Zobrazeno 1 - 10
of 576
pro vyhledávání: '"J, Ellner"'
Autor:
Xutao Wang, Arthur VanValkenberg, Aubrey R. Odom, Jerrold J. Ellner, Natasha S. Hochberg, Padmini Salgame, Prasad Patil, W. Evan Johnson
Publikováno v:
BMC Infectious Diseases, Vol 24, Iss 1, Pp 1-10 (2024)
Abstract Background Blood-based transcriptional gene signatures for tuberculosis (TB) have been developed with potential use to diagnose disease. However, an unresolved issue is whether gene set enrichment analysis of the signature transcripts alone
Externí odkaz:
https://doaj.org/article/016e2585317f4a44a035704461460bb7
Autor:
Betânia M F Nogueira, Sonya Krishnan, Beatriz Barreto‐Duarte, Mariana Araújo‐Pereira, Artur T L Queiroz, Jerrold J Ellner, Padmini Salgame, Thomas J Scriba, Timothy R Sterling, Amita Gupta, Bruno B Andrade
Publikováno v:
EMBO Molecular Medicine, Vol 14, Iss 12, Pp 1-13 (2022)
Abstract Tuberculosis (TB) is a leading cause of morbidity and mortality from a single infectious agent, despite being preventable and curable. Early and accurate diagnosis of active TB is critical to both enhance patient care, improve patient outcom
Externí odkaz:
https://doaj.org/article/4fc2d5911d0b44a3ba60614366d13b73
Autor:
Arianne Lovey, Sheetal Verma, Vaishnavi Kaipilyawar, Rodrigo Ribeiro-Rodrigues, Seema Husain, Moises Palaci, Reynaldo Dietze, Shuyi Ma, Robert D. Morrison, David. R. Sherman, Jerrold J. Ellner, Padmini Salgame
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
Halting tuberculosis transmission is crucial to TB elimination. Here the authors implicate IL-1R dependent T cell priming as the underlying mechanism determining variability in transmission of Mycobacterium tuberculosis strains.
Externí odkaz:
https://doaj.org/article/b73d2023e76b4beaa7e6df4b700103b2
Autor:
Chelsie Cintron, Prakash Babu Narasimhan, Lindsey Locks, Senbagavalli Babu, Pranay Sinha, Nonika Rajkumari, Vaishnavi Kaipilyawar, Anurag Bhargava, Kimberly Maloomian, Padma Chandrasekaran, Sheetal Verma, Noyal Joseph, W. Evan Johnson, Christine Wanke, C. Robert Horsburgh, Jerrold J. Ellner, Sonali Sarkar, Padmini Salgame, Subitha Lakshminarayanan, Natasha S. Hochberg
Publikováno v:
BMC Infectious Diseases, Vol 21, Iss 1, Pp 1-12 (2021)
Abstract Background Comorbidities such as undernutrition and parasitic infections are widespread in India and other tuberculosis (TB)-endemic countries. This study examines how these conditions as well as food supplementation and parasite treatment m
Externí odkaz:
https://doaj.org/article/f4f6126a845947aa98c138a681c53586
Autor:
Arthur VanValkenburg, Vaishnavi Kaipilyawar, Sonali Sarkar, Subitha Lakshminarayanan, Chelsie Cintron, Senbagavalli Prakash Babu, Selby Knudsen, Noyal Mariya Joseph, C. Robert Horsburgh, Pranay Sinha, Jerrold J. Ellner, Prakash Babu Narasimhan, William Evan Johnson, Natasha S. Hochberg, Padmini Salgame
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/dca0180db4324a1a8653686c18b9adf8
Autor:
Arthur VanValkenburg, Vaishnavi Kaipilyawar, Sonali Sarkar, Subitha Lakshminarayanan, Chelsie Cintron, Senbagavalli Prakash Babu, Selby Knudsen, Noyal Mariya Joseph, C. Robert Horsburgh, Pranay Sinha, Jerrold J. Ellner, Prakash Babu Narasimhan, W. Evan Johnson, Natasha S. Hochberg, Padmini Salgame
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
BackgroundMost individuals exposed to Mycobacterium tuberculosis (Mtb) develop latent tuberculosis infection (LTBI) and remain at risk for progressing to active tuberculosis disease (TB). Malnutrition is an important risk factor driving progression f
Externí odkaz:
https://doaj.org/article/f8572297768743e09aeec320c88d1698
Autor:
Artur T. L. Queiroz, Mariana Araújo-Pereira, Beatriz Barreto-Duarte, Adriano Gomes-Silva, Allyson G. Costa, Alice M. S. Andrade, João Pedro Miguez-Pinto, Renata Spener-Gomes, Alexandra B. Souza, Aline Benjamin, Flavia Sant’Anna, Marina C. Figueiredo, Vidya Mave, Padmini Salgame, Jerrold J. Ellner, Timothy R. Sterling, Marcelo Cordeiro-dos-Santos, Bruno B. Andrade, Valeria C. Rolla
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
IntroductionTuberculosis (TB) is a common opportunistic infection among people living with HIV. Diagnostic tests such as culture, Xpert-MTB-RIF, and ULTRA have low sensitivity in paucibacillary TB disease; a blood biomarker could improve TB diagnosti
Externí odkaz:
https://doaj.org/article/95a5a603cbed4baf938e562844374704
Autor:
Roberto Colangeli, Aditi Gupta, Solange Alves Vinhas, Uma Deepthi Chippada Venkata, Soyeon Kim, Courtney Grady, Edward C. Jones-López, Patricia Soteropoulos, Moisés Palaci, Patrícia Marques-Rodrigues, Padmini Salgame, Jerrold J. Ellner, Reynaldo Dietze, David Alland
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
Here, Colangeli et al. use a human household contact cohort to measure the rate of mutation and evolution of Mycobacterium tuberculosis strains and find that long term latency is characterized by reduced mutation rates compared to latency in the firs
Externí odkaz:
https://doaj.org/article/c8190181e06b4d39af146506e44cad8c
Autor:
Ismaheel O. Lawal, Kgomotso M. G. Mokoala, Matsontso Mathebula, Ingrid Moagi, Gbenga O. Popoola, Nontando Moeketsi, Maphoshane Nchabeleng, Chris Hikuam, Jerrold J. Ellner, Mark Hatherill, Bernard P. Fourie, Mike M. Sathekge
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
Patients who complete a standard course of anti-tuberculous treatment (ATT) for pulmonary tuberculosis and are declared cured according to the current standard of care commonly have residual metabolic activity (RMA) in their lungs on fluorine-18 fluo
Externí odkaz:
https://doaj.org/article/486373ef1fdb4620815bf15a8070e7a0
Autor:
Kamlesh Bhatt, Madhuri Bhagavathula, Sheetal Verma, Graham S. Timmins, Vojo P. Deretic, Jerrold J. Ellner, Padmini Salgame
Publikováno v:
Disease Models & Mechanisms, Vol 14, Iss 10 (2021)
Tuberculosis (TB) treatment regimens are lengthy, causing non-adherence to treatment. Inadequate treatment can lead to relapse and the development of drug resistance TB. Furthermore, patients often exhibit residual lung damage even after cure, increa
Externí odkaz:
https://doaj.org/article/6d65048b44aa4deea31ae57be740ec92