Zobrazeno 1 - 10
of 184
pro vyhledávání: '"J, Ellenberger"'
Publikováno v:
Acta Horticulturae
Publikováno v:
AAPS PharmSciTech. 19:1933-1956
Due to the high number of poorly soluble drugs in the development pipeline, novel processes for delivery of these challenging molecules are increasingly in demand. One such emerging method is KinetiSol, which utilizes high shear to produce amorphous
Publikováno v:
AAPS PharmSciTech. 19:1957-1970
Vemurafenib is a poorly soluble, low permeability drug that has a demonstrated need for a solubility-enhanced formulation. However, conventional approaches for amorphous solid dispersion production are challenging due to the physiochemical properties
Autor:
J. Ellenberger, Rajamani Krishna
Publikováno v:
Chemie Ingenieur Technik, 89(10), 1360-1366. Wiley-VCH Verlag
Application of sinusoidal vibrations in the longitudinal direction causes a significant enhancement in the flow rate of shear-thinning carboxymethylcellulose and polyacrylamide solutions inside capillaries. Depending on the vibration frequency and am
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e0cdda4c4cf9b96dfc334fab55d0d99
https://dare.uva.nl/personal/pure/en/publications/flow-enhancement-of-shearthinning-liquids-in-capillaries-subjected-to-longitudinal-vibrations(73921c61-bc0a-492d-b502-20cce183714e).html
https://dare.uva.nl/personal/pure/en/publications/flow-enhancement-of-shearthinning-liquids-in-capillaries-subjected-to-longitudinal-vibrations(73921c61-bc0a-492d-b502-20cce183714e).html
Publikováno v:
AAPS PharmSciTech. 17:180-190
The KinetiSol® Dispersing (KSD) technology has enabled the investigation into the use of polyvinyl alcohol (PVAL) as a concentration enhancing polymer for amorphous solid dispersions. Our previous study revealed that the 88% hydrolyzed grade of PVAL
Publikováno v:
AAPS PharmSciTech. 19(5)
Ritonavir is an anti-viral compound that has also been employed extensively as a CYP3A4 and P-glycoprotein (Pgp) inhibitor to boost the pharmacokinetic performance of compounds that undergo first pass metabolism. For use in combination products, ther
Autor:
Justin M. Keen, Daniel J. Ellenberger, Dave A. Miller, James W. McGinity, Robert O. Williams, Chris Brough, Marshall Cisneros
Publikováno v:
Journal of Pharmacy and Pharmacology. 68:678-691
Objectives To evaluate the effect of ritonavir (RTV) co-administration on the bioavailability of an amorphous dispersion of acetyl-11-keto-beta-boswellic acid (AKBA) and to develop a pharmaceutically acceptable AKBA–RTV combination tablet. Methods
Autor:
J. Ellenberger, T. Menahem, Y. Natchetoi, B. Naveh, T. Odenwald, Dirk Riehle, B. Mikhailovski
Publikováno v:
IEEE Software. 26:52-58
This article describes our experiences using open source software development practices at SAP. SAP is a major software developer and leader in business applications. We've found that open source practices can complement traditional top-down software
Autor:
Rajamani Krishna, J. Ellenberger
Publikováno v:
The Canadian Journal of Chemical Engineering, 81, 655-659. Wiley-Blackwell
We show that application of low-frequency vibrations, in the 30 to 60 Hz range, to the liquid phase of an air-water-silica catalyst slurry bubble column causes significant enhancement of both gas holdup and volumetric mass transfer coefficient over a
Autor:
Rajamani Krishna, J. Ellenberger
Publikováno v:
Chemical Engineering Science, 62(24), 7548-7553. Elsevier
This experimental study reports the influence of low-frequency vibrations, in the range of 60–400 Hz, on the rise of single air bubbles and slugs injected into two columns (of diameters 0.014 and 0.05 m), filled with liquids of varying densities (i