Genome-wide association meta-analyses combining multiple risk phenotypes provide insights into the genetic architecture of cutaneous melanoma susceptibility

Autor: Landi, M.T. Bishop, D.T. MacGregor, S. Machiela, M.J. Stratigos, A.J. Ghiorzo, P. Brossard, M. Calista, D. Choi, J. Fargnoli, M.C. Zhang, T. Rodolfo, M. Trower, A.J. Menin, C. Martinez, J. Hadjisavvas, A. Song, L. Stefanaki, I. Scolyer, R. Yang, R. Goldstein, A.M. Potrony, M. Kypreou, K.P. Pastorino, L. Queirolo, P. Pellegrini, C. Cattaneo, L. Zawistowski, M. Gimenez-Xavier, P. Rodriguez, A. Elefanti, L. Manoukian, S. Rivoltini, L. Smith, B.H. Loizidou, M.A. Del Regno, L. Massi, D. Mandala, M. Khosrotehrani, K. Akslen, L.A. Amos, C.I. Andresen, P.A. Avril, M.-F. Azizi, E. Soyer, H.P. Bataille, V. Dalmasso, B. Bowdler, L.M. Burdon, K.P. Chen, W.V. Codd, V. Craig, J.E. Dębniak, T. Falchi, M. Fang, S. Friedman, E. Simi, S. Galan, P. Garcia-Casado, Z. Gillanders, E.M. Gordon, S. Green, A. Gruis, N.A. Hansson, J. Harland, M. Harris, J. Helsing, P. Henders, A. Hočevar, M. Höiom, V. Hunter, D. Ingvar, C. Kumar, R. Lang, J. Lathrop, G.M. Lee, J.E. Li, X. Lubiński, J. Mackie, R.M. Malt, M. Malvehy, J. McAloney, K. Mohamdi, H. Molven, A. Moses, E.K. Neale, R.E. Novaković, S. Nyholt, D.R. Olsson, H. Orr, N. Fritsche, L.G. Puig-Butille, J.A. Qureshi, A.A. Radford-Smith, G.L. Randerson-Moor, J. Requena, C. Rowe, C. Samani, N.J. Sanna, M. Schadendorf, D. Schulze, H.-J. Simms, L.A. Smithers, M. Song, F. Swerdlow, A.J. van der Stoep, N. Kukutsch, N.A. Visconti, A. Wallace, L. Ward, S.V. Wheeler, L. Sturm, R.A. Hutchinson, A. Jones, K. Malasky, M. Vogt, A. Zhou, W. Pooley, K.A. Elder, D.E. Han, J. Hicks, B. Hayward, N.K. Kanetsky, P.A. Brummett, C. Montgomery, G.W. Olsen, C.M. Hayward, C. Dunning, A.M. Martin, N.G. Evangelou, E. Mann, G.J. Long, G. Pharoah, P.D.P. Easton, D.F. Barrett, J.H. Cust, A.E. Abecasis, G. Duffy, D.L. Whiteman, D.C. Gogas, H. De Nicolo, A. Tucker, M.A. Newton-Bishop, J.A. Peris, K. Chanock, S.J. Demenais, F. Brown, K.M. Puig, S. Nagore, E. Shi, J. Iles, M.M. Law, M.H. GenoMEL Consortium Q-MEGA QTWIN Investigators ATHENS Melanoma Study Group 23andMe The SDH Study Group IBD Investigators Essen-Heidelberg Investigators AMFS Investigators MelaNostrum Consortium

Most genetic susceptibility to cutaneous melanoma remains to be discovered. Meta-analysis genome-wide association study (GWAS) of 36,760 cases of melanoma (67% newly genotyped) and 375,188 controls identified 54 significant (P < 5 × 10−8) loci wit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2127::f9497572df9165ff7b18fe8fd7541be8
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3077491

Transcriptome-Wide Association Study Reveals New Molecular Interactions Associated with Melanoma Pathogenesis.

Autor: Saad, Mohamed N.^1,2 (AUTHOR) m.n.saad@minia.edu.eg, Hamed, Mohamed^2,3 (AUTHOR)

Publikováno v: Cancers. Jul2024, Vol. 16 Issue 14, p2517. 20p.

Optimization of an optically implemented on-board FDMA demultiplexer

Autor: L.P. Riddle, J. Fargnoli

Publikováno v: MILCOM 91 - Conference record.

Performance of a 30-GHz frequency division multiple access (FDMA) uplink to a processing satellite is modeled for the case where the onboard demultiplexer is implemented optically. Included in the performance model are the effects of adjacent channel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8372a0d5ee0f010b7879e276c5a490f6
https://doi.org/10.1109/milcom.1991.258337

Pattern Analysis of Benign and Malignant Atypical Melanocytic Skin Lesions of Palms and Soles: Variations of Dermoscopic Features According to Anatomic Site and Personal Experience.

Autor: Tognetti, Linda¹ (AUTHOR) linda.tognetti@dbm.unisi.it, Cartocci, Alessandra^1,2 (AUTHOR), Moscarella, Elvira³ (AUTHOR), Lallas, Aimilios⁴ (AUTHOR), Dika, Emi^5,6 (AUTHOR), Fargnoli, Maria Concetta⁷ (AUTHOR), Longo, Caterina^8,9 (AUTHOR), Nazzaro, Gianluca¹⁰ (AUTHOR), Paoli, John^11,12 (AUTHOR), Stanganelli, Ignazio^13,14 (AUTHOR), Magi, Serena¹³ (AUTHOR), Lacarrubba, Francesco¹⁵ (AUTHOR), Broganelli, Paolo¹⁶ (AUTHOR), Perrot, Jean-Luc^17,18 (AUTHOR), Suppa, Mariano^18,19,20 (AUTHOR), Giuffrida, Roberta²¹ (AUTHOR), Cinotti, Elisa^1,20 (AUTHOR), Sofia, Lo Conte¹ (AUTHOR), Cataldo, Gennaro² (AUTHOR), Cevenini, Gabriele² (AUTHOR)

Publikováno v: Life (2075-1729). Jun2024, Vol. 14 Issue 6, p659. 22p.

Temporal regulation of non-transmembrane protein tyrosine kinase enzyme activity following T cell antigen receptor engagement

Autor: A L, Burkhardt, B, Stealey, R B, Rowley, S, Mahajan, M, Prendergast, J, Fargnoli, J B, Bolen

Publikováno v: The Journal of biological chemistry. 269(38)

We evaluated in Jurkat T cells the time-dependent responses of Fyn, Lck, Syk, and Zap following antibody-mediated cross-linking of the T cell antigen receptor. Our results show that the protein kinase activities of Fyn and Lck were activated within s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::9a74a40d6d4817ddb6525c502c543d31
https://pubmed.ncbi.nlm.nih.gov/7522230