Zobrazeno 1 - 10
of 186
pro vyhledávání: '"J, Godbillon"'
Publikováno v:
Biopharmaceutics & Drug Disposition. 19:237-244
Twelve young (mean age 23 years, range 18–28) and 12 elderly (mean age 76 years, range 65–89) volunteers were given a single oral dose of 80 mg valsartan after an overnight fast. Each group consisted of six male and six female subjects. Mean syst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f3bc94531b79926aa9fdba9294ceb26e
https://doi.org/10.1002/(sici)1099-081x(199805)19:4<237::aid-bdd100>3.0.co
https://doi.org/10.1002/(sici)1099-081x(199805)19:4<237::aid-bdd100>3.0.co
Publikováno v:
Biopharmaceutics & Drug Disposition. 19:259-262
The effect of food on the pharmacokinetics of the antiepileptic rufinamide was investigated in healthy volunteers. Twelve subjects were treated with single pre-oral doses of 600 mg of rufinamide after overnight fasting or a fat and protein rich break
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::635e09aaaccfdad6dbcdaf3f735a4ff8
https://doi.org/10.1002/(sici)1099-081x(199805)19:4<259::aid-bdd98>3.0.co
https://doi.org/10.1002/(sici)1099-081x(199805)19:4<259::aid-bdd98>3.0.co
Autor:
H. Howald, F. Marfil, J. M. Cardot, Antoine Sioufi, N. Gauducheau, F. Vreeland, V. Pineau, J. Godbillon, C. Czendlik, Ch. Pfister, A. Jaouen
Publikováno v:
Biopharmaceutics & Drug Disposition. 18:779-789
Letrozole is a new non-steroidal inhibitor of the aromatase enzyme system. It is currently under development for the treatment of postmenopausal women with advanced breast cancer. Absolute bioavailability of letrozole when given orally as one 2.5 mg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f6afe1b37ed233501529ab3a39555cab
https://doi.org/10.1002/(sici)1099-081x(199712)18:9<779::aid-bdd64>3.0.co
https://doi.org/10.1002/(sici)1099-081x(199712)18:9<779::aid-bdd64>3.0.co
Publikováno v:
Journal of Chromatography B: Biomedical Sciences and Applications. 703:147-158
An analytical method for the simultaneous determination of imipramine (IMI) and its N-desmethyl metabolite, desipramine (DIMI) in human plasma by capillary gas chromatography-mass selective detection (GC-MS), with D4-imipramine (D4-IMI) and D4-desipr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66100b71728e9d13281f8fe5f3f9cb48
https://doi.org/10.1016/s0378-4347(97)00400-3
https://doi.org/10.1016/s0378-4347(97)00400-3
Autor:
F. Ezzet, P. Trunet, J. Godbillon, H. Howald, Antoine Sioufi, N. Sandrenan, C. Czendlik, Ch. Pfister
Publikováno v:
Biopharmaceutics & Drug Disposition. 18:489-497
Letrozole is a new non-steroidal inhibitor of the aromatase enzyme system. It is currently under development for the treatment of postmenopausal women with advanced breast cancer. To investigate the influence of food on the bioavailability of letrozo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a0f649ec1a30b47eef2b731efb97b6a9
https://doi.org/10.1002/(sici)1099-081x(199708)18:6<489::aid-bdd36>3.0.co
https://doi.org/10.1002/(sici)1099-081x(199708)18:6<489::aid-bdd36>3.0.co
Publikováno v:
Journal of Chromatography B: Biomedical Sciences and Applications. 691:145-153
An analytical method for the determination of artemether (A) and its metabolite dihydroartemisinin (DHA) in human plasma has been developed and validated. The method is based on high-performance liquid chromatography (HPLC) and electrochemical detect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e386547ba586341239a8c21cc7f32367
https://doi.org/10.1016/s0378-4347(96)00431-8
https://doi.org/10.1016/s0378-4347(96)00431-8
Publikováno v:
European Journal of Pharmaceutical Sciences. 4:139-145
The binding of the prodrug benazepril and its active metabolite benazeprilat to human serum albumin (HSA) and to human serum proteins was studied in vitro by equilibrium dialysis using 14 C-labelled compounds. The extent of binding to serum proteins
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::312763a4993089da318a3506e67cba80
https://doi.org/10.1016/0928-0987(95)00041-0
https://doi.org/10.1016/0928-0987(95)00041-0
Publikováno v:
Journal of Chromatography B: Biomedical Sciences and Applications. 678:354-359
A method for the simultaneous determination of isosorbide dinitrate (ISDN) and its mononitrate metabolites (2- and 5-ISMN) in human plasma by capillary gas chromatography with electron-capture detection was developed. Two internal standards were used
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eda6cc1657804d5883d90af0479682b1
https://doi.org/10.1016/0378-4347(95)00570-6
https://doi.org/10.1016/0378-4347(95)00570-6
Publikováno v:
Journal of Immunoassay. 17:29-46
An original solid phase method for direct radioimmunoassay of the antipsychotic savoxepine (CGP 19,486 A) in plasma has been developed which does not require the extraction of the parent drug with organic solvents. The assay showed good reproducibili
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1145a9cfa8bed598109b2a8c38e8ba56
https://doi.org/10.1080/01971529608005777
https://doi.org/10.1080/01971529608005777
Publikováno v:
Journal of Chromatography B: Biomedical Sciences and Applications. 667:307-313
Automated procedures for the determination of CGP 33,101 in plasma and the simultaneous determination of CGP 33,101 and its carboxylic acid metabolite, CGP 47,292, in urine are described. Plasma was diluted with water and urine with a pH 2 buffer pri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e7541d5cfba51e134fb61c97b11ce31
https://doi.org/10.1016/0378-4347(95)00026-f
https://doi.org/10.1016/0378-4347(95)00026-f