Zobrazeno 1 - 10
of 657
pro vyhledávání: '"J, Garvin"'
Autor:
Hannah L. Mackay, Helen R. Stone, George E. Ronson, Katherine Ellis, Alexander Lanz, Yara Aghabi, Alexandra K. Walker, Katarzyna Starowicz, Alexander J. Garvin, Patrick Van Eijk, Stefan A. Koestler, Elizabeth J. Anthony, Ann Liza Piberger, Anoop S. Chauhan, Poppy Conway-Thomas, Alina Vaitsiankova, Sobana Vijayendran, James F. Beesley, Eva Petermann, Eric J. Brown, Ruth M. Densham, Simon H. Reed, Felix Dobbs, Marco Saponaro, Joanna R. Morris
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Mammalian DNA replication relies on various DNA helicase and nuclease activities to ensure accurate genetic duplication, but how different helicase and nuclease activities are properly directed remains unclear. Here, we identify the ubiquiti
Externí odkaz:
https://doaj.org/article/28ce5cbc0af0403c82bcaf2f474d55ce
Autor:
George E. Ronson, Katarzyna Starowicz, Elizabeth J. Anthony, Ann Liza Piberger, Lucy C. Clarke, Alexander J. Garvin, Andrew D. Beggs, Celina M. Whalley, Matthew J. Edmonds, James F. J. Beesley, Joanna R. Morris
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract A synthetic lethal relationship exists between disruption of polymerase theta (Polθ), and loss of either 53BP1 or homologous recombination (HR) proteins, including BRCA1; however, the mechanistic basis of these observations are unclear. Her
Externí odkaz:
https://doaj.org/article/9fe50622466f46da85132eed80fe32f1
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-16 (2022)
Abstract Monoclonal antibodies (MAb) to members of the Small Ubiquitin-like modifier (SUMO) family are essential tools in the study of cellular SUMOylation. However, many anti-SUMO MAbs are poorly validated, and antibody matching to detection format
Externí odkaz:
https://doaj.org/article/d494bb1fca2344f7b3ce0e21e3ff61c2
Autor:
M. Golombek, N. H. Warner, J. A. Grant, E. Hauber, V. Ansan, C. M. Weitz, N. Williams, C. Charalambous, S. A. Wilson, A. DeMott, M. Kopp, H. Lethcoe-Wilson, L. Berger, R. Hausmann, E. Marteau, C. Vrettos, A. Trussell, W. Folkner, S. Le Maistre, N. Mueller, M. Grott, T. Spohn, S. Piqueux, E. Millour, F. Forget, I. Daubar, N. Murdoch, P. Lognonné, C. Perrin, S. Rodriguez, W. T. Pike, T. Parker, J. Maki, H. Abarca, R. Deen, J. Hall, P. Andres, N. Ruoff, F. Calef, S. Smrekar, M. M. Baker, M. Banks, A. Spiga, D. Banfield, J. Garvin, C. E. Newman, W. B. Banerdt
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
The InSight spacecraft landed on Mars on November 2018. Here, the authors characterize the surficial geology of the landing site and compare with observations and models derived from remote sensing data prior to landing and from ongoing in situ geoph
Externí odkaz:
https://doaj.org/article/4ddb238f4e9a41b193efa61d62e46113
Autor:
Timothy L. Miao, Shubreet Randhawa, Michael J. Roth, Yves Bureau, Joanne Howey, Gregory J. Garvin
Publikováno v:
Canadian Association of Radiologists Journal. 73:647-654
Purpose: The purpose is to demonstrate the existence of the parallel line sign (PLS), a dark line parallel to the sacroiliac joint (SIJ), and determine its prevalence, characteristics, and associations. Methods: 200 consecutive SIJ MRIs referred by r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21a20a75539afdbd38ba1e8ff57b9603
https://doi.org/10.1177/08465371211069493
https://doi.org/10.1177/08465371211069493
Publikováno v:
Journal of Construction Engineering and Management. 148
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f609aed539a3abb08579dd6b787a9e1f
https://doi.org/10.1061/(asce)co.1943-7862.0002405
https://doi.org/10.1061/(asce)co.1943-7862.0002405
Publikováno v:
In Medical Image Analysis January 2013 17(1):43-61
Autor:
Carter B. Casady, Michael J. Garvin
In North America, public-private partnerships (P3s) are increasingly using pre-development agreements to enhance collaboration between the public and private sectors. Known colloquially as “progressive P3s”, these agreements allow the private sec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af475b6f19ef00ce53053abf8ba875cc
https://hdl.handle.net/10919/112072
https://hdl.handle.net/10919/112072
The small ubiquitin-like modifier (SUMO) family is composed of five members, SUMO1, the highly similar SUMO2/SUMO3, SUMO4 and the tissue-specific SUMO5 (SUMO1P1). Sequence variation in SUMO4 is thought to prevent its maturation, resulting in an un-co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2c26234eb489f908f477fb63e6dc49bb
https://doi.org/10.1101/2022.03.23.485504
https://doi.org/10.1101/2022.03.23.485504
The E3 ubiquitin ligase RNF168 is a rate-limiting component of DNA double-strand break signalling that acts to amplify histone ubiquitylation. The confining of RNF168 chromatin spreading around DNA break sites has been related to constraining its exp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6f551f90a6d90d22d781050bd749b1de
https://doi.org/10.1101/2022.03.22.485326
https://doi.org/10.1101/2022.03.22.485326