Zobrazeno 1 - 10
of 2 609
pro vyhledávání: '"J, Dwyer"'
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Autoimmune diabetes is a disease characterized by the selective destruction of insulin-secreting β-cells of the endocrine pancreas by islet-reactive T cells. Autoimmune disease requires a complex interplay between host genetic factors and environmen
Externí odkaz:
https://doaj.org/article/a6f03dea34474ef285e6800f9d4ebe3d
Autor:
Andrea J. Dwyer, Aniruddha Rathod, Carli King, F. E. R. Vuik, Phuong Gallagher, Anjee Davis, Eric M. Lander, Jose Perea
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
Early onset colorectal cancer (EOCRC) emerged as the fourth foremost contributor to cancer-related mortality among both genders in the late 1990s. Presently, EOCRC (
Externí odkaz:
https://doaj.org/article/a8430b6f0997412482b5f4807b6e760d
Autor:
Jeffrey Y. K. Wong, Arunika I. Ekanayake, Serhii Kharchenko, Steven E. Kirberger, Ryan Qiu, Payam Kelich, Susmita Sarkar, Jiaqian Li, Kleinberg X. Fernandez, Edgar R. Alvizo-Paez, Jiayuan Miao, Shiva Kalhor-Monfared, J. Dwyer John, Hongsuk Kang, Hwanho Choi, John M. Nuss, John C. Vederas, Yu-Shan Lin, Matthew S. Macauley, Lela Vukovic, William C. K. Pomerantz, Ratmir Derda
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract Peptide-based therapeutics have gained attention as promising therapeutic modalities, however, their prevalent drawback is poor circulation half-life in vivo. In this paper, we report the selection of albumin-binding macrocyclic peptides fro
Externí odkaz:
https://doaj.org/article/70cf58a7e9004f0fbc1e0c30b3084ed6
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-8 (2023)
Abstract We have used the LOw-Frequency ARray (LOFAR) to search for the growing tip of an intra-cloud (IC) positive leader. Even with our most sensitive beamforming method, where we coherently add the signals of about 170 antenna pairs, we were not a
Externí odkaz:
https://doaj.org/article/9f63371d598344c39f907f76d0890810
Autor:
Liam J. Dwyer, Saumya Maheshwari, Emily Levy, Mark C. Poznansky, Michael J. Whalen, Ruxandra F. Sîrbulescu
Publikováno v:
Journal of Neuroinflammation, Vol 20, Iss 1, Pp 1-19 (2023)
Abstract Traumatic brain injury (TBI) remains a major cause of death and severe disability worldwide. We found previously that treatment with exogenous naïve B cells was associated with structural and functional neuroprotection after TBI. Here, we u
Externí odkaz:
https://doaj.org/article/e5397a7437654fecb3bcdfefe1cd6bca
252 The combination of ACT and INDUKINE therapy leads to improved antitumor immunity in solid tumors
Autor:
Kyriakos Economides, Kristin Morris, Andres Salmeron, Connor J Dwyer, Heather R Brodkin, Daniel J Hicklin, Cynthia Seidel-Dugan, William M Winston, Olivia G Donovan, Julie LePrevost
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/2f1f22f5f1b0489b8bac8a7f7313a641
Autor:
Justin A. Spanier, Vivian Fung, Christine M. Wardell, Mohannad H. Alkhatib, Yixin Chen, Linnea A. Swanson, Alexander J. Dwyer, Matthew E. Weno, Nubia Silva, Jason S. Mitchell, Paul C. Orban, Majid Mojibian, C. Bruce Verchere, Brian T. Fife, Megan K. Levings
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 18 (2023)
Adoptive immunotherapy with Tregs is a promising approach for preventing or treating type 1 diabetes. Islet antigen–specific Tregs have more potent therapeutic effects than polyclonal cells, but their low frequency is a barrier for clinical applica
Externí odkaz:
https://doaj.org/article/07b12edb27a645e0ba884c7c896ee39b
Publikováno v:
Neurobiology of Disease, Vol 180, Iss , Pp 106077- (2023)
Acute injury to the central nervous system (CNS) remains a complex and challenging clinical need. CNS injury initiates a dynamic neuroinflammatory response, mediated by both resident and infiltrating immune cells. Following the primary injury, dysreg
Externí odkaz:
https://doaj.org/article/8248a11e671e49ac9d0e6940160fcfef
Publikováno v:
Geophysical Research Letters, Vol 50, Iss 8, Pp n/a-n/a (2023)
Abstract We have used the LOw‐Frequency ARray (LOFAR) to image a few lightning flashes during a particularly severe thunderstorm. The images show an exceptional amount of VHF activity at altitudes above 10 km. Much of this is in the form of small
Externí odkaz:
https://doaj.org/article/48d24ec42aa24c83a6fc3519f1d5c9b4
Autor:
Jeffrey Y. K. Wong, Arunika I. Ekanayake, Serhii Kharchenko, Steven E. Kirberger, Ryan Qiu, Payam Kelich, Susmita Sarkar, Jiaqian Li, Kleinberg X. Fernandez, Edgar R. Alvizo-Paez, Jiayuan Miao, Shiva Kalhor-Monfared, J. Dwyer John, Hongsuk Kang, Hwanho Choi, John M. Nuss, John C. Vederas, Yu-Shan Lin, Matthew S. Macauley, Lela Vukovic, William C. K. Pomerantz, Ratmir Derda
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/71139748923945fe95b7a358e1ee3960