Zobrazeno 1 - 10
of 139
pro vyhledávání: '"J, Colicelli"'
Publikováno v:
Research. 2
Autor:
Michael Wigler, Michael Riggs, C. Birchmeier, Linda Rodgers, John J. Colicelli, Charles Nicolette
Publikováno v:
Scopus-Elsevier
Saccharomyces cerevisiae strains expressing the activated RAS2Val19 gene or lacking both cAMP phosphodiesterase genes, PDE1 and PDE2, have impaired growth control and display an acute sensitivity to heat shock. We have isolated two classes of mammali
Publikováno v:
Scopus-Elsevier
Large deletion and small insertion mutations in the adenylyl cyclase gene of Saccharomyces cerevisiae were used to map regions required for activation by RAS protein in vitro. The amino-terminal 605 amino acids were found to be dispensable for respon
Autor:
Michael Riggs, K. Ferguson, Jeffrey E. Gerst, Jeffrey Field, R. Ballester, Scott Powers, Graeme Bolger, Anne Vojtek, T. Michaeli, Tohru Kataoka, B. Wheland, Michael Wigler, Linda Rodgers, Ilse Wieland, John J. Colicelli
Publikováno v:
Scopus-Elsevier
Adenylyl cyclase from S. cerevisiae contains at least two subunits, a 200 kd catalytic subunit and a subunit with an apparent molecular size of 70 kd, which we now call CAP (cyclase-associated protein). We cloned a cDNA encoding CAP by screening a ye
Autor:
T. Michaeli, Philip M. Sass, John J. Colicelli, R. Ballester, Hao-Peng Xu, Jeffrey Field, Michael Wigler
Publikováno v:
Scopus-Elsevier
The interaction between RAS proteins and adenylyl cyclase was studied by using dominant interfering mutations of adenylyl cyclase from the yeast Saccharomyces cerevisiae. RAS proteins activate adenylyl cyclase in this organism. A plasmid expressing a
Autor:
John J. Colicelli
Epigenetic gene silencing is a common element of breast cancers. The specific genes targeted and the mechanisms of silencing, and how these relate to disease progression and outcome, are not well understood. This research project has 1) identified a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::97461f3a4ceb08a618efb6b0c7628c54
https://doi.org/10.21236/ada437102
https://doi.org/10.21236/ada437102
Autor:
Y, Wang, J, Colicelli
Publikováno v:
Methods in enzymology. 332
Autor:
M I, Shuster, L, Han, M M, Le Beau, E, Davis, M, Sawicki, C M, Lese, N H, Park, J, Colicelli, S M, Gollin
Publikováno v:
Genes, chromosomescancer. 28(2)
Gene amplification is a common feature of tumors. Overexpression of some amplified genes plays a role in tumor progression. Gene amplification can occur either extrachromosomally as double-minute chromosomes (dmin) or intrachromosomally in the form o
Publikováno v:
Journal of Virology. 49:918-924
We have constructed a series of deletion mutations in the p30 and p10 domains of the gag gene of Moloney murine leukemia virus. Mutants with deletions in P30 were completely defective in virion particle production even though an altered gag precursor
Publikováno v:
Journal of Virology. 46:538-546
A series of deletion mutations localized near the 5' end of the Moloney murine leukemia virus genome was generated by site-specific mutagenesis of cloned viral DNA. The mutants recovered from such deleted DNAs failed to synthesize the normal glycosyl