Výsledky vyhledávání

Type I interferons: expression and signalization

Autor: S. Navarro, G. Uze, J. Doly, A. Civas

Publikováno v: Cellular and Molecular Life Sciences
Cellular and Molecular Life Sciences, Springer Verlag, 1998, 54 (10), pp.1109--1121. ⟨10.1007/s000180050240⟩

Type I interferon (IFN-A and IFN-B) genes encode a large family of multifunctional secreted proteins involved in antiviral defence, cell growth regulation and immune activation. These cytokines, as a consequence of their biological activities, have b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::761143c0dc73b7fa8b2882dcbe60b181
https://pubmed.ncbi.nlm.nih.gov/9817990

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Interleukin-6 and its receptor are expressed by human megakaryocytes: in vitro effects on proliferation and endoreplication

Autor: S, Navarro, N, Debili, J P, Le Couedic, B, Klein, J, Breton-Gorius, J, Doly, W, Vainchenker

Publikováno v: Blood. 77(3)

Interleukin-6 (IL-6) is a pleiotropic cytokine that plays an important role in the megakaryocytic differentiation. Recently, we have observed that IL-6 is synthesized by several human cell lines with megakaryocytic features. In this study, we have in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::bdd32ec922791dcacb77d27f345a9e49
https://pubmed.ncbi.nlm.nih.gov/1991163

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Expression of interleukin 6 and its specific receptor by untreated and PMA-stimulated human erythroid and megakaryocytic cell lines

Autor: S, Navarro, M T, Mitjavila, A, Katz, J, Doly, W, Vainchenker

Publikováno v: Experimental hematology. 19(1)

Different human hematopoietic cell lines were analyzed for the presence of interleukin 6 (IL-6) and IL-6 receptor (IL-6-R). Both IL-6 mRNA and secreted active IL-6 protein were detectable in untreated cell lines with erythroid or megakaryoblastic fea

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e2bfad4f1264e436d0a9f1dc6c0b6df1
https://pubmed.ncbi.nlm.nih.gov/1989890

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Isolation and Characterization of a Functional Murine Interferon Alpha Gene which Is Not Expressed in Fibroblasts upon Virus Induction

Autor: M. Dion, Sébastien Navarro, J. Doly, F. Berlot-Picard, G. Vodjdani

Publikováno v: Journal of General Virology. 70:1381-1389

A mouse genomic segment containing three new members of the murine interferon alpha (MuIFN-alpha) gene family was isolated from a fibroblastic cosmid library. A 4 kb EcoRI fragment contained a new MuIFN-alpha gene named MuIFN-alpha 8. The nucleotide

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4308efddbe423d15c570ae1a62473627
https://doi.org/10.1099/0022-1317-70-6-1381

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Unusually large interferon-α-like mRNAs and high expression of interleukin-6 in human fetal annexes

Autor: C Chany, J Doly, P Duc-Goiran

Publikováno v: Journal of Biological Chemistry. 264:16507-16511

Endogenous interferons (IFNs) with antiviral activity have been detected in human fetal annexes, without any apparent induction. Some are of unusually high molecular weight and antigenic properties (Duc-Goiran P., Robert-Galliot, B., Lopez, J., and C

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8a6bfcc74b20c5d9ecf7c8fc6d8b7b9d
https://doi.org/10.1016/s0021-9258(19)84735-x

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The chloroplast genome of bleached mutants of Euglena gracilis

Autor: J. Doly, G. Bernardi, Victor Nigon, Paul Nicolas, Y. Hussein, Philippe Heizmann

Publikováno v: Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis. 653:412-415

Bleached mutants of Euglena gracilis , traditionally thought to be completely deprived of chloroplast DNA, have been shown to contain a defective chloroplast genome, present at a very low copy number, and preferentially retaining ribosomal RNA genes.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b8a12636e4a7f70826db0a54e834250
https://doi.org/10.1016/0005-2787(81)90197-0

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On the formation of a novel adenylic compound by enzymatic extracts of liver nuclei

Autor: J. Doly, J.D. Weill, Pierre Chambon, Paul Mandel, M.T. Strosser

Publikováno v: Biochemical and Biophysical Research Communications. 25:638-643

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2c42e892d739154c1b6262c8d13a9526
https://doi.org/10.1016/0006-291x(66)90502-x

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ATP-dependent deoxyribonuclease in Bacillus subtilis and a mutant deficient in this activity

Autor: J. Doly, E. Sasarman, C. Anagnostopoulos

Publikováno v: Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 22:15-23

ATP-dependent DNAse activity was measured in rec+ and several rec strains of B. subtilis 168. One of the strains (marker recE5) was found to lack this activity. The enzyme from the wild type was partially purified and some of its properties were dete

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff11934262b53f3cff9fe91faa41c8b9
https://doi.org/10.1016/0027-5107(74)90003-7

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