Ethnomedicinal Plants with Protective Effects against Beta-Amyloid Peptide (Aβ)1-42 Indicate Therapeutic Potential in a New In Vivo Model of Alzheimer’s Disease

Autor: Norah A. Althobaiti, Farid Menaa, Johnathan J. Dalzell, Aishah E. Albalawi, Hammad Ismail, Mousa A. Alghuthaymi, Reem D. Aldawsari, Haroon Iqbal, Claire McAlinney, Brian D. Green

Publikováno v: Antioxidants, Vol 11, Iss 10, p 1865 (2022)

Alzheimer’s disease (AD) is a progressive neurodegenerative disorder with unmet medical need. This investigation consisted of testing a range of ethanolic ethnomedicinal plant extracts (n = 18) traditionally used in the treatment of disorders such

Externí odkaz: https://doaj.org/article/590dbbe256f544d6aaff5905a0d37bac

Can Woodchip Bioreactors Be Used at a Catchment Scale? Nitrate Performance and Sediment Considerations

Autor: Gary W. Feyereisen, Ehsan Ghane, Todd W. Schumacher, Brent J. Dalzell, M. R. Williams

Publikováno v: Journal of the ASABE. 66:367-379

Highlights Novel three-bed, cascading-inlet bioreactor treated agricultural drainage from a 249-ha catchment. Nitrate removal rates and load reduction efficiencies were similar to those of traditional single-field bioreactors. Sedimentation problems

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d03983d5f7b90f03da4e408b0092747f
https://doi.org/10.13031/ja.15496

Mass spectrometry-driven discovery of neuropeptides mediating nictation behavior of nematodes

Autor: Bram Cockx, Sven Van Bael, Rose Boelen, Elke Vandewyer, Heeseung Yang, Tuan Anh Le, Johnathan J. Dalzell, Isabel Beets, Christina Ludwig, Junho Lee, Liesbet Temmerman

Publikováno v: Cockx, B, Van Bael, S, Boelen, R, Vandewyer, E, Yang, H, Le, T A, Dalzell, J J, Beets, I, Ludwig, C, Lee, J & Temmerman, L 2023, ' Mass spectrometry-driven discovery of neuropeptides mediating nictation behavior of nematodes ', Molecular and Cellular Proteomics, vol. 22, no. 2, 100479 . https://doi.org/10.1016/j.mcpro.2022.100479

Neuropeptides regulate animal physiology and behavior, making them widely studied targets of functional genetics research. While the field often relies on differential -omics approaches to build hypotheses, no such method exists for neuropeptidomics.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2e437208fa89f340acb0934c329e017
https://pure.qub.ac.uk/en/publications/2d030ad5-7804-4b12-b843-d3a10986d67b

A neuropeptide modulates sensory perception in the entomopathogenic nematode Steinernema carpocapsae.

Autor: Robert Morris, Leonie Wilson, Matthew Sturrock, Neil D Warnock, Daniel Carrizo, Deborah Cox, Aaron G Maule, Johnathan J Dalzell

Publikováno v: PLoS Pathogens, Vol 13, Iss 3, p e1006185 (2017)

Entomopathogenic nematodes (EPNs) employ a sophisticated chemosensory apparatus to detect potential hosts. Understanding the molecular basis of relevant host-finding behaviours could facilitate improved EPN biocontrol approaches, and could lend insig

Externí odkaz: https://doaj.org/article/6107377126274354955633951aaea459

Local stability properties of complex, species-rich soil food webs with functional block structure

Autor: Matthias C. Rillig, Thomas Bolger, Diana H. Wall, Maarja Öpik, Tancredi Caruso, Jacopo Grilli, Francisco de Castro, Aaron G. Maule, Sina M. Adl, Zoë Lindo, Richard D. Bardgett, Thomas Fleming, Johnathan J. Dalzell, Franciska T. de Vries, Silja Emilia Hannula, Diego Garlaschelli, Stavros D. Veresoglou, Stefano Allesina, Mark C. Emmerson

Publikováno v: Ecology and Evolution, 11(22), 16070-16081. WILEY
Ecology and Evolution, 11(22), 16070-16081. John Wiley and Sons Ltd
de Castro, F, Adl, S M, Allesina, S, Bardgett, R D, Bolger, T, Dalzell, J J, Emmerson, M, Fleming, T, Garlaschelli, D, Grilli, J, Hannula, S E, de Vries, F, Lindo, Z, Maule, A G, Öpik, M, Rillig, M C, Veresoglou, S D, Wall, D H & Caruso, T 2021, ' Local stability properties of complex, species-rich soil food webs with functional block structure ', Ecology and Evolution, vol. 11, no. 22, pp. 16070-16081 . https://doi.org/10.1002/ece3.8278, https://doi.org/10.1002/ece3.8278
Ecology and Evolution
Ecology and Evolution, Vol 11, Iss 22, Pp 16070-16081 (2021)

Ecologists have long debated the properties that confer stability to complex, species‐rich ecological networks. Species‐level soil food webs are large and structured networks of central importance to ecosystem functioning. Here, we conducted an a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b763b3b919543884f98c8373b5aeb9bf
https://hdl.handle.net/20.500.11755/ca9f6fd7-1d20-45cc-9c50-38205f1f62d3