Zobrazeno 1 - 10
of 804
pro vyhledávání: '"J, Davignon"'
Publikováno v:
Journal of Lipid Research, Vol 38, Iss 7, Pp 1421-1432 (1997)
In order to assess the relationship between plasma accumulation of triglyceride-rich lipoproteins (TRL) and lipoprotein levels of apoC-III and apoE, we have measured apoC-III and apoE in lipoproteins separated according to size (by automated gel filt
Externí odkaz:
https://doaj.org/article/5dada14da123463f938342f0de7d4f46
Publikováno v:
Journal of Lipid Research, Vol 38, Iss 1, Pp 35-48 (1997)
We have used two-dimensional gel electrophoresis to separate and characterize human plasma apolipoprotein (apo) E-containing lipoproteins in the high density lipoprotein (HDL) size range. Lipoproteins were separated from whole plasma by electrophores
Externí odkaz:
https://doaj.org/article/42b7970f65304d0fa17e0f8ad6af644e
Publikováno v:
Journal of Lipid Research, Vol 37, Iss 2, Pp 309-319 (1996)
Familial combined hyperlipoproteinemia (FCH) is a common familial lipoprotein disorder characterized by elevated plasma cholesterol and triglyceride levels with segregation in first-degree relatives. Most affected subjects with FCH have elevated plas
Externí odkaz:
https://doaj.org/article/6ad6660204e545158e160fbdbe037222
Publikováno v:
Journal of Lipid Research, Vol 37, Iss 7, Pp 1422-1435 (1996)
It is proposed that, in hyperlipidemia, foam cells develop in cutaneous xanthomas from the uptake by the macrophage scavenger receptor (SR) of low density lipoproteins (LDL) that are modified due to increased residence time in plasma. We have observe
Externí odkaz:
https://doaj.org/article/ed52def0760c428b9a51e915beb7dff3
Publikováno v:
Journal of Lipid Research, Vol 36, Iss 1, Pp 57-66 (1995)
Apolipoprotein (apo) E mediates the removal of chylomicron and VLDL remnants from plasma. In a proband with mild hyperlipidemia and a family history of premature coronary artery disease, we have identified a new mutant of apoE with an isoelectric poi
Externí odkaz:
https://doaj.org/article/ae5791b71d6f417496fb4ca4a98fbecd
Publikováno v:
Journal of Lipid Research, Vol 36, Iss 1, Pp 117-124 (1995)
It has previously been estimated that due to genetic “founder effects,” 97% of lipoprotein lipase (LPL) gene alleles conferring type I hyperlipoproteinemia (HLP) in French Canadians encode one of the following mutant LPL forms: Gly188–>Glu, Pro
Externí odkaz:
https://doaj.org/article/967bffa840884fde9bfe43983c4d06d1
Publikováno v:
Journal of Lipid Research, Vol 33, Iss 4, Pp 447-454 (1992)
The relationship between apoE phenotype and plasma lipid levels was analyzed in the combined data of published studies. Accordingly, 45 population samples from 17 different countries were included in the analysis. The mean plasma values of cholestero
Externí odkaz:
https://doaj.org/article/16395babbc2e45539154d03ec1cf7e70
Autor:
F Mailly, CF Xu, M Xhignesse, S Lussier-Cacan, PJ Talmud, J Davignon, SE Humphries, AC Nestruck
Publikováno v:
Journal of Lipid Research, Vol 32, Iss 4, Pp 613-620 (1991)
We have found a novel apoE5 mutation, using isoelectric focusing (IEF), in two apparently unrelated French-Canadian subjects. Co-dominant inheritance was demonstrated in the family of the first proband, a healthy male subject. The presence of the apo
Externí odkaz:
https://doaj.org/article/042d3f7065ae4f3d9119be50951d5e3a
Autor:
TL Innerarity, RW Mahley, KH Weisgraber, TP Bersot, RM Krauss, GL Vega, SM Grundy, W Friedl, J Davignon, BJ McCarthy
Publikováno v:
Journal of Lipid Research, Vol 31, Iss 8, Pp 1337-1349 (1990)
Familial defective apolipoprotein B-100 is a genetic disorder of apolipoprotein B-100 that causes moderate to severe hypercholesterolemia. A single amino acid mutation in apolipoprotein B diminishes the ability of low density lipoproteins to bind to
Externí odkaz:
https://doaj.org/article/e84507283cdb4cfaabfc4a320d3b82e2
Publikováno v:
Journal of Lipid Research, Vol 31, Iss 1, Pp 149-155 (1990)
A method for analytical isoelectric focusing (IEF) of apolipoprotein E (apoE) in immobilized pH gradients (IPG) and immunodetection of the separated isoforms has been developed for use with either very low density lipoproteins (VLDL) or whole plasma.
Externí odkaz:
https://doaj.org/article/09f56d946c57433fab9665977d3a528c