pp. 1588-1595 . https://doi.org/10.1111/dme.13768
Mrgan, M, Gram, J, Hecht Olsen, M, Dey, D, Linde Nørgaard, B, Gram, J & Rønnow Sand, N P 2018, ' Sex differences in coronary plaque composition evaluated by coronary computed tomography angiography in newly diagnosed Type 2 diabetes : Association with low-grade inflammation ', Diabetic Medicine, vol. 35, no. 11, pp. 1588-1595 . https://doi.org/10.1111/dme.13768

Aim: To determine differences in coronary plaque composition and inflammatory biomarkers between men and women with newly diagnosed Type 2 diabetes without known cardiovascular disease. Methods: A total of 88 people with newly diagnosed (0.05). The m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bba36383d66a50cb8c8144073161308
https://pure.au.dk/portal/da/publications/sex-differences-in-coronary-plaque-composition-evaluated-by-coronary-computed-tomography-angiography-in-newly-diagnosed-type-2-diabetes(21fcc74e-1d74-41c6-9ad3-3ed236954d20).html