Zobrazeno 1 - 10
of 21
pro vyhledávání: '"J, Deeths"'
Publikováno v:
Dermatologic Surgery. 42:269-271
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e68b5e155dbe524571852c4e0741cc3a
https://doi.org/10.1097/dss.0000000000000608
https://doi.org/10.1097/dss.0000000000000608
Autor:
Michelle L. Irvin, Marna E. Ericson, Maria K. Hordinsky, Lynne P. Steiner, Matthew J. Deeths, Bart T. Endrizzi
Publikováno v:
Journal of Investigative Dermatology. 126:366-373
This study demonstrates the feasibility and efficacy of using flow cytometric analysis with intracellular cytokine staining for characterization of T-cell phenotype and functional status in extensive alopecia areata (EAA) scalp skin. Cell suspensions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a94908c79f9a43c20ea7ef6b4a94a1d
https://doi.org/10.1038/sj.jid.5700054
https://doi.org/10.1038/sj.jid.5700054
Publikováno v:
The Journal of Immunology. 166:6523-6529
LFA-1 binding to ICAM-I provides a costimulatory signal for CD8+ T cell activation that results in increased IL-2 mRNA levels and protein production to support proliferation. CD28 binding to its B7 ligands has the same effect, and the two costimulato
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0289eb1d524906877831c85145252065
https://doi.org/10.4049/jimmunol.166.11.6523
https://doi.org/10.4049/jimmunol.166.11.6523
Publikováno v:
The Journal of Immunology. 163:102-110
CD8+ T cells stimulated in vitro with anti-TCR mAb and B7-1 or ICAM-1 produce IL-2 and clonally expand. Effector function is acquired within 3 days, but proliferation ceases and the cells begin to die by apoptosis. Stimulation in vivo with B7-1-expre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6b04be8a22939d63ee59ddba42f06200
https://doi.org/10.4049/jimmunol.163.1.102
https://doi.org/10.4049/jimmunol.163.1.102
Autor:
Matthew J. Deeths, Matthew F. Mescher
Publikováno v:
European Journal of Immunology. 29:45-53
The function of purified ICAM-1 in costimulating CD4+ and CD8+ T cell responses has been directly compared to that of B7-1 in a model system that minimizes contributions of other receptor-ligand interactions. While B7-1 costimulates both subsets of T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8a1ceaf0801bf138942099334deaf95a
https://doi.org/10.1002/(sici)1521-4141(199901)29:01<45::aid-immu45>3.0.co
https://doi.org/10.1002/(sici)1521-4141(199901)29:01<45::aid-immu45>3.0.co
Publikováno v:
The Journal of Immunology. 157:2243-2246
It has been suggested that induction of phosphatidylinositol (PI) 3 kinase activity upon CD28 costimulation may contribute to CD28-mediated signaling. In this report, T cell stimulation by microspheres bearing coimmobilized anti-TCR mAb and purified
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0bcc5f06c992052596bec689e716dcff
https://doi.org/10.4049/jimmunol.157.6.2243
https://doi.org/10.4049/jimmunol.157.6.2243
Publikováno v:
Journal of the American Academy of Dermatology. 52(2)
Background Systemic interferon is effective in the treatment of mycosis fungoides (MF). Imiquimod is effective in the treatment of some epidermal neoplasms and induces localized interferon production. Objective To evaluate the safety and efficacy of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::012124d1bad539c7b0ac45503898daf4
https://pubmed.ncbi.nlm.nih.gov/15692473
https://pubmed.ncbi.nlm.nih.gov/15692473
Publikováno v:
Archives of dermatology. 140(3)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8dd49b96c33b0eaf23ef0322f79365cc
https://pubmed.ncbi.nlm.nih.gov/15023782
https://pubmed.ncbi.nlm.nih.gov/15023782
Publikováno v:
Archives of Dermatology. 140
A 52-year-old Hispanic man presented with diffuse violaceous, hyperkeratotic papules, as well as vascularappearing, verrucous nodules and plaques on his lower extremities. The lesions had developed over the preceding 25 years, mainly on his legs, but
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eac40ec86465f394ad7f5e38cbe90a74
https://doi.org/10.1001/archderm.140.3.353-c
https://doi.org/10.1001/archderm.140.3.353-c
Publikováno v:
Molecular urology. 4(3)
We performed a randomized trial to compare the efficacy and toxicity of a new dose of flutamide (500 mg QD) with the currently recommended dose (250 mg q8h) in the treatment of advanced prostate cancer. The primary endpoints were percent of patients
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e71906db5d3f882193be9df298045302
https://pubmed.ncbi.nlm.nih.gov/11062382
https://pubmed.ncbi.nlm.nih.gov/11062382