Zobrazeno 1 - 10
of 3 902
pro vyhledávání: '"J, Donnelly"'
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-11 (2024)
Abstract Alzheimer’s disease (AD) and more than twenty other dementias, termed tauopathies, are pathologically defined by insoluble aggregates of the microtubule-associated protein tau (MAPT). Although tau aggregation correlates with AD symptomolog
Externí odkaz:
https://doaj.org/article/63d6afaec5c74d609f4ee8baa1f19312
Autor:
Amy Lynd, Samuel Gonahasa, Sarah G. Staedke, Ambrose Oruni, Catherine Maiteki-Sebuguzi, Penelope A. Hancock, Erin Knight, Grant Dorsey, Jimmy Opigo, Adoke Yeka, Agaba Katureebe, Mary Kyohere, Janet Hemingway, Moses R. Kamya, Daniel McDermott, Eric R. Lucas, Martin J. Donnelly
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Pyrethroid bednets treated with the synergist piperonyl butoxide (PBO) offer the possibility of improved vector control in mosquito populations with metabolic resistance. In 2017–2019, we conducted a large-scale, cluster-randomised trial (
Externí odkaz:
https://doaj.org/article/bfc7826f3d024a8f813aed9eb41abdc3
Autor:
Jaffer Okiring, Samuel Gonahasa, Catherine Maiteki-Sebuguzi, Agaba Katureebe, Irene Bagala, Peter Mutungi, Simon P. Kigozi, Jane F. Namuganga, Joaniter I. Nankabirwa, Moses R. Kamya, Martin J. Donnelly, Thomas S. Churcher, Sarah G. Staedke, Ellie Sherrard-Smith
Publikováno v:
Malaria Journal, Vol 23, Iss 1, Pp 1-11 (2024)
Abstract Background Disruptions in malaria control due to COVID-19 mitigation measures were predicted to increase malaria morbidity and mortality in Africa substantially. In Uganda, long-lasting insecticidal nets (LLINs) are distributed nationwide ev
Externí odkaz:
https://doaj.org/article/d3636a4a662f45899ed5d3a1c2468cc6
Autor:
Jackline Kosgei, John E. Gimnig, Vincent Moshi, Seline Omondi, Daniel P. McDermott, Martin J. Donnelly, Collins Ouma, Bernard Abong’o, Eric Ochomo
Publikováno v:
Malaria Journal, Vol 23, Iss 1, Pp 1-12 (2024)
Abstract Background Vector surveillance is among the World Health Organization global vector control response (2017–2030) pillars. Human landing catches are a gold standard but difficult to implement and potentially expose collectors to malaria inf
Externí odkaz:
https://doaj.org/article/5f69cd07c896458a90ed7087f334d0b0
Autor:
Jessy D. Martinez, Lydia G. Wilson, William P. Brancaleone, Kathryn G. Peterson, Donald S. Popke, Valentina Caicedo Garzon, Roxanne E. Perez Tremble, Marcus J. Donnelly, Stephany L. Mendez Ortega, Daniel Torres, James J. Shaver, Sha Jiang, Zhongying Yang, Sara J. Aton
Publikováno v:
Cell Reports, Vol 43, Iss 6, Pp 114266- (2024)
Summary: Fragile X syndrome (FXS) is associated with disrupted cognition and sleep abnormalities. Sleep loss negatively impacts cognitive function, and one untested possibility is that disrupted cognition in FXS is exacerbated by abnormal sleep. We t
Externí odkaz:
https://doaj.org/article/844290dcb3014c1d90d0fca91935229f
Publikováno v:
World Journal of Otorhinolaryngology-Head and Neck Surgery, Vol 9, Iss 4, Pp 295-301 (2023)
Abstract Background Cutaneous squamous cell carcinoma (CSCC) on the auricle is believed to carry a higher risk of metastatic spread. The rates of lymphatic metastasis reported in the literature have varied widely. There are no established prognostic
Externí odkaz:
https://doaj.org/article/c49f6c4d4ad645aaa388dc2c094126d4
Publikováno v:
Wellcome Open Research, Vol 9 (2024)
The major malaria mosquitoes, Anopheles gambiae s.l and Anopheles funestus, are some of the most studied organisms in medical research and also some of the most genetically diverse. When designing polymerase chain reaction (PCR) or hybridisation-base
Externí odkaz:
https://doaj.org/article/8a44ef50065b4699b52fb19b80d2fc75
Autor:
Arjen E. van’t Hof, Amy Lynd, Ambrose Oruni, Ismail Onyige, Harun Njoroge, Enock Matovu, Martin J. Donnelly
Publikováno v:
Wellcome Open Research, Vol 9 (2024)
Background The effectiveness of long-lasting insecticidal nets (LLINs) are being threatened by growing resistance to pyrethroids. To restore their efficacy, a synergist, piperonyl butoxide (PBO) which inhibits cytochrome P450s has been incorporated i
Externí odkaz:
https://doaj.org/article/52d9dbac34cd475baa3465e5ca181bcc
Autor:
Seline Omondi, Jackline Kosgei, George Musula, Margaret Muchoki, Bernard Abong’o, Silas Agumba, Caroline Ogwang, Daniel P. McDermott, Martin J. Donnelly, Sarah G. Staedke, Jonathan Schultz, Julie R. Gutman, John E. Gimnig, Eric Ochomo
Publikováno v:
Malaria Journal, Vol 22, Iss 1, Pp 1-7 (2023)
Abstract Background Children in Kenya spend a substantial amount of time at school, including at dawn and dusk when mosquitoes are active. With changing vector behaviour towards early morning biting, it is important to determine whether there is an a
Externí odkaz:
https://doaj.org/article/633009f6c37a4c679c8113685d6df30d
Autor:
Rita Sattler, Bryan J. Traynor, Janice Robertson, Ludo Van Den Bosch, Sami J. Barmada, Clive N. Svendsen, Matthew D. Disney, Tania F. Gendron, Philip C. Wong, Martin R. Turner, Adam Boxer, Suma Babu, Michael Benatar, Michael Kurnellas, Jonathan D. Rohrer, Christopher J. Donnelly, Lynette M. Bustos, Kendall Van Keuren-Jensen, Penny A. Dacks, Marwan N. Sabbagh, Attendees of the inaugural C9ORF72 FTD/ALS Summit
Publikováno v:
Neurology and Therapy, Vol 12, Iss 6, Pp 1821-1843 (2023)
Abstract A summit held March 2023 in Scottsdale, Arizona (USA) focused on the intronic hexanucleotide expansion in the C9ORF72 gene and its relevance in frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS; C9ORF72-FTD/ALS). The goal
Externí odkaz:
https://doaj.org/article/29cedee3ed35403a952639263a5b1ede